| BET bromodomain inhibition as a therapeutic strategy to target c-Myc JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi, HM Jacobs, E Kastritis, ... Cell 146 (6), 904-917, 2011 | 3222 | 2011 |
| Transcriptional amplification in tumor cells with elevated c-Myc CY Lin, J Lovén, PB Rahl, RM Paranal, CB Burge, JE Bradner, TI Lee, ... Cell 151 (1), 56-67, 2012 | 1700 | 2012 |
| NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis JD Brown, CY Lin, Q Duan, G Griffin, AJ Federation, RM Paranal, S Bair, ... Molecular cell 56 (2), 219-231, 2014 | 625 | 2014 |
| BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia CJ Ott, N Kopp, L Bird, RM Paranal, J Qi, T Bowman, SJ Rodig, AL Kung, ... Blood, The Journal of the American Society of Hematology 120 (14), 2843-2852, 2012 | 468 | 2012 |
| Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition O Weigert, AA Lane, L Bird, N Kopp, B Chapuy, D van Bodegom, ... Journal of experimental medicine 209 (2), 259-273, 2012 | 174 | 2012 |
| Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma T Hideshima, J Qi, RM Paranal, W Tang, E Greenberg, N West, ... Proceedings of the National Academy of Sciences 113 (46), 13162-13167, 2016 | 140 | 2016 |
| Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation SM Frumm, ZP Fan, KN Ross, JR Duvall, S Gupta, L VerPlank, BC Suh, ... Chemistry & biology 20 (5), 713-725, 2013 | 118 | 2013 |
| Synthesis and biological evaluation of JAHAs: ferrocene-based histone deacetylase inhibitors J Spencer, J Amin, M Wang, G Packham, SSS Alwi, GJ Tizzard, SJ Coles, ... ACS medicinal chemistry letters 2 (5), 358-362, 2011 | 103 | 2011 |
| Development of a potent and selective HDAC8 inhibitor OJ Ingham, RM Paranal, WB Smith, RA Escobar, H Yueh, T Snyder, ... ACS medicinal chemistry letters 7 (10), 929-932, 2016 | 78 | 2016 |
| C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors L Barroilhet, J Yang, K Hasselblatt, RM Paranal, SK Ng, JA Rauh-Hain, ... Oncogene 32 (33), 3896-3903, 2013 | 50 | 2013 |
| Click JAHAs: conformationally restricted ferrocene-based histone deacetylase inhibitors J Spencer, J Amin, R Boddiboyena, G Packham, BE Cavell, SSS Alwi, ... MedChemComm 3 (1), 61-64, 2012 | 50 | 2012 |
| Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs JM Guerra-Bubb, AA Bowers, WB Smith, R Paranal, G Estiu, O Wiest, ... Bioorganic & medicinal chemistry letters 23 (21), 6025-6028, 2013 | 38 | 2013 |
| The oral manifestations of syphilitic disease: a case report KL Streight, RM Paranal, DM Musher Journal of medical case reports 13, 1-3, 2019 | 26 | 2019 |
| Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors H Patel, I Chuckowree, P Coxhead, M Guille, M Wang, A Zuckermann, ... MedChemComm 5 (12), 1829-1833, 2014 | 25 | 2014 |
| Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects CT Chan, J Qi, W Smith, R Paranol, R Mazitschek, N West, R Reeves, ... Cancer research 74 (24), 7475-7486, 2014 | 12 | 2014 |
| Impact of luteinizing hormone suppression on hematopoietic recovery after intensive chemotherapy in patients with leukemia I Abou Dalle, R Paranal, J Zarka, S Paul, K Sasaki, W Li, J Ning, NJ Short, ... Haematologica 106 (4), 1097, 2020 | 10 | 2020 |
| A cyclodextrin-capped histone deacetylase inhibitor J Amin, A Puglisi, J Clarke, J Milton, M Wang, RM Paranal, JE Bradner, ... Bioorganic & medicinal chemistry letters 23 (11), 3346-3348, 2013 | 10 | 2013 |
| Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag S Henikoff, JG Henikoff, K Ahmad, RM Paranal, DH Janssens, ZR Russell, ... Nature Communications 14 (1), 5930, 2023 | 9 | 2023 |
| RNA Polymerase II hypertranscription in cancer FFPE samples S Henikoff, JG Henikoff, RM Paranal, JE Greene, Y Zheng, ZR Russell, ... bioRxiv, 2024 | 2 | 2024 |
| BET Bromodomain Inhibition Targets Both c-Myc and IL7R in Acute Lymphoblastic Leukemia N Kopp, CJ Ott, L Bird, R Paranal, J Qi, T Bowman, SJ Rodig, AL Kung, ... Blood 120 (21), 672, 2012 | 2 | 2012 |
