Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes I Guijarro-Muñoz, M Compte, A Álvarez-Cienfuegos, L Álvarez-Vallina, ... Journal of Biological Chemistry 289 (4), 2457-2468, 2014 | 325 | 2014 |
Immune regulation by pericytes: modulating innate and adaptive immunity R Navarro, M Compte, L Álvarez-Vallina, L Sanz Frontiers in immunology 7, 480, 2016 | 159 | 2016 |
The coming of age of engineered multivalent antibodies N Nunez-Prado, M Compte, S Harwood, A Alvarez-Mendez, S Lykkemark, ... Drug discovery today 20 (5), 588-594, 2015 | 155 | 2015 |
Antibodies and gene therapy: teaching old ‘magic bullets’ new tricks L Sanz, B Blanco, L Alvarez-Vallina TRENDS in Immunology 25 (2), 85-91, 2004 | 128 | 2004 |
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity M Compte, SL Harwood, IG Muñoz, R Navarro, M Zonca, G Perez-Chacon, ... Nature communications 9 (1), 4809, 2018 | 127 | 2018 |
Engagement of α4β1 integrin by fibronectin induces in vitro resistance of B chronic lymphocytic leukemia cells to fludarabine MT de la Fuente, B Casanova, JV Moyano, M Garcia-Gila, L Sanz, ... Journal of leukocyte biology 71 (3), 495-502, 2002 | 125 | 2002 |
EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination L Gómez-Maldonado, M Tiana, O Roche, A Prado-Cabrero, L Jensen, ... Oncogene 34 (20), 2609-2620, 2015 | 117 | 2015 |
Tumor immunotherapy using gene-modified human mesenchymal stem cells loaded into synthetic extracellular matrix scaffolds M Compte, ÁM Cuesta, D Sánchez-Martín, V Alonso-Camino, JL Vicario, ... Stem cells 27 (3), 753-760, 2009 | 116 | 2009 |
Long-term in vivo imaging of human angiogenesis: critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels L Sanz, P Santos-Valle, V Alonso-Camino, C Salas, A Serrano, JL Vicario, ... Microvascular research 75 (3), 308-314, 2008 | 99 | 2008 |
Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA× anti-CD3 diabodies from lentivirally transduced human lymphocytes M Compte, B Blanco, F Serrano, ÁM Cuesta, L Sanz, A Bernad, P Holliger, ... Cancer gene therapy 14 (4), 380-388, 2007 | 80 | 2007 |
Antibody engineering: facing new challenges in cancer therapy1 L Sanz, ÁM Cuesta, M Compte, L ÁLVAREZ‐VALLINA Acta Pharmacologica Sinica 26 (6), 641-648, 2005 | 79 | 2005 |
In Vivo Tumor Targeting and Imaging with Engineered Trivalent Antibody Fragments Containing Collagen-Derived Sequences AM Cuesta, D Sánchez-Martín, L Sanz, J Bonet, M Compte, L Kremer, ... PLoS One 4 (4), e5381, 2009 | 77 | 2009 |
ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy SL Harwood, A Alvarez-Cienfuegos, N Nuñez-Prado, M Compte, ... Oncoimmunology 7 (1), e1377874, 2018 | 76 | 2018 |
Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell … L Sanz, P Kristensen, B Blanco, S Facteau, SJ Russell, G Winter, ... Gene Therapy 9 (15), 1049-1053, 2002 | 64 | 2002 |
Bcl-2 family gene modulation during spontaneous apoptosis of B-chronic lymphocytic leukemia cells L Sanz, JA Garcia-Marco, B Casanova, MT de la Fuente, M Garcı́a-Gila, ... Biochemical and biophysical research communications 315 (3), 562-567, 2004 | 59 | 2004 |
Enhanced antiangiogenic therapy with antibody‐collagen XVIII NC1 domain fusion proteins engineered to exploit matrix remodeling events VJ Sánchez‐Arévalo Lobo, ÁM Cuesta, L Sanz, M Compte, P García, ... International journal of cancer 119 (2), 455-462, 2006 | 49 | 2006 |
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis I Guijarro-Munoz, AM Cuesta, A Alvarez-Cienfuegos, JG Geng, ... Experimental Cell Research 318 (4), 371-378, 2012 | 47 | 2012 |
HLA class I and class II allele distribution in the Bubi population from the island of Bioko (Equatorial Guinea) R De Pablo, JM Garcia‐Pacheco, C Vilches, ME Moreno, L Sanz, ... Tissue Antigens 50 (6), 593-601, 1997 | 47 | 1997 |
Delivery of CCL21 to metastatic disease improves the efficacy of adoptive T-cell therapy U Thanarajasingam, L Sanz, R Diaz, J Qiao, L Sanchez-Perez, T Kottke, ... Cancer research 67 (1), 300-308, 2007 | 44 | 2007 |
Selection strategies for anticancer antibody discovery: searching off the beaten path D Sánchez-Martín, MD Sørensen, S Lykkemark, L Sanz, P Kristensen, ... Trends in biotechnology 33 (5), 292-301, 2015 | 42 | 2015 |