| Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers PM Brown, AG Pratt, JD Isaacs Nature Reviews Rheumatology 12 (12), 731, 2016 | 407 | 2016 |
| Synovial tissue research: a state-of-the-art review C Orr, E Vieira-Sousa, DL Boyle, MH Buch, CD Buckley, JD Cañete, ... Nature Reviews Rheumatology 13 (8), 463, 2017 | 258 | 2017 |
| Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open … F Humby, P Durez, MH Buch, MJ Lewis, H Rizvi, F Rivellese, A Nerviani, ... The Lancet 397 (10271), 305-317, 2021 | 205 | 2021 |
| What are the dominant cytokines in early rheumatoid arthritis? LA Ridgley, AE Anderson, AG Pratt Current opinion in rheumatology 30 (2), 207, 2018 | 169 | 2018 |
| Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis F Penkava, MDC Velasco-Herrera, MD Young, N Yager, LN Nwosu, ... Nature communications 11 (1), 1-11, 2020 | 126 | 2020 |
| Current concepts in the pathogenesis of early rheumatoid arthritis AG Pratt, JD Isaacs, DL Mattey Best Practice & Research Clinical Rheumatology 23 (1), 37-48, 2009 | 124 | 2009 |
| Clinical Utility of Random Anti–Tumor Necrosis Factor Drug–Level Testing and Measurement of Antidrug Antibodies on the Long‐Term Treatment Response in Rheumatoid Arthritis M Jani, H Chinoy, RB Warren, CEM Griffiths, D Plant, B Fu, AW Morgan, ... Arthritis & rheumatology 67 (8), 2011-2019, 2015 | 113 | 2015 |
| Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis G Reynolds, JR Gibbon, AG Pratt, MJ Wood, D Coady, G Raftery, ... Annals of the rheumatic diseases 75 (5), 899-907, 2016 | 103 | 2016 |
| Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical … M Al-Laith, M Jasenecova, S Abraham, A Bosworth, IN Bruce, CD Buckley, ... Trials 20 (1), 1-15, 2019 | 101 | 2019 |
| Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23 A McGovern, S Schoenfelder, P Martin, J Massey, K Duffus, D Plant, ... Genome biology 17 (1), 212, 2016 | 99 | 2016 |
| Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients MJ Wood, A Leckenby, G Reynolds, R Spiering, AG Pratt, KS Rankin, ... JCI insight 4 (2), 2019 | 97 | 2019 |
| Seronegative rheumatoid arthritis: pathogenetic and therapeutic aspects AG Pratt, JD Isaacs Best Practice & Research Clinical Rheumatology 28 (4), 651-659, 2014 | 90 | 2014 |
| A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease AG Pratt, DC Swan, S Richardson, G Wilson, CMU Hilkens, DA Young, ... Annals of the rheumatic diseases 71 (8), 1374-1381, 2012 | 87 | 2012 |
| IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis AE Anderson, AG Pratt, MAK Sedhom, JP Doran, C Routledge, ... Annals of the rheumatic diseases 75 (2), 466-473, 2016 | 80 | 2016 |
| Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor‐β1 AE Anderson, DJ Swan, OY Wong, M Buck, O Eltherington, RA Harry, ... Clinical & Experimental Immunology 187 (1), 113-123, 2017 | 76 | 2017 |
| Determination of thymic function directly from peripheral blood: a validated modification to an established method AR Lorenzi, AM Patterson, A Pratt, M Jefferson, CE Chapman, F Ponchel, ... Journal of immunological methods 339 (2), 185-194, 2008 | 76 | 2008 |
| Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study … A Abhishek, RJ Boyton, N Peckham, Á McKnight, LC Coates, J Bluett, ... The Lancet Respiratory Medicine 10 (9), 840-850, 2022 | 68 | 2022 |
| Use of the QuantiFERON TB Gold test as part of a screening programme in patients with RA under consideration for treatment with anti-TNF-α agents: the Newcastle (UK) experience A Pratt, K Nicholl, L Kay Oxford University Press 46 (6), 1035-1036, 2007 | 57 | 2007 |
| The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy FAH Cooles, AE Anderson, DW Lendrem, J Norris, AG Pratt, CMU Hilkens, ... Journal of Allergy and Clinical Immunology 141 (1), 445-448. e4, 2018 | 52 | 2018 |
| CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification N Thalayasingam, N Nair, AJ Skelton, J Massey, AE Anderson, AD Clark, ... Arthritis & Rheumatology 70 (3), 361-370, 2018 | 51 | 2018 |
