Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2052 | 2013 |
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin T Schneider-Poetsch, J Ju, DE Eyler, Y Dang, S Bhat, WC Merrick, ... Nature chemical biology 6 (3), 209-217, 2010 | 1109 | 2010 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 864 | 2015 |
Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms B Shen Current opinion in chemical biology 7 (2), 285-295, 2003 | 857 | 2003 |
A new golden age of natural products drug discovery B Shen Cell 163 (6), 1297-1300, 2015 | 715 | 2015 |
Decoding human cytomegalovirus N Stern-Ginossar, B Weisburd, A Michalski, VTK Le, MY Hein, SX Huang, ... Science 338 (6110), 1088-1093, 2012 | 712 | 2012 |
Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution S Lee, B Liu, S Lee, SX Huang, B Shen, SB Qian Proceedings of the National Academy of Sciences 109 (37), E2424-E2432, 2012 | 663 | 2012 |
Antitumor antibiotics: bleomycin, enediynes, and mitomycin U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen Chemical Reviews 105 (2), 739-758, 2005 | 648 | 2005 |
Synthetic biology to access and expand nature's chemical diversity MJ Smanski, H Zhou, J Claesen, B Shen, MA Fischbach, CA Voigt Nature Reviews Microbiology 14 (3), 135-149, 2016 | 532 | 2016 |
A genomics-guided approach for discovering and expressing cryptic metabolic pathways E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ... Nature biotechnology 21 (2), 187-190, 2003 | 408 | 2003 |
The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide … L Du, C Sánchez, M Chen, DJ Edwards, B Shen Chemistry & biology 7 (8), 623-642, 2000 | 383 | 2000 |
Biosynthesis of the enediyne antitumor antibiotic C-1027 W Liu, SD Christenson, S Standage, B Shen Science 297 (5584), 1170-1173, 2002 | 352 | 2002 |
Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis YQ Cheng, GL Tang, B Shen Proceedings of the National Academy of Sciences 100 (6), 3149-3154, 2003 | 349 | 2003 |
Hybrid peptide–polyketide natural products: biosynthesis and prospects toward engineering novel molecules L Du, C Sánchez, B Shen Metabolic engineering 3 (1), 78-95, 2001 | 298 | 2001 |
Intrinsic fluorescence from DNA can be enhanced by metallic particles JR Lakowicz, B Shen, Z Gryczynski, S D'Auria, I Gryczynski Biochemical and Biophysical Research Communications 286 (5), 875-879, 2001 | 280 | 2001 |
Quantitative profiling of initiating ribosomes in vivo X Gao, J Wan, B Liu, M Ma, B Shen, SB Qian Nature methods 12 (2), 147-153, 2015 | 238 | 2015 |
Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications R Liao, L Duan, C Lei, H Pan, Y Ding, Q Zhang, D Chen, B Shen, Y Yu, ... Chemistry & biology 16 (2), 141-147, 2009 | 232 | 2009 |
Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide–polyketide antitumor drug bleomycin C Sánchez, L Du, DJ Edwards, MD Toney, B Shen Chemistry & biology 8 (7), 725-738, 2001 | 218 | 2001 |
Microbial genomics for the improvement of natural product discovery SG Van Lanen, B Shen Current opinion in microbiology 9 (3), 252-260, 2006 | 217 | 2006 |
Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase GL Tang, YQ Cheng, B Shen Chemistry & biology 11 (1), 33-45, 2004 | 206 | 2004 |