Genome-wide engineering of an infectious clone of herpes simplex virus type 1 using synthetic genomics assembly methods LM Oldfield, P Grzesik, AA Voorhies, N Alperovich, D MacMath, ... Proceedings of the National Academy of Sciences 114 (42), E8885-E8894, 2017 | 68 | 2017 |
ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity BB Haines, A Denslow, P Grzesik, JS Lee, T Farkaly, J Hewett, ... Cancer Immunology Research 9 (3), 291-308, 2021 | 48 | 2021 |
Efficient size-independent chromosome delivery from yeast to cultured cell lines DM Brown, YA Chan, PJ Desai, P Grzesik, LM Oldfield, S Vashee, JC Way, ... Nucleic acids research 45 (7), e50-e50, 2017 | 41 | 2017 |
Design of an interferon-resistant oncolytic HSV-1 incorporating redundant safety modalities for improved tolerability EM Kennedy, T Farkaly, P Grzesik, J Lee, A Denslow, J Hewett, J Bryant, ... Molecular Therapy-Oncolytics 18, 476-490, 2020 | 19 | 2020 |
Visualization of herpes simplex virus type 1 virions using fluorescent colors L Etienne, P Joshi, L Dingle, E Huang, P Grzesik, PJ Desai Journal of virological methods 241, 46-51, 2017 | 14 | 2017 |
Incorporation of the Kaposi’s sarcoma-associated herpesvirus capsid vertex-specific component (CVSC) into self-assembled capsids P Grzesik, D MacMath, B Henson, S Prasad, P Joshi, PJ Desai Virus research 236, 9-13, 2017 | 8 | 2017 |
Functional Domains of the Herpes Simplex Virus Type 1 Tegument Protein pUL37: The Amino Terminus is Dispensable for Virus Replication in Tissue Culture P Grzesik, EN Pryce, A Bhalala, M Vij, R Ahmed, L Etienne, P Perez, ... Viruses 11 (9), 853, 2019 | 7 | 2019 |
A hydrophobic domain within the small capsid protein of Kaposi’s sarcoma-associated herpesvirus is required for assembly CM Capuano, P Grzesik, D Kreitler, EN Pryce, KV Desai, G Coombs, ... Journal of General Virology 95 (8), 1755-1769, 2014 | 7 | 2014 |
Design of ONCR-177 base vector, a next generation oncolytic herpes simplex virus type-1, optimized for robust oncolysis, transgene expression and tumor-selective replication EM Kennedy, T Farkaly, P Behera, A Colthart, C Goshert, J Jacques, ... Cancer Research 79 (13_Supplement), 1455-1455, 2019 | 5 | 2019 |
Rapid and efficient in vitro excision of BAC sequences from herpesvirus genomes using Cre-mediated recombination P Grzesik, N Ko, LM Oldfield, S Vashee, PJ Desai Journal of virological methods 261, 67-70, 2018 | 2 | 2018 |
EXTH-60. ONCR-GBM, A NOVEL ARMED ONCOLYTIC HSV-1 VECTOR ENGINEERED FOR EFFICACY AND SAFETY IN GLIOBLASTOMA C Strathdee, F Giovannoni, M Molgora, L Kong, M Floyd, J Teng, ... Neuro-Oncology 24 (Suppl 7), vii223, 2022 | 1 | 2022 |
Development of ONCR-NEP, a lipid nanoparticle delivered oncolytic virus capable of robust in situ amplification resulting in tumor lysis and regression. EM Kennedy, JS Lee, J Jacques, T Farkaly, P Behara, P Grzesik, ... Cancer Research 79 (13), 2019 | 1 | 2019 |
mONCR-177 oncolytic virotherapy stimulates anti-tumor and anti-viral immunogenicity M Hayes, A Denslow, J Hewett, D Wambua, L Kong, J Spinale, P Grzesik, ... Cancer Research 80 (16_Supplement), 4572-4572, 2020 | | 2020 |
Abstract B23: microRNA attenuated oHSV-1 armed with multiple immunomodulatory payloads mediates robust and selective antitumor immune response in preclinical tumor models L Lerner, EM Kennedy, T Farkaly, A Colthart, C Montagna, P Behera, ... Cancer Immunology Research 8 (4_Supplement), B23-B23, 2020 | | 2020 |
Abstract B74: Dual mechanism of ONCR-177 enhances antitumor immunogenicity M Hayes, A Denslow, J Gurshaw, D Wambua, S Khatiwada, L Kong, ... Cancer Immunology Research 8 (3_Supplement), B74-B74, 2020 | | 2020 |
ONCR-177, an oncolytic HSV designed to safely and potently activate systemic anti-tumor immunity S Feau, M Hayes, B Haines, A Denslow, J Gursha, D Wambua, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |
Development of ONCR-177, an miR-attenuated oncolytic HSV-1 designed to potently activate systemic antitumor immunity BB Haines, A Denslow, MS Ball, J Gursha, D Wambua, C Kwong, L Kong, ... Cancer Research 79 (13_Supplement), 940-940, 2019 | | 2019 |
Development of ONCR-148, a miRNA-Attenuated Oncolytic HSV-1 Designed to Potently Activate Antitumor T Cell Response A Denslow, BB Haines, MS Ball, J Gursha, D Wambua, C Kwong, L Kong, ... Cancer Research 79 (13), 2019 | | 2019 |
microRNA control of an oHSV vector allows for robust oncolysis and selective control of viral replication in normal tissues EM Kennedy, T Farkaly, C Goshert, A Colthart, P Behera, P Grzesik, ... Cancer Research 78 (13_Supplement), 5929-5929, 2018 | | 2018 |