关注
Gvido Cebers
Gvido Cebers
Global Head of Non-Clinical Safety, Takeda Pharmaceuticals
在 takeda.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Expression and regulation of the pattern recognition receptors Toll‐like receptor‐2 and Toll‐like receptor‐4 in the human placenta
U Holmlund, G Cebers, AR Dahlfors, B Sandstedt, K Bremme, ...
Immunology 107 (1), 145-151, 2002
3172002
Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease
F Jeppsson, S Eketjäll, J Janson, S Karlström, S Gustavsson, LL Olsson, ...
Journal of Biological Chemistry 287 (49), 41245-41257, 2012
1662012
AZD3293: a novel, orally active BACE1 inhibitor with high potency and permeability and markedly slow off-rate kinetics
S Eketjäll, J Janson, K Kaspersson, A Bogstedt, F Jeppsson, J Fälting, ...
Journal of Alzheimer's Disease 50 (4), 1109-1123, 2016
1502016
AZD3293: pharmacokinetic and pharmacodynamic effects in healthy subjects and patients with Alzheimer’s disease
G Cebers, RC Alexander, SB Haeberlein, D Han, R Goldwater, ...
Journal of Alzheimer's Disease 55 (3), 1039-1053, 2017
1082017
Translocation of dynorphin neuropeptides across the plasma membrane: a putative mechanism of signal transmission
Z Marinova, V Vukojevic, S Surcheva, T Yakovleva, G Cebers, N Pasikova, ...
Journal of Biological Chemistry 280 (28), 26360-26370, 2005
932005
Prodynorphin storage and processing in axon terminals and dendrites
T Yakovleva, I Bazov, G Cebers, Z Marinova, Y Hara, A Ahmed, ...
The FASEB journal 20 (12), 2124-2126, 2006
782006
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue
AH Cluff, B Byström, A Klimaviciute, C Dahlqvist, G Cebers, A Malmström, ...
Reproductive Biology and Endocrinology 4, 1-9, 2006
742006
Cytotoxic effects of dynorphins through nonopioid intracellular mechanisms
K Tan-No, G Cebers, T Yakovleva, BH Goh, I Gileva, K Reznikov, ...
Experimental cell research 269 (1), 54-63, 2001
712001
A μ-receptor opioid agonist induces AP-1 and NF-κB transcription factor activity in primary cultures of rat cortical neurons
YN Hou, M Vlaskovska, G Cebers, L Kasakov, S Liljequist, L Terenius
Neuroscience letters 212 (3), 159-162, 1996
641996
Prodynorphin transcripts and proteins differentially expressed and regulated in the adult human brain
A Nikoshkov, YL Hurd, T Yakovleva, I Bazov, Z Marinova, G Cebers, ...
The FASEB journal 19 (11), 1543-1545, 2005
612005
AMPA neurotoxicity in cultured cerebellar granule neurons: mode of cell death
G Cebers, B Zhivotovsky, M Ankarcrona, S Liljequist
Brain research bulletin 43 (4), 393-403, 1997
531997
Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity
AD Kovács, G Cebers, A Cebere, T Moreira, S Liljequist
Experimental neurology 168 (1), 47-62, 2001
502001
Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto—Kakizaki rats
TJTP Moreira, A Cebere, G Cebers, CG Östenson, S Efendic, S Liljequist
Journal of Cerebral Blood Flow & Metabolism 27 (10), 1710-1723, 2007
472007
Diabetic Goto-Kakizaki rats display pronounced hyperglycemia and longer-lasting cognitive impairments following ischemia induced by cortical compression
T Moreira, G Cebers, C Pickering, CG Östenson, S Efendic, S Liljequist
Neuroscience 144 (4), 1169-1185, 2007
462007
Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551
AR Kosowski, G Cebers, A Cebere, AC Swanhagen, S Liljequist
Psychopharmacology 175, 114-123, 2004
412004
Increased ambient glutamate concentration alters the expression of NMDA receptor subunits in cerebellar granule neurons
G Cebers, A Cebere, AD Kovács, H Högberg, T Moreira, S Liljequist
Neurochemistry international 39 (2), 151-160, 2001
392001
Prolonged inhibition of glutamate reuptake down‐regulates NMDA receptor functions in cultured cerebellar granule cells
G Cebers, A Cebere, A Wägner, S Liljequist
Journal of neurochemistry 72 (5), 2181-2190, 1999
371999
Modulation of AMPA/kainate receptors by cyclothiazide increases cytoplasmic free Ca2+ and 45Ca2+ uptake in brain neurons
G Cebers, S Liljequist
European Journal of Pharmacology: Molecular Pharmacology 290 (2), 105-115, 1995
361995
The NMDA NR2B subunit-selective receptor antagonist, CP-101,606, enhances the functional recovery the NMDA NR2B subunit-selective receptor and reduces brain damage after …
J Kundrotiene, G Cebers, A Wägner, S Liljequist
Journal of neurotrauma 21 (1), 83-93, 2004
352004
Enhancement of NMDA-induced functional responses without concomitant NMDA receptor changes following chronic ethanol exposure in cerebellar granule cells
A Cebere, G Cebers, S Liljequist
Naunyn-Schmiedeberg's archives of pharmacology 360, 623-632, 1999
351999
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