关注
C. Frank Bennett
C. Frank Bennett
Ionis Pharmaceuticals
在 ionisph.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
C Esau, S Davis, SF Murray, XX Yu, SK Pandey, M Pear, L Watts, ...
Cell metabolism 3 (2), 87-98, 2006
26062006
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
V Tripathi, JD Ellis, Z Shen, DY Song, Q Pan, AT Watt, SM Freier, ...
Molecular cell 39 (6), 925-938, 2010
24342010
Nusinersen versus sham control in infantile-onset spinal muscular atrophy
RS Finkel, E Mercuri, BT Darras, AM Connolly, NL Kuntz, J Kirschner, ...
New England Journal of Medicine 377 (18), 1723-1732, 2017
20552017
RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform
CF Bennett, EE Swayze
Annual review of pharmacology and toxicology 50 (1), 259-293, 2010
15292010
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ...
Nature neuroscience 14 (4), 459-468, 2011
13912011
MicroRNA-143 regulates adipocyte differentiation
C Esau, X Kang, E Peralta, E Hanson, EG Marcusson, LV Ravichandran, ...
Journal of Biological Chemistry 279 (50), 52361-52365, 2004
13392004
Nusinersen versus sham control in later-onset spinal muscular atrophy
E Mercuri, BT Darras, CA Chiriboga, JW Day, C Campbell, AM Connolly, ...
New England Journal of Medicine 378 (7), 625-635, 2018
12792018
Antisense oligonucleotide modulation of multidrug resistance-associated protein
E Baracchini, CF Bennett, NM Dean
US Patent 5,801,154, 1998
11271998
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
RS Finkel, CA Chiriboga, J Vajsar, JW Day, J Montes, DC De Vivo, ...
The Lancet 388 (10063), 3017-3026, 2016
10392016
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ...
Neuron 80 (2), 415-428, 2013
10312013
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.
CF Bennett, MY Chiang, H Chan, JE Shoemaker, CK Mirabelli
Molecular pharmacology 41 (6), 1023-1033, 1992
8791992
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
F Li, EJ Ackermann, CF Bennett, AL Rothermel, J Plescia, S Tognin, ...
Nature cell biology 1 (8), 461-466, 1999
8681999
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis
HB Kordasiewicz, LM Stanek, EV Wancewicz, C Mazur, MM McAlonis, ...
Neuron 74 (6), 1031-1044, 2012
8582012
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ...
Nature neuroscience 15 (11), 1488-1497, 2012
8312012
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents: a comparative analysis
TA Vickers, S Koo, CF Bennett, ST Crooke, NM Dean, BF Baker
Journal of Biological Chemistry 278 (9), 7108-7118, 2003
7872003
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
Y Hua, K Sahashi, F Rigo, G Hung, G Horev, CF Bennett, AR Krainer
Nature 478 (7367), 123-126, 2011
7772011
Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion
D Sareen, JG O’Rourke, P Meera, A Muhammad, S Grant, M Simpkinson, ...
Science translational medicine 5 (208), 208ra149-208ra149, 2013
7752013
Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides
RS Geary, D Norris, R Yu, CF Bennett
Advanced drug delivery reviews 87, 46-51, 2015
7732015
Regulating gene expression through RNA nuclear retention
KV Prasanth, SG Prasanth, Z Xuan, S Hearn, SM Freier, CF Bennett, ...
Cell 123 (2), 249-263, 2005
7592005
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
Y Hua, K Sahashi, G Hung, F Rigo, MA Passini, CF Bennett, AR Krainer
Genes & development 24 (15), 1634-1644, 2010
7492010
系统目前无法执行此操作,请稍后再试。
文章 1–20