Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors T De Raedt, Z Walton, JL Yecies, D Li, Y Chen, CF Malone, O Maertens, ... Cancer cell 20 (3), 400-413, 2011 | 279 | 2011 |
A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021 | 101 | 2021 |
mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors CF Malone, C Emerson, R Ingraham, W Barbosa, S Guerra, H Yoon, ... Cancer Discovery 7 (12), 1450-1463, 2017 | 98 | 2017 |
Defining Key Signaling Nodes and Therapeutic Biomarkers in NF1-Mutant Cancers CF Malone, JA Fromm, O Maertens, T DeRaedt, R Ingraham, K Cichowski Cancer discovery 4 (9), 1062-1073, 2014 | 65 | 2014 |
Loss of RasGAP tumor suppressors underlies the aggressive nature of luminal B breast cancers SN Olsen, A Wronski, Z Castaño, B Dake, C Malone, T De Raedt, M Enos, ... Cancer discovery 7 (2), 202-217, 2017 | 63 | 2017 |
Selective modulation of a pan-essential protein as a therapeutic strategy in cancer CF Malone, NV Dharia, G Kugener, AB Forman, MV Rothberg, ... Cancer discovery 11 (9), 2282-2299, 2021 | 30 | 2021 |
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ... Nature Cell Biology 25 (2), 285-297, 2023 | 20 | 2023 |
Vincristine and bortezomib cause axon outgrowth and behavioral defects in larval zebrafish TM Khan, N Benaich, CF Malone, RL Bernardos, AR Russell, GB Downes, ... Journal of the Peripheral Nervous System 17 (1), 76-89, 2012 | 18 | 2012 |
Transcriptional antagonism by CDK8 inhibition improves therapeutic efficacy of MEK inhibitors CF Malone, M Kim, G Alexe, K Engel, AB Forman, A Robichaud, ... Cancer research 83 (2), 285-300, 2023 | 7 | 2023 |
Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers. Cancer Discov. 2014; 4: 1062–1073. doi: 10.1158/2159-8290 CF Malone, JA Fromm, O Maertens, T DeRaedt, R Ingraham, K Cichowski CD-14-0159.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 7 | |
Scratching the surface of immunotherapeutic targets in neuroblastoma CF Malone, K Stegmaier Cancer Cell 32 (3), 271-273, 2017 | 6 | 2017 |
An economic study of the dairy enterprise in northeastern Iowa R Buck, J Hopkins, C Malone | 5 | 2017 |
Pharmacological targeting of the cancer epigenome NW Mabe, JA Perry, CF Malone, K Stegmaier Nature Cancer 5 (6), 844-865, 2024 | 2 | 2024 |
Defining a pediatric cancer dependency map NV Dharia, C Malone, AB Iniguez, L Guenther, L Chen, G Alexe, ... Cancer Research 78 (13_Supplement), 2352-2352, 2018 | 1 | 2018 |
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma CF Malone, NW Mabe, AB Forman, G Alexe, KL Engel, YJC Chen, ... Science Advances 10 (22), eadm9449, 2024 | | 2024 |
Targeting CDK8: A translatable therapeutic approach for fusion-positive aRMS S Zhang, C Malone, B Guedes, K Engel, M Just, K Ross, A Fahs, ... Cancer Research 84 (6_Supplement), 5960-5960, 2024 | | 2024 |
CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in MYCN-amplified neuroblastoma CF Malone, NV Dharia, G Kugener, B Paolella, M Rothberg, ... Cancer Research 79 (13_Supplement), 2878-2878, 2019 | | 2019 |
Dairy and hog farming in northeastern Iowa R Buck, J Hopkins, C Malone | | 2017 |
Diverse approaches to developing combination therapies for NF1-mutant cancers CF Malone Harvard University, 2015 | | 2015 |
CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY IN ZEBRAFISH TM Khan, N Benaich, CF Malone, RL Bernardos, AR Russell, MJ Barresi, ... JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 16, S64-S65, 2011 | | 2011 |