A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment A Balestrini, V Joseph, M Dourado, RM Reese, SD Shields, L Rougé, ... Journal of Experimental Medicine 218 (4), 2021 | 102 | 2021 |
Insensitivity to pain upon adult-onset deletion of Nav1. 7 or its blockade with selective inhibitors SD Shields, L Deng, RM Reese, M Dourado, J Tao, O Foreman, ... Journal of Neuroscience 38 (47), 10180-10201, 2018 | 85 | 2018 |
A non-covalent ligand reveals biased agonism of the TRPA1 ion channel C Liu, R Reese, S Vu, L Rougé, SD Shields, S Kakiuchi-Kiyota, H Chen, ... Neuron 109 (2), 273-284. e4, 2021 | 75 | 2021 |
Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma RM Reese, M Dourado, K Anderson, S Warming, KL Stark, A Balestrini, ... Scientific reports 10 (1), 979, 2020 | 54 | 2020 |
Discovery of a Potent (4R,5S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug … H Chen, M Volgraf, S Do, A Kolesnikov, DG Shore, VA Verma, E Villemure, ... Journal of Medicinal Chemistry 61 (8), 3641-3659, 2018 | 44 | 2018 |
Tetrahydrofuran-based transient receptor potential ankyrin 1 (TRPA1) antagonists: ligand-based discovery, activity in a rodent asthma model, and mechanism-of-action via … JA Terrett, H Chen, DG Shore, E Villemure, R Larouche-Gauthier, M Dery, ... Journal of Medicinal Chemistry 64 (7), 3843-3869, 2021 | 41 | 2021 |
Intrinsic and Extrinsic Factors Governing the Transcriptional Regulation of ESR1 DK Lung, RM Reese, ET Alarid Hormones and Cancer 11 (3), 129-147, 2020 | 40 | 2020 |
The phosphorylated estrogen receptor α (ER) cistrome identifies a subset of active enhancers enriched for direct ER-DNA binding and the transcription factor GRHL2 KT Helzer, MS Ozers, MB Meyer, NA Benkusky, N Solodin, RM Reese, ... Molecular and cellular biology, 2019 | 36 | 2019 |
Grainyhead-like protein 2: the emerging role in hormone-dependent cancers and epigenetics RM Reese, MM Harrison, ET Alarid Endocrinology 160 (5), 1275-1288, 2019 | 32 | 2019 |
Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310 BS Safina, SJ McKerrall, S Sun, CA Chen, S Chowdhury, Q Jia, J Li, ... Journal of medicinal chemistry 64 (6), 2953-2966, 2021 | 26 | 2021 |
Nav1. 7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids L Deng, M Dourado, RM Reese, K Huang, SD Shields, KL Stark, ... Neuron 111 (17), 2642-2659. e13, 2023 | 24 | 2023 |
Altered patterning of trisomy 21 interneuron progenitors Y Giffin-Rao, J Sheng, B Strand, K Xu, L Huang, M Medo, KA Risgaard, ... Stem Cell Reports 17 (6), 1366-1379, 2022 | 22 | 2022 |
A retrospective look at the impact of binding site environment on the optimization of TRPA1 antagonists E Villemure, JA Terrett, R Larouche-Gauthier, M Dery, H Chen, RM Reese, ... ACS Medicinal Chemistry Letters 12 (8), 1230-1237, 2021 | 15 | 2021 |
GRHL2 enhances phosphorylated estrogen receptor (ER) chromatin binding and regulates ER-mediated transcriptional activation and repression RM Reese, KT Helzer, KO Allen, C Zheng, N Solodin, ET Alarid Molecular and Cellular Biology, 2022 | 9 | 2022 |
Altered patterning of interneuron progenitors in Down syndrome Y Giffin-Rao, B Strand, M Medo, A Keshan, RA Daley Jr, S Mohan, ... bioRxiv, 2020.02. 18.951756, 2020 | 2 | 2020 |
Progesterone Receptor–Mediated Regulation of Cellular Glucose and 18F-Fluorodeoxyglucose Uptake in Breast Cancer K Salem, RM Reese, ET Alarid, AM Fowler Journal of the Endocrine Society 7 (2), bvac186, 2023 | 1 | 2023 |
GRHL2 enhances phosphorylated estrogen receptor DNA-binding and regulates ER-mediated transcriptional activation and repression RM Reese, KT Helzer, KO Allen, C Zheng, N Solodin, ET Alarid bioRxiv, 2022.05. 19.492733, 2022 | 1 | 2022 |
THU491 GRHL2 Overexpression In Breast Cancer Progression C Zheng, KO Allen, R Reese, NM Solodin, J Vera, S Mcilwain, T Liu, ... Journal of the Endocrine Society 7 (Supplement_1), bvad114. 2119, 2023 | | 2023 |
Grainyhead-Like Protein 2 Regulates the Transcriptional Activity of Estrogen Receptor Alpha Phosphorylated at Serine 118 in Breast Cancer RM Reese The University of Wisconsin-Madison, 2022 | | 2022 |
The Transcriptional Function of GRHL2 in Hormone-Dependent Breast Cancers R Reese, K Helzer, ET Alarid Journal of the Endocrine Society 5 (Suppl 1), A819, 2021 | | 2021 |