Persistent epigenetic differences associated with prenatal exposure to famine in humans BT Heijmans, EW Tobi, AD Stein, H Putter, GJ Blauw, ES Susser, ... Proceedings of the National Academy of Sciences 105 (44), 17046-17049, 2008 | 3598 | 2008 |
DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific EW Tobi, LH Lumey, RP Talens, D Kremer, H Putter, AD Stein, ... Human molecular genetics 18 (21), 4046-4053, 2009 | 1326 | 2009 |
DNA methylation signatures link prenatal famine exposure to growth and metabolism EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ... Nature communications 5 (1), 5592, 2014 | 608 | 2014 |
Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology RP Talens, DI Boomsma, EW Tobi, D Kremer, JW Jukema, G Willemsen, ... The FASEB Journal 24 (9), 3135-3144, 2010 | 369 | 2010 |
The epigenome: archive of the prenatal environment BT Heijmans, EW Tobi, LH Lumey, PE Slagboom Epigenetics 4 (8), 526-531, 2009 | 309 | 2009 |
Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus BT Heijmans, D Kremer, EW Tobi, DI Boomsma, PE Slagboom Human molecular genetics 16 (5), 547-554, 2007 | 298 | 2007 |
DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood EW Tobi, RC Slieker, R Luijk, KF Dekkers, AD Stein, KM Xu, ... Science advances 4 (1), eaao4364, 2018 | 273 | 2018 |
MethylAid: visual and interactive quality control of large Illumina 450k datasets M Van Iterson, EW Tobi, RC Slieker, W Den Hollander, R Luijk, ... Bioinformatics 30 (23), 3435-3437, 2014 | 172 | 2014 |
Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19 EW Tobi, PE Slagboom, J Van Dongen, D Kremer, AD Stein, H Putter, ... PloS one 7 (5), e37933, 2012 | 171 | 2012 |
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome EW Tobi, RC Slieker, AD Stein, HED Suchiman, PE Slagboom, ... International journal of epidemiology 44 (4), 1211-1223, 2015 | 170 | 2015 |
DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age EW Tobi, BT Heijmans, D Kremer, H Putter, HA Delemarre-van de Waal, ... Epigenetics 6 (2), 171-176, 2011 | 167 | 2011 |
Duration of breastfeeding and gender are associated with methylation of the LEPTIN gene in very young children SA Obermann-Borst, PHC Eilers, EW Tobi, FH de Jong, PE Slagboom, ... Pediatric research 74 (3), 344-349, 2013 | 136 | 2013 |
Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis N Bomer, W den Hollander, YFM Ramos, SD Bos, R van der Breggen, ... Annals of the rheumatic diseases 74 (8), 1571-1579, 2015 | 101 | 2015 |
DNA methylation landscapes of human fetal development RC Slieker, MS Roost, L van Iperen, HED Suchiman, EW Tobi, F Carlotti, ... PLoS genetics 11 (10), e1005583, 2015 | 96 | 2015 |
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER HED Suchiman, RC Slieker, D Kremer, PE Slagboom, BT Heijmans, ... Frontiers in genetics 6, 287, 2015 | 95 | 2015 |
Epigenetic signature of birth weight discordance in adult twins Q Tan, M Frost, BT Heijmans, J von Bornemann Hjelmborg, EW Tobi, ... BMC genomics 15, 1-9, 2014 | 57 | 2014 |
Tea and coffee consumption in relation to DNA methylation in four European cohorts WE Ek, EW Tobi, M Ahsan, E Lampa, E Ponzi, SA Kyrtopoulos, ... Human molecular genetics 26 (16), 3221-3231, 2017 | 48 | 2017 |
The effect of the Chinese Famine on type 2 diabetes mellitus epidemics C Li, EW Tobi, BT Heijmans, LH Lumey Nature Reviews Endocrinology 15 (6), 313-314, 2019 | 38 | 2019 |
Selective survival of embryos can explain DNA methylation signatures of adverse prenatal environments EW Tobi, J van den Heuvel, BJ Zwaan, LH Lumey, BT Heijmans, T Uller Cell Reports 25 (10), 2660-2667. e4, 2018 | 33 | 2018 |
Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes PE Thijssen, EW Tobi, J Balog, SG Schouten, D Kremer, F El Bouazzaoui, ... Epigenetics 8 (5), 512-521, 2013 | 30 | 2013 |