| Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice SJ Alexopoulos, SY Chen, AE Brandon, JM Salamoun, FL Byrne, ... Nature Communications 11 (1), 2397, 2020 | 96 | 2020 |
| Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme E Jentho, C Ruiz-Moreno, B Novakovic, I Kourtzelis, WL Megchelenbrink, ... Proceedings of the National Academy of Sciences 118 (42), e2102698118, 2021 | 73 | 2021 |
| PI3K signaling in the pathogenesis of obesity: The cause and the cure M Beretta, M Bauer, E Hirsch Advances in biological regulation 58, 1-15, 2015 | 49 | 2015 |
| Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH–dependent sympathetic drive A Perino, M Beretta, A Kilić, A Ghigo, D Carnevale, IE Repetto, L Braccini, ... Science signaling 7 (352), ra110-ra110, 2014 | 42 | 2014 |
| 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis JM Salamoun, CJ Garcia, SR Hargett, JH Murray, SY Chen, M Beretta, ... Journal of medicinal chemistry 63 (11), 6203-6224, 2020 | 26 | 2020 |
| Targeted delivery of a phosphoinositide 3‐kinase γ inhibitor to restore organ function in sepsis AT Press, P Babic, B Hoffmann, T Müller, W Foo, W Hauswald, J Benecke, ... EMBO Molecular Medicine 13 (10), e14436, 2021 | 24 | 2021 |
| Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano [3, 4-b] pyrazine BAM15 ERM Zunica, CL Axelrod, E Cho, G Spielmann, G Davuluri, ... Cancer & Metabolism 9, 1-20, 2021 | 20 | 2021 |
| Ether lipid and sphingolipid expression patterns are estrogen receptor-dependently altered in breast cancer cells L Hahnefeld, L Gruber, N Schömel, C Fischer, P Mattjus, R Gurke, ... The international journal of biochemistry & cell biology 127, 105834, 2020 | 17 | 2020 |
| Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake SY Chen, M Beretta, SJ Alexopoulos, DP Shah, EM Olzomer, SR Hargett, ... Metabolism 117, 154724, 2021 | 14 | 2021 |
| Oxadiazolopyridine derivatives as efficacious mitochondrial uncouplers in the prevention of diet-induced obesity JH Murray, AL Burgio, M Beretta, SR Hargett, TE Harris, E Olzomer, ... Journal of medicinal chemistry 66 (6), 3876-3895, 2023 | 11 | 2023 |
| Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice SY Chen, M Beretta, EM Olzomer, DP Shah, DYH Wong, SJ Alexopoulos, ... Molecular metabolism 69, 101684, 2023 | 10 | 2023 |
| Heme induces innate immune memory E Jentho, B Novakovic, C Ruiz-Moreno, I Kourtzelis, R Martins, ... BioRxiv, 2019.12. 12.874578, 2019 | 10 | 2019 |
| Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis AJ Beer, D Hertz, E Seemann, M Beretta, M Westermann, R Bauer, ... Scientific Reports 10 (1), 13110, 2020 | 6 | 2020 |
| Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice M Beretta, Y Dai, EM Olzomer, CS Vancuylenburg, JA Santiago-Rivera, ... Diabetes 73 (3), 374-384, 2024 | 5 | 2024 |
| Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice SY Chen, M Beretta, EM Olzomer, SJ Alexopoulos, DP Shah, FL Byrne, ... Biochimica et biophysica acta. Molecular basis of disease 1870 (1), 166908, 2023 | 3 | 2023 |
| Investigating the Expression and Function of the Glucose Transporter GLUT6 in Obesity SY Chen, EM Olzomer, M Beretta, J Cantley, CS Nunemaker, KL Hoehn, ... International Journal of Molecular Sciences 23 (17), 9798, 2022 | 3 | 2022 |
| Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis through dye-functionalized lipid nanocarriers AT Press, P Babic, B Hoffmann, T Müller, W Foo, W Hauswald, J Benecke, ... bioRxiv, 2021.01. 20.427305, 2021 | 3 | 2021 |
| Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice SY Chen, AJ Telfser, EM Olzomer, CS Vancuylenberg, M Zhou, M Beretta, ... Clinical Science 138 (4), 173-187, 2024 | 1 | 2024 |
| Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase RA Clarke, H Govindaraju, M Beretta, E Olzomer, AJ Lawther, AK Walker, ... International Journal of Molecular Sciences 25 (2), 990, 2024 | 1 | 2024 |
| Cell-type specific role of phosphoinositide 3-kinase γ in inflammatory-induced cholestasis M Beretta | 1 | 2018 |
