NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes DA Elliott, SR Braam, K Koutsis, ES Ng, R Jenny, EL Lagerqvist, C Biben, ... Nature methods 8 (12), 1037-1040, 2011 | 518 | 2011 |
Embryonic stem cells as a source of models for drug discovery CW Pouton, JM Haynes Nature Reviews Drug Discovery 6 (8), 605-616, 2007 | 244 | 2007 |
Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy LM Kaminskas, VM McLeod, GM Ryan, BD Kelly, JM Haynes, ... Journal of Controlled Release 183, 18-26, 2014 | 213 | 2014 |
Transcriptional signature in microglia associated with Aβ plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature communications 12 (1), 3015, 2021 | 186 | 2021 |
Facile One‐Step Micropatterning Using Photodegradable Gelatin Hydrogels for Improved Cardiomyocyte Organization and Alignment KMC Tsang, N Annabi, F Ercole, K Zhou, DJ Karst, F Li, JM Haynes, ... Advanced functional materials 25 (6), 977-986, 2015 | 128 | 2015 |
A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives AL Goulburn, D Alden, RP Davis, SJ Micallef, ES Ng, QC Yu, SM Lim, ... Stem cells 29 (3), 462-473, 2011 | 123 | 2011 |
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network DJ Anderson, DI Kaplan, KM Bell, K Koutsis, JM Haynes, RJ Mills, ... Nature communications 9 (1), 1373, 2018 | 112 | 2018 |
Novel drug targets for the pharmacotherapy of benign prostatic hyperplasia (BPH) S Ventura, VL Oliver, CW White, JH Xie, JM Haynes, B Exintaris British journal of pharmacology 163 (5), 891-907, 2011 | 111 | 2011 |
Pharmaceutical applications of embryonic stem cells CW Pouton, JM Haynes Advanced Drug Delivery Reviews 57 (13), 1918-1934, 2005 | 99 | 2005 |
SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development RJP Skelton, M Costa, DJ Anderson, F Bruveris, BW Finnin, K Koutsis, ... Stem cell research 13 (1), 172-179, 2014 | 86 | 2014 |
Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices Q Chen, L Jin, WD Cook, D Mohn, EL Lagerqvist, DA Elliott, JM Haynes, ... Soft Matter 6 (19), 4715-4726, 2010 | 84 | 2010 |
Chronic stress and A lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia A Milligan Armstrong, T Porter, H Quek, A White, J Haynes, C Jackaman, ... Biological Reviews 96 (5), 2209-2228, 2021 | 69 | 2021 |
Acute or delayed systemic administration of human amnion epithelial cells improves outcomes in experimental stroke MA Evans, R Lim, HA Kim, HX Chu, CV Gardiner-Mann, KWE Taylor, ... Stroke 49 (3), 700-709, 2018 | 69 | 2018 |
Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells ALM Cook, JM Haynes Cellular signalling 16 (2), 253-261, 2004 | 67 | 2004 |
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous … LM Kaminskas, VM McLeod, DB Ascher, GM Ryan, S Jones, JM Haynes, ... Molecular pharmaceutics 12 (2), 432-443, 2015 | 63 | 2015 |
Adrenomedullin and calcitonin gene-related peptide in the rat isolated kidney and in the anaesthetised rat: in vitro and in vivo effects JM Haynes, ME Cooper European journal of pharmacology 280 (1), 91-94, 1995 | 61 | 1995 |
Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under xeno-free conditions restore motor deficits in parkinsonian rodents JC Niclis, CW Gantner, WF Alsanie, SJ McDougall, CR Bye, AG Elefanty, ... Stem cells translational medicine 6 (3), 937-948, 2017 | 59 | 2017 |
Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines JC Niclis, A Pinar, JM Haynes, W Alsanie, R Jenny, M Dottori, DS Cram Frontiers in cellular neuroscience 7, 37, 2013 | 45 | 2013 |
PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance … LJ Chan, JB Bulitta, DB Ascher, JM Haynes, VM McLeod, CJH Porter, ... Molecular pharmaceutics 12 (3), 794-809, 2015 | 40 | 2015 |
Three-dimensional differentiation of human pluripotent stem cell-derived neural precursor cells using tailored porous polymer scaffolds AR Murphy, JM Haynes, AL Laslett, NR Cameron, CM O'Brien Acta Biomaterialia 101, 102-116, 2020 | 38 | 2020 |