Structural and functional differences between glycosylated and non-glycosylated forms of human interferon-β (IFN-β) L Runkel, W Meier, RB Pepinsky, M Karpusas, A Whitty, K Kimball, ... Pharmaceutical research 15, 641-649, 1998 | 413 | 1998 |
The crystal structure of human interferon β at 2.2-Å resolution M Karpusas, M Nolte, CB Benton, W Meier, WN Lipscomb, S Goelz Proceedings of the National Academy of Sciences 94 (22), 11813-11818, 1997 | 331 | 1997 |
2 Å crystal structure of an extracellular fragment of human CD40 ligand M Karpusas, YM Hsu, J Wang, J Thompson, S Lederman, L Chess, ... Structure 3 (10), 1031-1039, 1995 | 330 | 1995 |
Hydrophobic packing in T4 Lysozyme probed by cavity-filling mutants BWM M Karpusas, WA Baase, M Matsumura Proceedings of the National Academy of Sciences, 1989 | 218 | 1989 |
Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes M Karpusas, TG Cachero, F Qian, A Boriack-Sjodin, C Mullen, K Strauch, ... Journal of molecular biology 315 (5), 1145-1154, 2002 | 181 | 2002 |
The structure of human interferon-β: implications for activity M Karpusas, A Whitty, L Runkel, P Hochman Cellular and Molecular Life Sciences CMLS 54, 1203-1216, 1998 | 169 | 1998 |
Proposed mechanism for the condensation reaction of citrate synthase: 1.9-. ANG. structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A M Karpusas, B Branchaud, SJ Remington Biochemistry 29 (9), 2213-2219, 1990 | 162 | 1990 |
The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 CD loop can inhibit VCAM-1 … JH Wang, RB Pepinsky, T Stehle, J Liu, M Karpusas, B Browning, ... Proceedings of the National Academy of Sciences 92 (12), 5714-5718, 1995 | 152 | 1995 |
Systematic mutational mapping of sites on human interferon-β-1a that are important for receptor binding and functional activity L Runkel, C deDios, M Karpusas, M Betzenhauser, C Muldowney, ... Biochemistry 39 (10), 2538-2551, 2000 | 117 | 2000 |
The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain. EJ Collins, DN Garboczi, MN Karpusas, DC Wiley Proceedings of the National Academy of Sciences 92 (4), 1218-1221, 1995 | 102 | 1995 |
The role of polar interactions in the molecular recognition of CD40L with its receptor CD40 J Singh, E Garber, HV Vlijmen, M Karpusas, YM Hsu, Z Zheng, D Thomas, ... Protein science 7 (5), 1124-1135, 1998 | 98 | 1998 |
Crystal structure of the α1β1 integrin I-domain: insights into integrin I-domain function M Nolte, RB Pepinsky, SY Venyaminov, V Koteliansky, PJ Gotwals, ... FEBS letters 452 (3), 379-385, 1999 | 96 | 1999 |
Analysis of imatinib and sorafenib binding to p38α compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG … HV Namboodiri, M Bukhtiyarova, J Ramcharan, M Karpusas, Y Lee, ... Biochemistry 49 (17), 3611-3618, 2010 | 86 | 2010 |
Antibodies to VLA-1 PD Lyne, EA Garber, JW Saldanha, M Karpusas US Patent 7,358,054, 2008 | 86 | 2008 |
1.9-. ANG. Structures of ternary complexes of citrate synthase with D-and L-malate: mechanistic implications M Karpusas, D Holland, SJ Remington Biochemistry 30 (24), 6024-6031, 1991 | 80 | 1991 |
Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression GI Lambrou, S Vlahopoulos, C Papathanasiou, M Papanikolaou, ... Leukemia research 33 (12), 1684-1695, 2009 | 68 | 2009 |
Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody M Karpusas, J Lucci, J Ferrant, C Benjamin, FR Taylor, K Strauch, ... Structure 9 (4), 321-329, 2001 | 68 | 2001 |
Improved expression, purification, and crystallization of p38α MAP kinase M Bukhtiyarova, K Northrop, X Chai, D Casper, M Karpusas, E Springman Protein expression and purification 37 (1), 154-161, 2004 | 59 | 2004 |
Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-. ANG. resolution DI Liao, M Karpusas, SJ Remington Biochemistry 30 (24), 6031-6036, 1991 | 55 | 1991 |
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the … I Zaganas, C Spanaki, M Karpusas, A Plaitakis Journal of Biological Chemistry 277 (48), 46552-46558, 2002 | 49 | 2002 |