ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair M Tsuda, K Cho, M Ooka, N Shimizu, R Watanabe, A Yasui, Y Nakazawa, ... PLoS One 12 (11), e0188320, 2017 | 44 | 2017 |
Two-dimensional cellular and three-dimensional bio-printed skin models to screen topical-use compounds for irritation potential Z Wei, X Liu, M Ooka, L Zhang, MJ Song, R Huang, NC Kleinstreuer, ... Frontiers in bioengineering and biotechnology 8, 109, 2020 | 42 | 2020 |
Application of in vitro metabolism activation in high-throughput screening M Ooka, C Lynch, M Xia International journal of molecular sciences 21 (21), 8182, 2020 | 41 | 2020 |
Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites T Abe, M Ooka, R Kawasumi, K Miyata, M Takata, K Hirota, D Branzei Proceedings of the National Academy of Sciences 115 (33), 8412-8417, 2018 | 41 | 2018 |
The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C) M Tsuda, K Terada, M Ooka, K Kobayashi, H Sasanuma, R Fujisawa, ... Oncotarget 8 (20), 33457, 2017 | 38 | 2017 |
The SARS-CoV-2 spike protein binds and modulates estrogen receptors O Solis, AR Beccari, D Iaconis, C Talarico, CA Ruiz-Bedoya, ... Science Advances 8 (48), eadd4150, 2022 | 25 | 2022 |
Profiling the Tox21 chemical collection for acetylcholinesterase inhibition S Li, J Zhao, R Huang, J Travers, C Klumpp-Thomas, W Yu, ... Environmental Health Perspectives 129 (4), 047008, 2021 | 23 | 2021 |
Liver three-dimensional cellular models for high-throughput chemical testing S Yang, M Ooka, RJ Margolis, M Xia Cell Reports Methods 3 (3), 2023 | 22 | 2023 |
PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching M Tsuda, S Ogawa, M Ooka, K Kobayashi, K Hirota, M Wakasugi, ... PLoS One 14 (3), e0213383, 2019 | 21 | 2019 |
Cytotoxic and genotoxic profiles of benzo [a] pyrene and N-nitrosodimethylamine demonstrated using DNA repair deficient DT40 cells with metabolic activation M Ooka, H Takazawa, S Takeda, K Hirota Chemosphere 144, 1901-1907, 2016 | 21 | 2016 |
Development of a targeted flip-in system in avian DT40 cells K Kobayashi, T Fujii, R Asada, M Ooka, K Hirota PLoS One 10 (3), e0122006, 2015 | 20 | 2015 |
XRCC1 counteracts poly (ADP ribose) polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped … K Hirota, M Ooka, N Shimizu, K Yamada, M Tsuda, MA Ibrahim, ... Genes to Cells 27 (5), 331-344, 2022 | 18 | 2022 |
Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression M Ooka, T Abe, K Cho, K Koike, S Takeda, K Hirota PLoS One 13 (2), e0192421, 2018 | 18 | 2018 |
SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells A Nakazato, K Kajita, M Ooka, R Akagawa, T Abe, S Takeda, D Branzei, ... DNA repair 68, 50-57, 2018 | 16 | 2018 |
Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation M Ooka, J Zhao, P Shah, J Travers, C Klumpp-Thomas, X Xu, R Huang, ... Archives of toxicology 96 (7), 1975-1987, 2022 | 15 | 2022 |
Determination of genotoxic potential by comparison of structurally related azo dyes using DNA repair-deficient DT40 mutant panels M Ooka, K Kobayashi, T Abe, K Akiyama, M Hada, S Takeda, K Hirota Chemosphere 164, 106-112, 2016 | 14 | 2016 |
Distinct DNA damage spectra induced by ionizing radiation in normoxic and hypoxic cells N Shimizu, M Ooka, T Takagi, S Takeda, K Hirota Radiation research 184 (4), 442-448, 2015 | 11 | 2015 |
Pold4, the fourth subunit of replicative polymerase δ, suppresses gene conversion in the immunoglobulin-variable gene in avian DT40 cells K Kojima, M Ooka, T Abe, K Hirota DNA repair 100, 103056, 2021 | 4 | 2021 |
High-throughput screening to advance in vitro toxicology: Accomplishments, challenges, and future directions C Lynch, S Sakamuru, M Ooka, R Huang, C Klumpp-Thomas, P Shinn, ... Annual review of pharmacology and toxicology 64 (1), 191-209, 2024 | 3 | 2024 |
Lestaurtinib induces DNA damage that is related to estrogen receptor activation M Ooka, S Yang, L Zhang, K Kojima, R Huang, K Hirota, S Takeda, M Xia Current Research in Toxicology 4, 100102, 2023 | 1 | 2023 |