Selective COX-1 inhibition: A therapeutic target to be reconsidered M G Perrone, A Scilimati, L Simone, P Vitale Current medicinal chemistry 17 (32), 3769-3805, 2010 | 193 | 2010 |
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors P Vitale, S Tacconelli, MG Perrone, P Malerba, L Simone, A Scilimati, ... Journal of Medicinal Chemistry 56 (11), 4277-4299, 2013 | 99 | 2013 |
Translational readthrough generates new astrocyte AQP4 isoforms that modulate supramolecular clustering, glial endfeet localization, and water transport M De Bellis, F Pisani, MG Mola, S Rosito, L Simone, C Buccoliero, ... Glia 65 (5), 790-803, 2017 | 77 | 2017 |
Glio-vascular modifications caused by Aquaporin-4 deletion in the mouse retina GP Nicchia, F Pisani, L Simone, A Cibelli, MG Mola, M Dal Monte, ... Experimental Eye Research 146, 259-268, 2016 | 51 | 2016 |
AQP4 aggregation state is a determinant for glioma cell fate L Simone, F Pisani, MG Mola, M De Bellis, G Merla, L Micale, A Frigeri, ... Cancer research 79 (9), 2182-2194, 2019 | 45 | 2019 |
Stereoselective dimerization of 3-arylisoxazoles to cage-shaped bis-β-lactams syn 2, 6-diaryl-3, 7-diazatricyclo [4.2. 0.02, 5] octan-4, 8-diones induced by hindered lithium amides L Di Nunno, P Vitale, A Scilimati, L Simone, F Capitelli Tetrahedron 63 (50), 12388-12395, 2007 | 38 | 2007 |
Identification of a point mutation impairing the binding between aquaporin-4 and neuromyelitis optica autoantibodies F Pisani, MG Mola, L Simone, S Rosito, D Alberga, GF Mangiatordi, ... Journal of Biological Chemistry 289 (44), 30578-30589, 2014 | 27 | 2014 |
Aquaporin‐1 inhibition reduces metastatic formation in a mouse model of melanoma L Simone, CD Gargano, F Pisani, A Cibelli, MG Mola, A Frigeri, M Svelto, ... Journal of Cellular and Molecular Medicine 22 (2), 904-912, 2018 | 26 | 2018 |
Role of pericytes in blood–brain barrier preservation during ischemia through tunneling nanotubes F Pisani, V Castagnola, L Simone, F Loiacono, M Svelto, F Benfenati Cell Death & Disease 13 (7), 582, 2022 | 24 | 2022 |
Regulation of aquaporin‐4 expression in the central nervous system investigated using M23‐AQP4 null mouse F Pisani, L Simone, MG Mola, M De Bellis, A Frigeri, GP Nicchia, M Svelto Glia 69 (9), 2235-2251, 2021 | 14 | 2021 |
AQP4-dependent glioma cell features affect the phenotype of surrounding cells via extracellular vesicles L Simone, F Pisani, E Binda, A Frigeri, AL Vescovi, M Svelto, GP Nicchia Cell & Bioscience 12 (1), 1-17, 2022 | 4 | 2022 |
Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles—New Insights for Structural and Functional Studies F Pisani, L Simone, MG Mola, M De Bellis, M Mastrapasqua, M Ruggieri, ... Cells 8 (2), 119, 2019 | 4 | 2019 |
GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria L Simone, DL Capobianco, F Di Palma, E Binda, FG Legnani, AL Vescovi, ... Frontiers in Cell and Developmental Biology 11, 2023 | 3 | 2023 |
Role of the H-bond between L53 and T56 for Aquaporin-4 epitope in Neuromyelitis Optica F Pisani, L Simone, CD Gargano, M De Bellis, A Cibelli, MG Mola, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (3), 368-376, 2017 | 3 | 2017 |
Tunneling Nanotubes Connect Blood-Brain Barrier Cells: Role of Pericytes in Barrier Preservation During Ischemia F Pisani, V Castagnola, L Simone, F Loiacono, M Svelto, F Benfenati bioRxiv, 2022.03. 02.482668, 2022 | 2 | 2022 |
Intercellular crosstalk mediated by tunneling nanotubes between central nervous system cells. What we need to advance DL Capobianco, L Simone, M Svelto, F Pisani Frontiers in Physiology 14, 2023 | 1 | 2023 |
Vesicles-mediated release of AQP4 from glioblastoma cells: a communication mechanism? L Simone, F Pisani, A Frigeri, M Svelto, AL Vescovi, E Binda, GP Nicchia ACTA PHYSIOLOGICA 227, 158-159, 2019 | | 2019 |
Orthogonal Arrays of Particles alter cytoskeleton and cell invasion dynamics in GBM and glioma cells GP Nicchia, L Simone, MG Mola, F Pisani, CD Gargano, A Frigeri, ... Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018 | | 2018 |
Translational readthrough generates new astrocyte AQP4 isoforms that modulate supramolecular clustering, glial endfeet localization, and water transport M DE BELLIS, F Pisani, MG Mola, S Rosito, L Simone, C Buccoliero, ... GLIA 65 (5), 790-803, 2017 | | 2017 |
Highly selective COX-1 inhibitors as novel cardioprotective anti-thrombotic agents MG Perrone, L Simone, P Vitale, L DI NUNNO, A Scilimati, A Lavecchia, ... XXIII Congresso Nazionale della Società Chimica Italiana-Atti del congresso, 2009 | | 2009 |