| Characterization of a Cdc42 protein inhibitor and its use as a molecular probe L Hong, SR Kenney, GK Phillips, D Simpson, CE Schroeder, J Nöth, ... Journal of Biological Chemistry 288 (12), 8531-8543, 2013 | 191 | 2013 |
| Advancing biological understanding and therapeutics discovery with small-molecule probes SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ... Cell 161 (6), 1252-1265, 2015 | 175 | 2015 |
| Probe reports from the nih molecular libraries program Z Surviladze, A Waller, JJ Strouse, C Bologa, O Ursu, V Salas, ... Bethesda (MD), 2010 | 170 | 2010 |
| Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction KJ Frankowski, JE Golden, Y Zeng, Y Lei, J Aubé Journal of the American Chemical Society 130 (18), 6018-6024, 2008 | 162 | 2008 |
| Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents RW Bürli, H Xu, X Zou, K Muller, J Golden, M Frohn, M Adlam, MH Plant, ... Bioorganic & medicinal chemistry letters 16 (14), 3713-3718, 2006 | 161 | 2006 |
| Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay RS Adcock, YK Chu, JE Golden, DH Chung Antiviral research 138, 47-56, 2017 | 130 | 2017 |
| A Competitive Nucleotide Binding Inhibitor: In Vitro Characterization of Rab7 GTPase Inhibition JO Agola, L Hong, Z Surviladze, O Ursu, A Waller, JJ Strouse, ... ACS chemical biology 7 (6), 1095-1108, 2012 | 111 | 2012 |
| Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells C Lopez-Sambrooks, S Shrimal, C Khodier, DP Flaherty, N Rinis, ... Nature chemical biology 12 (12), 1023-1030, 2016 | 110 | 2016 |
| A combined intramolecular Diels-Alder/intramolecular Schmidt reaction: Formal synthesis of (+/-)-stenine JE Golden, J Aubé WILEY-V CH VERLAG GMBH, 2002 | 110 | 2002 |
| Facile C− N cleavage in a series of bridged lactams Y Lei, AD Wrobleski, JE Golden, DR Powell, J Aubé Journal of the American Chemical Society 127 (13), 4552-4553, 2005 | 104 | 2005 |
| Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5 VJ Cee, M Frohn, BA Lanman, J Golden, K Muller, S Neira, A Pickrell, ... ACS Medicinal Chemistry Letters 2 (2), 107-112, 2011 | 65 | 2011 |
| Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state DH Chung, JE Golden, RS Adcock, CE Schroeder, YK Chu, JB Sotsky, ... Antimicrobial agents and chemotherapy 60 (8), 4552-4562, 2016 | 60 | 2016 |
| Development of (E)-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of … CE Schroeder, T Yao, J Sotsky, RA Smith, S Roy, YK Chu, H Guo, ... Journal of Medicinal Chemistry 57 (20), 8608-8621, 2014 | 53 | 2014 |
| Discovery of a novel compound with anti-Venezuelan equine encephalitis virus activity that targets the nonstructural protein 2 DH Chung, CB Jonsson, NA Tower, YK Chu, E Sahin, JE Golden, ... PLoS pathogens 10 (6), e1004213, 2014 | 53 | 2014 |
| Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase MT Harris, DM Walker, ME Drew, WG Mitchell, K Dao, CE Schroeder, ... Antimicrobial agents and chemotherapy 57 (8), 3731-3737, 2013 | 50 | 2013 |
| Editing N-glycan site occupancy with small-molecule oligosaccharyltransferase inhibitors N Rinis, JE Golden, CD Marceau, JE Carette, MC Van Zandt, R Gilmore, ... Cell chemical biology 25 (10), 1231-1241. e4, 2018 | 49 | 2018 |
| Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold DP Flaherty, DS Simpson, M Miller, BE Maki, B Zou, J Shi, M Wu, ... Bioorganic & medicinal chemistry letters 24 (16), 3968-3973, 2014 | 47 | 2014 |
| A Pan-GTPase inhibitor as a molecular probe L Hong, Y Guo, S BasuRay, JO Agola, E Romero, DS Simpson, ... PLoS One 10 (8), e0134317, 2015 | 42 | 2015 |
| Discovery of selective inhibitors of endoplasmic reticulum aminopeptidase 1 Z Maben, R Arya, D Rane, WF An, S Metkar, M Hickey, S Bender, A Ali, ... Journal of medicinal chemistry 63 (1), 103-121, 2019 | 40 | 2019 |
| Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1α prolyl hydroxylase-2 inhibitors M Frohn, V Viswanadhan, AJ Pickrell, JE Golden, KM Muller, RW Bürli, ... Bioorganic & medicinal chemistry letters 18 (18), 5023-5026, 2008 | 38 | 2008 |
