The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease J Sevigny, P Chiao, T Bussière, PH Weinreb, L Williams, M Maier, ... Nature 537 (7618), 50-56, 2016 | 3009 | 2016 |
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded PH Weinreb, W Zhen, AW Poon, KA Conway, PT Lansbury Biochemistry 35 (43), 13709-13715, 1996 | 1944 | 1996 |
Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases LEN Quadri, PH Weinreb, M Lei, MM Nakano, P Zuber, CT Walsh Biochemistry 37 (6), 1585-1595, 1998 | 812 | 1998 |
Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin LEN Quadri, J Sello, TA Keating, PH Weinreb, CT Walsh Chemistry & biology 5 (11), 631-645, 1998 | 553 | 1998 |
Partial inhibition of integrin αvβ6 prevents pulmonary fibrosis without exacerbating inflammation GS Horan, S Wood, V Ona, DJ Li, ME Lukashev, PH Weinreb, KJ Simon, ... American journal of respiratory and critical care medicine 177 (1), 56-65, 2008 | 471 | 2008 |
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by β-amyloid: is NAC a common trigger or target in neurodegenerative disease? H Han, PH Weinreb, PT Lansbury Jr Chemistry & biology 2 (3), 163-169, 1995 | 417 | 1995 |
The αvβ6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle P Monaghan, S Gold, J Simpson, Z Zhang, PH Weinreb, SM Violette, ... Journal of General Virology 86 (10), 2769-2780, 2005 | 408 | 2005 |
Stromal features are predictive of disease mortality in oral cancer patients D Marsh, K Suchak, KA Moutasim, S Vallath, C Hopper, W Jerjes, T Upile, ... The Journal of pathology 223 (4), 470-481, 2011 | 371 | 2011 |
Post-translational modification of polyketide and nonribosomal peptide synthases CT Walsh, AM Gehring, PH Weinreb, LEN Quadri, RS Flugel Current opinion in chemical biology 1 (3), 309-315, 1997 | 320 | 1997 |
Inhibition of integrin αvβ6, an activator of latent transforming growth factor-β, prevents radiation-induced lung fibrosis K Puthawala, N Hadjiangelis, SC Jacoby, E Bayongan, Z Zhao, Z Yang, ... American journal of respiratory and critical care medicine 177 (1), 82-90, 2008 | 310 | 2008 |
Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β JW Arndt, F Qian, BA Smith, C Quan, KP Kilambi, MW Bush, T Walz, ... Scientific reports 8 (1), 6412, 2018 | 266 | 2018 |
Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice P Aluwihare, Z Mu, Z Zhao, D Yu, PH Weinreb, GS Horan, SM Violette, ... Journal of cell science 122 (2), 227-232, 2009 | 255 | 2009 |
Interleukin-1β causes acute lung injury via αvβ5 and αvβ6 integrin–dependent mechanisms MT Ganter, J Roux, B Miyazawa, M Howard, JA Frank, G Su, D Sheppard, ... Circulation research 102 (7), 804-812, 2008 | 253 | 2008 |
Lysophosphatidic acid induces αvβ6 integrin-mediated TGF-β activation via the LPA2 receptor and the small G protein Gαq MY Xu, J Porte, AJ Knox, PH Weinreb, TM Maher, SM Violette, ... The American journal of pathology 174 (4), 1264-1279, 2009 | 246 | 2009 |
αvβ6 integrin regulates renal fibrosis and inflammation in Alport mouse K Hahm, ME Lukashev, Y Luo, WJ Yang, BM Dolinski, PH Weinreb, ... The American journal of pathology 170 (1), 110-125, 2007 | 236 | 2007 |
Obtustatin: A Potent Selective Inhibitor of α1β1 Integrin in Vitro and Angiogenesis in Vivo C Marcinkiewicz, PH Weinreb, JJ Calvete, DG Kisiel, SA Mousa, ... Cancer research 63 (9), 2020-2023, 2003 | 211 | 2003 |
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin β6 J Azare, K Leslie, H Al-Ahmadie, W Gerald, PH Weinreb, SM Violette, ... Molecular and cellular biology 27 (12), 4444-4453, 2007 | 210 | 2007 |
Overexpression of the αvβ6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival S Hazelbag, GG Kenter, A Gorter, EJ Dreef, LA Koopman, SM Violette, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007 | 207 | 2007 |
Enhanced potency of human Sonic hedgehog by hydrophobic modification FR Taylor, D Wen, EA Garber, AN Carmillo, DP Baker, RM Arduini, ... Biochemistry 40 (14), 4359-4371, 2001 | 204 | 2001 |
Function-blocking integrin αvβ6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes PH Weinreb, KJ Simon, P Rayhorn, WJ Yang, DR Leone, BM Dolinski, ... Journal of Biological Chemistry 279 (17), 17875-17887, 2004 | 185 | 2004 |