| Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis F Iovino, CJ Orihuela, HE Moorlag, G Molema, JJE Bijlsma PloS one 8 (7), e68408, 2013 | 110 | 2013 |
| pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion F Iovino, JY Engelen-Lee, M Brouwer, D van de Beek, A van der Ende, ... Journal of Experimental Medicine 214 (6), 1619-1630, 2017 | 101 | 2017 |
| Immunomodulatory effects of pneumococcal extracellular vesicles on cellular and humoral host defenses M Codemo, S Muschiol, F Iovino, P Nannapaneni, L Plant, SN Wai, ... MBio 9 (2), 10.1128/mbio. 00559-18, 2018 | 86 | 2018 |
| How does Streptococcus pneumoniae invade the brain? F Iovino, J Seinen, B Henriques-Normark, JM van Dijl Trends in microbiology 24 (4), 307-315, 2016 | 85 | 2016 |
| Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA F Iovino, DL Hammarlöf, G Garriss, S Brovall, P Nannapaneni, ... The Journal of clinical investigation 126 (8), 2821-2826, 2016 | 52 | 2016 |
| Signalling or binding: The role of the platelet‐activating factor receptor in invasive pneumococcal disease F Iovino, MC Brouwer, D van de Beek, G Molema, JJE Bijlsma Cellular microbiology 15 (6), 870-881, 2013 | 52 | 2013 |
| Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier F Iovino, G Molema, JJE Bijlsma Infection and immunity 82 (9), 3555-3566, 2014 | 51 | 2014 |
| Streptococcus pneumoniae Invades Endothelial Host Cells via Multiple Pathways and Is Killed in a Lysosome Dependent Manner H Gradstedt, F Iovino, JJE Bijlsma PloS one 8 (6), e65626, 2013 | 49 | 2013 |
| Streptococcus pneumoniae Interacts with pIgR Expressed by the Brain Microvascular Endothelium but Does Not Co-Localize with PAF Receptor F Iovino, G Molema, JJE Bijlsma PLoS One 9 (5), e97914, 2014 | 44 | 2014 |
| The role of microglia in bacterial meningitis: inflammatory response, experimental models and new neuroprotective therapeutic strategies S Thorsdottir, B Henriques-Normark, F Iovino Frontiers in microbiology 10, 442622, 2019 | 33 | 2019 |
| Neuronal damage and neuroinflammation, a bridge between bacterial meningitis and neurodegenerative diseases K Farmen, M Tofiño-Vian, F Iovino Frontiers in Cellular Neuroscience 15, 680858, 2021 | 32 | 2021 |
| Luminescent CeO2: Eu3+ nanocrystals for robust in situ H2O2 real-time detection in bacterial cell cultures DF Henning, P Merkl, C Yun, F Iovino, L Xie, E Mouzourakis, C Moularas, ... Biosensors and Bioelectronics 132, 286-293, 2019 | 26 | 2019 |
| Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin M Tabusi, S Thorsdottir, M Lysandrou, AR Narciso, M Minoia, ... PLoS pathogens 17 (3), e1009432, 2021 | 23 | 2021 |
| Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease K Subramanian, F Iovino, V Tsikourkitoudi, P Merkl, S Ahmed, SB Berry, ... EMBO molecular medicine 12 (11), e12695, 2020 | 23 | 2020 |
| Receptor blockade: a novel approach to protect the brain from pneumococcal invasion F Iovino, S Thorsdottir, B Henriques-Normark The Journal of infectious diseases 218 (3), 476-484, 2018 | 22 | 2018 |
| The impact of the ancillary pilus‐1 protein RrgA of Streptococcus pneumoniae on colonization and disease F Iovino, P Nannapaneni, B Henriques‐Normark, S Normark Molecular microbiology 113 (3), 650-658, 2020 | 15 | 2020 |
| The proteasome-ubiquitin system is required for efficient killing of intracellular Streptococcus pneumoniae by brain endothelial cells F Iovino, H Gradstedt, JJ Bijlsma MBio 5 (4), 10.1128/mbio. 00984-14, 2014 | 15 | 2014 |
| Immunomodulatory effects of pneumococcal extracellular vesicles on cellular and humoral host defenses. mBio 9: e00559-18 M Codemo, S Muschiol, F Iovino, P Nannapaneni, L Plant, SN Wai, ... | 13 | 2018 |
| Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA AR Narciso, F Iovino, S Thorsdottir, P Mellroth, M Codemo, C Spoerry, ... Proceedings of the National Academy of Sciences 119 (23), e2122386119, 2022 | 12 | 2022 |
| Bacterial meningitis in Africa T Barichello, CH Rocha Catalão, UK Rohlwink, M Kuip, D Zaharie, ... Frontiers in neurology 14, 822575, 2023 | 11 | 2023 |
