关注
Yow Keat Tham
Yow Keat Tham
Baker Heart and Diabetes Institute
在 baker.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
YK Tham, BC Bernardo, JYY Ooi, KL Weeks, JR McMullen
Archives of toxicology 89, 1401-1438, 2015
7612015
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
BC Bernardo, XM Gao, CE Winbanks, EJH Boey, YK Tham, H Kiriazis, ...
Proceedings of the National Academy of Sciences 109 (43), 17615-17620, 2012
4782012
Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction
KL Weeks, X Gao, XJ Du, EJH Boey, A Matsumoto, BC Bernardo, ...
Circulation: Heart Failure 5 (4), 523-534, 2012
1392012
Enhanced phosphoinositide 3-kinase (p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes
RH Ritchie, JE Love, K Huynh, BC Bernardo, DC Henstridge, H Kiriazis, ...
Diabetologia 55, 3369-3381, 2012
1002012
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice
G Sapra, YK Tham, N Cemerlang, A Matsumoto, H Kiriazis, BC Bernardo, ...
Nature communications 5 (1), 5705, 2014
952014
Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy
BC Bernardo, XM Gao, YK Tham, H Kiriazis, CE Winbanks, JYY Ooi, ...
PloS one 9 (2), e90337, 2014
832014
Therapeutic silencing of miR‐652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy
BC Bernardo, SS Nguyen, CE Winbanks, XM Gao, EJH Boey, YK Tham, ...
The FASEB Journal 28 (12), 5097-5110, 2014
822014
Inhibition of miR-154 protects against cardiac dysfunction and fibrosis in a mouse model of pressure overload
BC Bernardo, SS Nguyen, XM Gao, YK Tham, JYY Ooi, NL Patterson, ...
Scientific reports 6 (1), 22442, 2016
522016
Lipidomic profiles of the heart and circulation in response to exercise versus cardiac pathology: a resource of potential biomarkers and drug targets
YK Tham, BC Bernardo, K Huynh, JYY Ooi, XM Gao, H Kiriazis, C Giles, ...
Cell reports 24 (10), 2757-2772, 2018
482018
Sex differences in response to miRNA‐34a therapy in mouse models of cardiac disease: identification of sex‐, disease‐and treatment‐regulated miRNAs
BC Bernardo, JYY Ooi, A Matsumoto, YK Tham, S Singla, H Kiriazis, ...
The Journal of physiology 594 (20), 5959-5974, 2016
482016
Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies
YK Tham, K Huynh, NA Mellett, DC Henstridge, H Kiriazis, JYY Ooi, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018
252018
Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling
BC Bernardo, KL Weeks, T Pongsukwechkul, X Gao, H Kiriazis, ...
Clinical Science 132 (3), 381-397, 2018
232018
FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K
KL Weeks, YK Tham, SG Yildiz, Y Alexander, DG Donner, H Kiriazis, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (4 …, 2021
212021
Novel lipid species for detecting and predicting atrial fibrillation in patients with type 2 diabetes
YK Tham, KS Jayawardana, ZH Alshehry, C Giles, K Huynh, AAT Smith, ...
Diabetes 70 (1), 255-261, 2021
122021
Estrogen receptor alpha deficiency in cardiomyocytes reprograms the heart-derived extracellular vesicle proteome and induces obesity in female mice
YK Tham, BC Bernardo, B Claridge, GS Yildiz, LML Woon, S Bond, ...
Nature Cardiovascular Research 2 (3), 268-289, 2023
82023
PI3K (p110α) is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction
USA York, JR McMullen
32012
The therapeutic potential of microRNA-652 for the treatment of heart failure
B Bernardo, X Gao, Y Tham, R Lin, H Kiriazis, X Du, J McMullen
Heart, Lung and Circulation 22, S60, 2013
12013
Cardiac-targeted Delivery of a Novel Inhibitor of Mitochondrial Fission Protein Drp1 (Dynamin-related Protein) for Cardioprotection
J Lees, D Donner, D Rudd, X Lai, T Lin, A Rosdah, S Crawford, A Kong, ...
Heart, Lung and Circulation 32, S408, 2023
2023
Temporal Profiling of Circulating Lipids as Potential Biomarkers in a Mouse Model of Heart Failure and Atrial Fibrillation
Y Tham, T Belkin, A Matsumoto, J Luo, N Mellett, J McMullen
Heart, Lung and Circulation 32, S417-S418, 2023
2023
Alkylglycerol Supplementation Remodels the Cardiac Lipidome and Attenuates Pathological Features in a Mouse Model of Dilated Cardiomyopathy
T Belkin, N Mellet, S Yildiz, E Masterman, P Meikle, Y Tham, J McMullen
Heart, Lung and Circulation 32, S129-S130, 2023
2023
系统目前无法执行此操作,请稍后再试。
文章 1–20