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Shalini Gupta
Shalini Gupta
在 iacs.res.in 的电子邮件经过验证
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Self-transfecting GMO-PMO chimera targeting Nanog enable gene silencing in vitro and suppresses tumor growth in 4T1 allografts in mouse
U Das, J Kundu, P Shaw, C Bose, A Ghosh, S Gupta, S Sarkar, J Bhadra, ...
Molecular Therapy-Nucleic Acids 32, 203-228, 2023
72023
Morpholino oligonucleotide-mediated exon skipping for DMD treatment: Past insights, present challenges and future perspectives
S Gupta, SN Sharma, J Kundu, S Pattanayak, S Sinha
Journal of Biosciences 48 (4), 38, 2023
62023
Guanidinium-functionalized flexible azaproline transporter for efficient intracellular delivery of proapoptotic peptide and PDL1 antisense morpholino oligo in human carcinoma …
A Gupta, S Gupta, U Das, S Sinha
Bioconjugate Chemistry 33 (5), 907-917, 2022
62022
Structural modifications to the internal oligoguanidinium transporter uncover two potent analogues that effectively deliver the proapoptotic peptide in multiple cancer cell lines
S Gupta, M Qasim, A Gupta, J Kundu, S Sinha
Bioconjugate Chemistry 33 (1), 121-133, 2021
62021
4′-C-Acetamidomethyl-2′-O-methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small …
S Gangopadhyay, G Das, S Gupta, A Ghosh, SS Bagale, PK Roy, ...
The Journal of Organic Chemistry 89 (6), 3747-3768, 2024
22024
Synthesis of Self Permeable Antisense PMO Using C5-Guanidino-Functionalized Pyrimidines at the 5′-End Enables Sox2 Downregulation in Triple Negative Breast Cancer Cells
A Das, S Gupta, P Shaw, S Sinha
Molecular Pharmaceutics 21 (3), 1256-1271, 2024
22024
Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro
U Ghosh, S Gupta, S Sinha
Bioconjugate Chemistry 34 (1), 174-180, 2022
22022
Evaluation of a Tubulin‐Targeted Pyrimidine Indole Hybrid Molecule as an Anticancer Agent
C Bose, P Banerjee, J Kundu, B Dutta, I Ghosh, S Sinha, A Ghosh, ...
ChemistrySelect 5 (44), 14021-14031, 2020
22020
Total Synthesis of Lipopeptide Bacilotetrin C: Discovery of Potent Anticancer Congeners Promoting Autophagy
SS Auddy, S Gupta, S Mandi, H Sharma, S Sinha, RK Goswami
ACS Medicinal Chemistry Letters 15 (8), 1340-1350, 2024
2024
2′-O-Alkyl-N3-Methyluridine Functionalized Passenger Strand Improves RNAi Activity by Modulating the Thermal Stability
A Sahoo, S Gupta, G Das, A Ghosh, SS Bagale, S Sinha, KR Gore
ACS Medicinal Chemistry Letters 15 (8), 1250-1259, 2024
2024
Benzofuran Iboga‐analogs Modulate Nociception and Inflammation in an Acute Mouse Pain Model
T Bhattacharya, A Gupta, S Gupta, S Saha, S Ghosh, Z Shireen, S Dey, ...
ChemBioChem, e202400162, 2024
2024
IGT mediated Nanog siRNA delivery in prostate cancer cells improves chemosensitization of Epirubicin in vitro
S Gupta, U Das, S Sinha
Bioorganic & Medicinal Chemistry Letters 76, 129017, 2022
2022
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