Oxidative protection of hemoglobin and hemerythrin by cross-linking with a nonheme iron peroxidase: potentially improved oxygen carriers for use in blood substitutes D Hathazi, AC Mot, A Vaida, F Scurtu, I Lupan, E Fischer-Fodor, ... Biomacromolecules 15 (5), 1920-1927, 2014 | 40 | 2014 |
Towards hemerythrin-based blood substitutes: Comparative performance to hemoglobin on human leukocytes and umbilical vein endothelial cells E Fischer-Fodor, A Mot, F Deac, M Arkosi, R Silaghi-Dumitrescu Journal of Biosciences 36, 215-221, 2011 | 29 | 2011 |
The reaction of oxy hemoglobin with nitrite: Mechanism, antioxidant-modulated effect, and implications for blood substitute evaluation D Hathazi, F Scurtu, C Bischin, A Mot, AAA Attia, J Kongsted, ... Molecules 23 (2), 350, 2018 | 28 | 2018 |
Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry R Silaghi-Dumitrescu, DA Svistunenko, D Cioloboc, C Bischin, F Scurtu, ... Nitric Oxide 42, 32-39, 2014 | 27 | 2014 |
Comparative In Vivo Effects of Hemoglobin-Based Oxygen Carriers (HBOC) with Varying Prooxidant and Physiological Reactivity VA Toma, AD Farcaș, I Roman, B Sevastre, D Hathazi, F Scurtu, ... PLoS One 11 (4), e0153909, 2016 | 25 | 2016 |
Hemoglobin–albumin cross-linking with disuccinimidyl suberate (DSS) and/or glutaraldehyde for blood substitutes F Scurtu, O Zolog, B Iacob, R Silaghi-Dumitrescu Artificial Cells, Nanomedicine, and Biotechnology 42 (1), 13-17, 2014 | 22 | 2014 |
Derivatization of haemoglobin with periodate-generated reticulation agents: evaluation of oxidative reactivity for potential blood substitutes F Deac, B Iacob, E Fischer-Fodor, G Damian, R Silaghi-Dumitrescu The journal of biochemistry 149 (1), 75-82, 2011 | 20 | 2011 |
Ascorbate peroxidase activity of cytochrome c C Bischin, F Deac, R Silaghi-Dumitrescu, JAR Worrall, BS Rajagopal, ... Free Radical Research 45 (4), 439-444, 2011 | 19 | 2011 |
Stability of glutaraldehyde in biocide compositions A Matei, C Puscas, I Patrascu, M Lehene, J Ziebro, F Scurtu, M Baia, ... International journal of molecular sciences 21 (9), 3372, 2020 | 18 | 2020 |
The high affinity of small-molecule antioxidants for hemoglobin C Puscas, L Radu, F Carrascoza, AC Mot, D Amariei, O Lungu, F Scurtu, ... Free Radical Biology and Medicine 124, 260-274, 2018 | 18 | 2018 |
Protein-based blood substitutes: recent attempts at controlling pro-oxidant reactivity with and beyond hemoglobin VF Scurtu, AC Moţ, R Silaghi-Dumitrescu Pharmaceuticals 6 (7), 867-880, 2013 | 17 | 2013 |
Hemoglobin-albumin crosslinked copolymers: reduced prooxidant reactivity B Iacob, F Deac, D Cioloboc, G Damian, R Silaghi-Dumitrescu Artificial Cells, Blood Substitutes, and Biotechnology 39 (5), 293-297, 2011 | 17 | 2011 |
A new polyethyleneglycol-derivatized hemoglobin derivative with decreased oxygen affinity and limited toxicity O Zolog, A Mot, F Deac, A Roman, E Fischer-Fodor, R Silaghi-Dumitrescu The Protein Journal 30, 27-31, 2011 | 17 | 2011 |
Ascorbate binding to globins FV Deac, A Todea, AM Bolfa, P Podea, P Petrar, R Silaghi-Dumitrescu Rom. J. Biochem 46, 115-121, 2009 | 14 | 2009 |
In vivo evaluation of hemerythrin-based oxygen carriers: Similarities with hemoglobin-based counterparts VA Toma, AD Farcas, I Roman, B Sevastre, D Hathazi, F Scurtu, ... International journal of biological macromolecules 107, 1422-1427, 2018 | 13 | 2018 |
Copolymerization of recombinant Phascolopsis gouldii hemerythrin with human serum albumin for use in blood substitutes M Arkosi, F Scurtu, A Vulpoi, R Silaghi-Dumitrescu, D Kurtz Jr Artificial Cells, Nanomedicine, and Biotechnology 45 (2), 218-223, 2017 | 12 | 2017 |
Involvement of ferryl in the reaction between nitrite and the oxy forms of globins D Hathazi, SD Mahuţ, FV Scurtu, C Bischin, C Stanciu, AA Attia, G Damian, ... JBIC Journal of Biological Inorganic Chemistry 19, 1233-1239, 2014 | 11 | 2014 |
Excess ascorbate is a chemical stress agent against proteins and cells M Lehene, E Fischer-Fodor, F Scurtu, ND Hădade, E Gal, AC Mot, A Matei, ... Pharmaceuticals 13 (6), 107, 2020 | 10 | 2020 |
Hemoglobin-based blood substitutes: which hemoglobin to use? FV Deac, AM Bolfa, C Magdas, B Sevastre, S Turc, R Silaghi-Dumitrescu | 9 | 2010 |
Effects of polystyrene nanoplastics exposure on in vitro-grown Stevia rebaudiana plants V Coman, VF Scurtu, C Coman, D Clapa, ȘD Iancu, N Leopold, ... Plant Physiology and Biochemistry 197, 107634, 2023 | 8 | 2023 |