Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner M Frank, S Duvezin-Caubet, S Koob, A Occhipinti, R Jagasia, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (12), 2297-2310, 2012 | 519 | 2012 |
Mitochondria bound to lipid droplets have unique bioenergetics, composition, and dynamics that support lipid droplet expansion IY Benador, M Veliova, K Mahdaviani, A Petcherski, JD Wikstrom, ... Cell metabolism 27 (4), 869-885. e6, 2018 | 465 | 2018 |
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway X Lojewski, JF Staropoli, S Biswas-Legrand, AM Simas, L Haliw, MK Selig, ... Human molecular genetics 23 (8), 2005-2022, 2014 | 148 | 2014 |
A novel approach to measure mitochondrial respiration in frozen biological samples R Acin‐Perez, IY Benador, A Petcherski, M Veliova, GA Benavides, ... The EMBO journal 39 (13), e104073, 2020 | 147 | 2020 |
Unbiased cell-based screening in a neuronal cell model of Batten disease highlights an interaction between Ca2+ homeostasis, autophagy, and CLN3 protein function U Chandrachud, MW Walker, AM Simas, S Heetveld, A Petcherski, ... Journal of Biological Chemistry 290 (23), 14361-14380, 2015 | 93 | 2015 |
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease KD Alysandratos, SJ Russo, A Petcherski, EP Taddeo, R Acín-Pérez, ... Cell reports 36 (9), 2021 | 74 | 2021 |
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity R Acín-Pérez, S Iborra, Y Martí-Mateos, ECL Cook, R Conde-Garrosa, ... Nature metabolism 2 (9), 974-988, 2020 | 53 | 2020 |
The biology of lipid droplet-bound mitochondria M Veliova, A Petcherski, M Liesa, OS Shirihai Seminars in cell & developmental biology 108, 55-64, 2020 | 49 | 2020 |
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer M Han, EA Bushong, M Segawa, A Tiard, A Wong, MR Brady, ... Nature 615 (7953), 712-719, 2023 | 47 | 2023 |
Cell cycle–related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line C Montemurro, S Vadrevu, T Gurlo, AE Butler, KE Vongbunyong, ... Cell Cycle 16 (21), 2086-2099, 2017 | 42 | 2017 |
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling M Veliova, CM Ferreira, IY Benador, AE Jones, K Mahdaviani, ... EMBO reports 21 (12), e49634, 2020 | 41 | 2020 |
Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation A Weigert, A von Knethen, D Thomas, I Faria, D Namgaladze, E Zezina, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 36 | 2019 |
Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet‐Induced Insulin Resistance in Mice J Yang, Y Guo, SM Henning, B Chan, J Long, J Zhong, R Acin‐Perez, ... Molecular nutrition & food research 64 (19), 2000091, 2020 | 35 | 2020 |
FRET-assisted determination of CLN3 membrane topology E Ratajczak, A Petcherski, J Ramos-Moreno, MO Ruonala PLoS One 9 (7), e102593, 2014 | 33 | 2014 |
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease J Zeng, R Acin-Perez, EA Assali, A Martin, AJ Brownstein, A Petcherski, ... Nature communications 14 (1), 2573, 2023 | 31 | 2023 |
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue R Acín-Perez, A Petcherski, M Veliova, IY Benador, EA Assali, ... Redox Biology 46, 102087, 2021 | 19 | 2021 |
Altered expression of ganglioside metabolizing enzymes results in GM3 ganglioside accumulation in cerebellar cells of a mouse model of juvenile neuronal ceroid lipofuscinosis A Somogyi, A Petcherski, B Beckert, M Huebecker, DA Priestman, ... International journal of molecular sciences 19 (2), 625, 2018 | 18 | 2018 |
Elamipretide promotes mitophagosome formation and prevents its reduction induced by nutrient excess in INS1 β-cells A Petcherski, KM Trudeau, DM Wolf, M Segawa, J Lee, EP Taddeo, ... Journal of molecular biology 430 (24), 4823-4833, 2018 | 15 | 2018 |
An autophagy modifier screen identifies small molecules capable of reducing autophagosome accumulation in a model of CLN3-mediated neurodegeneration A Petcherski, U Chandrachud, ES Butz, MC Klein, WN Zhao, SA Reis, ... Cells 8 (12), 1531, 2019 | 14 | 2019 |
MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy FM Cerqueira, N Kozer, A Petcherski, BM Baranovski, D Wolf, EA Assali, ... Biochemical Journal 477 (2), 461-475, 2020 | 11 | 2020 |