| Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate SF Sleiman, J Henry, R Al-Haddad, L El Hayek, E Abou Haidar, T Stringer, ... elife 5, e15092, 2016 | 799 | 2016 |
| Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF) L El Hayek, M Khalifeh, V Zibara, R Abi Assaad, N Emmanuel, N Karnib, ... Journal of Neuroscience 39 (13), 2369-2382, 2019 | 428 | 2019 |
| Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease SJ McConoughey, M Basso, ZV Niatsetskaya, SF Sleiman, NA Smirnova, ... EMBO molecular medicine 2 (9), 349-370, 2010 | 162 | 2010 |
| Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke RE Speer, SS Karuppagounder, M Basso, SF Sleiman, A Kumar, D Brand, ... Free Radical Biology and Medicine 62, 26-36, 2013 | 154 | 2013 |
| Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration SF Sleiman, BC Langley, M Basso, J Berlin, L Xia, JB Payappilly, ... Journal of Neuroscience 31 (18), 6858-6870, 2011 | 140 | 2011 |
| Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models SS Karuppagounder, I Alim, SJ Khim, MW Bourassa, SF Sleiman, R John, ... Science translational medicine 8 (328), 328ra29-328ra29, 2016 | 134 | 2016 |
| Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases N Karnib, R El-Ghandour, L El Hayek, P Nasrallah, M Khalifeh, N Barmo, ... Neuropsychopharmacology 44 (6), 1152-1162, 2019 | 116 | 2019 |
| Putting the ‘HAT’back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions SF Sleiman, M Basso, L Mahishi, AP Kozikowski, ME Donohoe, B Langley, ... Expert opinion on investigational drugs 18 (5), 573-584, 2009 | 94 | 2009 |
| Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells G Bkaily, S Sleiman, J Stephan, C Asselin, S Choufani, M Kamal, ... Canadian journal of physiology and pharmacology 81 (3), 274-287, 2003 | 88 | 2003 |
| Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation M Basso, J Berlin, L Xia, SF Sleiman, B Ko, R Haskew-Layton, E Kim, ... Journal of Neuroscience 32 (19), 6561-6569, 2012 | 78 | 2012 |
| Epigenetic changes in diabetes R Al-Haddad, N Karnib, R Abi Assaad, Y Bilen, N Emmanuel, A Ghanem, ... Neuroscience letters 625, 64-69, 2016 | 70 | 2016 |
| Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling P Nasrallah, E Abou Haidar, JS Stephan, L El Hayek, N Karnib, ... Neurobiology of stress 11, 100170, 2019 | 58 | 2019 |
| Downstream consequences of exercise through the action of BDNF SF Sleiman, MV Chao Brain Plasticity 1 (1), 143-148, 2015 | 46 | 2015 |
| Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism DE Olson, SF Sleiman, MW Bourassa, FF Wagner, JP Gale, YL Zhang, ... Chemistry & biology 22 (4), 439-445, 2015 | 43 | 2015 |
| Epigenetics of Alzheimer's disease and frontotemporal dementia CS Veerappan, S Sleiman, G Coppola Neurotherapeutics 10 (4), 709-721, 2013 | 40 | 2013 |
| Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition SF Sleiman, DE Olson, MW Bourassa, SS Karuppagounder, YL Zhang, ... Journal of Neuroscience 34 (43), 14328-14337, 2014 | 34 | 2014 |
| Histone deacetylase inhibitors and mithramycin A impact a similar neuroprotective pathway at a crossroad between cancer and neurodegeneration SF Sleiman, J Berlin, M Basso, S S. Karuppagounder, J Rohr, RR Ratan Pharmaceuticals 4 (8), 1183-1195, 2011 | 27 | 2011 |
| Antihelminthic Benzimidazoles Are Novel HIF Activators That Prevent Oxidative Neuronal Death via Binding to Tubulin H Aleyasin, SS Karuppagounder, A Kumar, S Sleiman, M Basso, T Ma, ... Antioxidants & redox signaling 22 (2), 121-134, 2015 | 26 | 2015 |
| Exercise factors as potential mediators of cognitive rehabilitation following traumatic brain injury JS Stephan, SF Sleiman Current opinion in neurology 32 (6), 808-814, 2019 | 24 | 2019 |
| Exercise factors released by the liver, muscle, and bones have promising therapeutic potential for stroke JS Stephan, SF Sleiman Frontiers in neurology 12, 600365, 2021 | 20 | 2021 |
