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Andrew C. Hsieh
Andrew C. Hsieh
Fred Hutchinson Cancer Center
在 fredhutch.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The translational landscape of mTOR signalling steers cancer initiation and metastasis
AC Hsieh, Y Liu, MP Edlind, NT Ingolia, MR Janes, A Sher, EY Shi, ...
Nature 485 (7396), 55-61, 2012
14492012
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning
N Kondrashov, A Pusic, CR Stumpf, K Shimizu, AC Hsieh, S Xue, ...
Cell 145 (3), 383-397, 2011
6222011
Androgen receptor pathway-independent prostate cancer is sustained through FGF signaling
EG Bluemn, IM Coleman, JM Lucas, RT Coleman, S Hernandez-Lopez, ...
Cancer cell 32 (4), 474-489. e6, 2017
6132017
Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E
AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ...
Cancer cell 17 (3), 249-261, 2010
5362010
Pseudouridylation of tRNA-derived fragments steers translational control in stem cells
N Guzzi, M Cieśla, PCT Ngoc, S Lang, S Arora, M Dimitriou, K Pimková, ...
Cell 173 (5), 1204-1216. e26, 2018
3632018
A library of sirna duplexes targeting the phosphoinositide 3‐kinase pathway: determinants of gene silencing for use in cell‐based screens
AC Hsieh, R Bo, J Manola, F Vazquez, O Bare, A Khvorova, S Scaringe, ...
Nucleic acids research 32 (3), 893-901, 2004
2942004
Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer
MP Labrecque, IM Coleman, LG Brown, LD True, L Kollath, B Lakely, ...
The Journal of clinical investigation 129 (10), 2019
2922019
PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
MP Edlind, AC Hsieh
Asian journal of andrology 16 (3), 378, 2014
2862014
Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer
AC Hsieh, D Ruggero
Clinical cancer research 16 (20), 4914-4920, 2010
2332010
Development of a stress response therapy targeting aggressive prostate cancer
HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ...
Science translational medicine 10 (439), eaar2036, 2018
1472018
Assessing gene-level translational control from ribosome profiling
AB Olshen, AC Hsieh, CR Stumpf, RA Olshen, D Ruggero, BS Taylor
Bioinformatics 29 (23), 2995-3002, 2013
1052013
The untranslated regions of mRNAs in cancer
SL Schuster, AC Hsieh
Trends in cancer, 2019
1012019
MTOR Modulators and Uses Thereof
KM Shokat, D Fruman, P Ren, TE Wilson, L Li, A Hsieh, M Feldman, ...
US Patent App. 13/003,562, 2011
952011
Genomic characterization of prostatic ductal adenocarcinoma identifies a high prevalence of DNA repair gene mutations
MT Schweizer, ES Antonarakis, TA Bismar, LB Guedes, HH Cheng, ...
JCO precision oncology 3, 1-9, 2019
892019
Oncogenic AKTivation of translation as a therapeutic target
AC Hsieh, ML Truitt, D Ruggero
British Journal of Cancer 105 (3), 329-336, 2011
882011
A phase II study of the dual mTOR inhibitor MLN0128 in patients with metastatic castration resistant prostate cancer
L Graham, K Banda, A Torres, BS Carver, Y Chen, K Pisano, G Shelkey, ...
Investigational new drugs 36 (3), 458-467, 2018
742018
The androgen receptor regulates a druggable translational regulon in advanced prostate cancer
Y Liu, JL Horn, K Banda, AZ Goodman, Y Lim, S Jana, S Arora, ...
Science translational medicine 11 (503), eaaw4993, 2019
542019
N 6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
DA Kuppers, S Arora, Y Lim, AR Lim, LM Carter, PD Corrin, CL Plaisier, ...
Nature communications 10 (1), 1-17, 2019
522019
A phase I study of abiraterone acetate combined with BEZ235, a dual PI3K/mTOR inhibitor, in metastatic castration resistant prostate cancer
XX Wei, AC Hsieh, W Kim, T Friedlander, AM Lin, M Louttit, CJ Ryan
The oncologist 22 (5), 503, 2017
512017
Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis
S Jana, AC Hsieh, R Gupta
Cell death & disease 8 (10), e3093-e3093, 2017
452017
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