Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ A Casiraghi, L Suigo, E Valoti, V Straniero Antibiotics 9 (2), 69, 2020 | 68 | 2020 |
Benzodioxane–benzamides as new bacterial cell division inhibitors G Chiodini, M Pallavicini, C Zanotto, M Bissa, A Radaelli, V Straniero, ... European journal of medicinal chemistry 89, 252-265, 2015 | 52 | 2015 |
Predicting the physicochemical profile of diastereoisomeric histidine‐containing dipeptides by property space analysis G Vistoli, V Straniero, A Pedretti, L Fumagalli, C Bolchi, M Pallavicini, ... Chirality 24 (7), 566-576, 2012 | 44 | 2012 |
3-(Benzodioxan-2-ylmethoxy)-2, 6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and … V Straniero, M Pallavicini, G Chiodini, C Zanotto, L Volontè, A Radaelli, ... European journal of medicinal chemistry 120, 227-243, 2016 | 33 | 2016 |
6-Methoxy-7-benzofuranoxy and 6-Methoxy-7-indolyloxy Analogues of 2-[2-(2, 6-Dimethoxyphenoxy) ethyl] aminomethyl-1, 4-benzodioxane (WB4101): 1 Discovery of a Potent and … L Fumagalli, M Pallavicini, R Budriesi, C Bolchi, M Canovi, A Chiarini, ... Journal of medicinal chemistry 56 (16), 6402-6412, 2013 | 32 | 2013 |
One-pot racemization process of 1-phenyl-1, 2, 3, 4-tetrahydroisoquinoline: A key intermediate for the antimuscarinic agent solifenacin C Bolchi, M Pallavicini, L Fumagalli, V Straniero, E Valoti Organic Process Research & Development 17 (3), 432-437, 2013 | 31 | 2013 |
Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate G Faustini, F Longhena, A Bruno, F Bono, J Grigoletto, L La Via, A Barbon, ... Neurobiology of disease 138, 104789, 2020 | 30 | 2020 |
Benzodioxane‐benzamides as antibacterial agents: computational and SAR studies to evaluate the influence of the 7‐substitution in FtsZ interaction V Straniero, V Sebastián‐Pérez, M Hrast, C Zanotto, A Casiraghi, L Suigo, ... ChemMedChem 15 (2), 195-209, 2020 | 28 | 2020 |
2, 6‐Difluorobenzamide Inhibitors of Bacterial Cell Division Protein FtsZ: Design, Synthesis, and Structure–Activity Relationships V Straniero, C Zanotto, L Straniero, A Casiraghi, S Duga, A Radaelli, ... ChemMedChem 12 (16), 1303-1318, 2017 | 26 | 2017 |
Benzamide derivatives targeting the cell division protein FtsZ: modifications of the linker and the benzodioxane scaffold and their effects on antimicrobial activity V Straniero, L Suigo, A Casiraghi, V Sebastián-Pérez, M Hrast, C Zanotto, ... Antibiotics 9 (4), 160, 2020 | 24 | 2020 |
Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents G Vistoli, D De Maddis, V Straniero, A Pedretti, M Pallavicini, E Valoti, ... European Journal of Medicinal Chemistry 66, 153-160, 2013 | 24 | 2013 |
Affinity and activity profiling of unichiral 8-substituted 1, 4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist L Fumagalli, M Pallavicini, R Budriesi, M Gobbi, V Straniero, M Zagami, ... European journal of medicinal chemistry 58, 184-191, 2012 | 24 | 2012 |
From 2-aminomethyl-1, 4-benzodioxane enantiomers to unichiral 2-cyano-and 2-carbonyl-substituted benzodioxanes via dichloroamine C Bolchi, E Valoti, V Straniero, P Ruggeri, M Pallavicini The Journal of Organic Chemistry 79 (14), 6732-6737, 2014 | 21 | 2014 |
Thiazole-and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase C Bolchi, M Pallavicini, SK Bernini, G Chiodini, A Corsini, N Ferri, ... Bioorganic & medicinal chemistry letters 21 (18), 5408-5412, 2011 | 21 | 2011 |
Oral bioavailability and pharmacokinetics of nonanimal chondroitin sulfate and its constituents in healthy male volunteers N Volpi, V Mantovani, F Galeotti, D Bianchi, V Straniero, E Valoti, ... Clinical Pharmacology in Drug Development 8 (3), 336-345, 2019 | 20 | 2019 |
Farnesyltransferase inhibitors: CAAX mimetics based on different biaryl scaffolds V Straniero, M Pallavicini, G Chiodini, P Ruggeri, L Fumagalli, C Bolchi, ... Bioorganic & Medicinal Chemistry Letters 24 (13), 2924-2927, 2014 | 19 | 2014 |
Identification of 1-butyl-3-(1-(4-methyl) naphtoyl) indole detected for the first time in “herbal high” products on the Italian market E Valoti, E Casagni, L Dell’Acqua, M Pallavicini, G Roda, C Rusconi, ... Forensic Science International 223 (1-3), e42-e46, 2012 | 19 | 2012 |
Computational design and development of benzodioxane-benzamides as potent inhibitors of FtsZ by exploring the hydrophobic subpocket V Straniero, V Sebastián-Pérez, L Suigo, W Margolin, A Casiraghi, ... Antibiotics 10 (4), 442, 2021 | 15 | 2021 |
How do reaction conditions affect the enantiopure synthesis of 2‐substituted‐1, 4‐benzodioxane derivatives? V Straniero, A Casiraghi, L Fumagalli, E Valoti Chirality 30 (7), 943-950, 2018 | 14 | 2018 |
Stressed degradation studies of domiphen bromide by LC-ESI-MS/MS identify a novel promising antimicrobial agent L Fumagalli, LG Regazzoni, V Straniero, E Valoti, G Aldini, G Vistoli, ... Journal of Pharmaceutical and Biomedical Analysis 159, 224-228, 2018 | 13 | 2018 |