G-quadruplex formation at the 3′ end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase Q Wang, J Liu, Z Chen, K Zheng, C Chen, Y Hao, Z Tan Nucleic acids research 39 (14), 6229-6237, 2011 | 191 | 2011 |
Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA K Zheng, Z Chen, Y Hao, Z Tan Nucleic acids research 38 (1), 327-338, 2010 | 158 | 2010 |
Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control K Zheng, S Xiao, J Liu, J Zhang, Y Hao, Z Tan Nucleic acids research 41 (10), 5533-5541, 2013 | 146 | 2013 |
Detection of genomic G-quadruplexes in living cells using a small artificial protein K Zheng, J Zhang, Y He, J Gong, C Wen, J Chen, Y Hao, Y Zhao, Z Tan Nucleic acids research 48 (20), 11706-11720, 2020 | 127 | 2020 |
Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives X Li, K Zheng, J Zhang, H Liu, Y He, B Yuan, Y Hao, Z Tan Proceedings of the National Academy of Sciences 112 (47), 14581-14586, 2015 | 105 | 2015 |
Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition Z Chen, K Zheng, Y Hao, Z Tan Journal of the American Chemical Society 131 (30), 10430-10438, 2009 | 84 | 2009 |
Mechanism and manipulation of DNA: RNA hybrid G-quadruplex formation in transcription of G-rich DNA J Zhang, K Zheng, S Xiao, Y Hao, Z Tan Journal of the American Chemical Society 136 (4), 1381-1390, 2014 | 79 | 2014 |
DNA G-quadruplex formation in response to remote downstream transcription activity: long-range sensing and signal transducing in DNA double helix C Zhang, H Liu, K Zheng, Y Hao, Z Tan Nucleic acids research 41 (14), 7144-7152, 2013 | 77 | 2013 |
A competitive formation of DNA: RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site K Zheng, R Wu, Y He, S Xiao, J Zhang, J Liu, Y Hao, Z Tan Nucleic acids research 42 (16), 10832-10844, 2014 | 71 | 2014 |
Bioinformatic analysis reveals an evolutional selection for DNA: RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals S Xiao, J Zhang, K Zheng, Y Hao, Z Tan Nucleic acids research 41 (22), 10379-10390, 2013 | 70 | 2013 |
Formation of DNA: RNA Hybrid G‐Quadruplex in Bacterial Cells and Its Dominance over the Intramolecular DNA G‐Quadruplex in Mediating Transcription Termination R Wu, K Zheng, J Zhang, Y Hao, Z Tan Angewandte Chemie International Edition 54 (8), 2447-2451, 2015 | 56 | 2015 |
Kinetic and thermodynamic control of G‐quadruplex folding Y Xue, J Liu, K Zheng, Z Kan, Y Hao, Z Tan Angewandte Chemie International Edition 50 (35), 8046-8050, 2011 | 48 | 2011 |
G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity J Gong, C Wen, M Tang, R Duan, J Chen, J Zhang, K Zheng, Y He, Y Hao, ... Proceedings of the National Academy of Sciences 118 (21), e2013230118, 2021 | 40 | 2021 |
Dissecting the strand folding orientation and formation of G-quadruplexes in single-and double-stranded nucleic acids by ligand-induced photocleavage footprinting K Zheng, D Zhang, L Zhang, Y Hao, X Zhou, Z Tan Journal of the American Chemical Society 133 (5), 1475-1483, 2011 | 40 | 2011 |
Superhelicity constrains a localized and R-loop-dependent formation of G-quadruplexes at the upstream region of transcription K Zheng, Y He, H Liu, X Li, Y Hao, Z Tan ACS chemical biology 12 (10), 2609-2618, 2017 | 35 | 2017 |
Formation of DNA: RNA Hybrid G‐Quadruplexes of Two G‐Quartet Layers in Transcription: Expansion of the Prevalence and Diversity of G‐Quadruplexes in Genomes S Xiao, J Zhang, J Wu, R Wu, Y Xia, K Zheng, Y Hao, X Zhou, Z Tan Angewandte Chemie 126 (48), 13326-13330, 2014 | 34 | 2014 |
Selective targeting of guanine-vacancy-bearing G-quadruplexes by G-quartet complementation and stabilization with a guanine–peptide conjugate Y He, K Zheng, C Wen, X Li, J Gong, Y Hao, Y Zhao, Z Tan Journal of the American Chemical Society 142 (26), 11394-11403, 2020 | 29 | 2020 |
Exceptionally Selective and Tunable Sensing of Guanine Derivatives and Analogues by Structural Complementation in a G‐Quadruplex X Li, K Zheng, Y Hao, Z Tan Angewandte Chemie 128 (44), 13963-13968, 2016 | 29 | 2016 |
Transmission of dynamic supercoiling in linear and multi-way branched DNAs and its regulation revealed by a fluorescent G-quadruplex torsion sensor Y Xia, K Zheng, Y He, H Liu, C Wen, Y Hao, Z Tan Nucleic acids research 46 (14), 7418-7424, 2018 | 20 | 2018 |
RNA G-quadruplex formation in defined sequence in living cells detected by bimolecular fluorescence complementation H Liu, K Zheng, Q Chen, Y Hao, Z Tan Chemical Science 7 (7), 4573-4581, 2016 | 16 | 2016 |