Production of the antimalarial drug precursor artemisinic acid in engineered yeast DK Ro, EM Paradise, M Ouellet, KJ Fisher, KL Newman, JM Ndungu, ... Nature 440 (7086), 940-943, 2006 | 3518 | 2006 |
High-level semi-synthetic production of the potent antimalarial artemisinin CJ Paddon, PJ Westfall, DJ Pitera, K Benjamin, K Fisher, D McPhee, ... Nature 496 (7446), 528-532, 2013 | 2234 | 2013 |
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids VJJ Martin, DJ Pitera, ST Withers, JD Newman, JD Keasling Nature biotechnology 21 (7), 796-802, 2003 | 2211 | 2003 |
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass EJ Steen, Y Kang, G Bokinsky, Z Hu, A Schirmer, A McClure, ... Nature 463 (7280), 559-562, 2010 | 1595 | 2010 |
Synthetic protein scaffolds provide modular control over metabolic flux JE Dueber, GC Wu, GR Malmirchegini, TS Moon, CJ Petzold, AV Ullal, ... Nature biotechnology 27 (8), 753-759, 2009 | 1393 | 2009 |
Microbial engineering for the production of advanced biofuels PP Peralta-Yahya, F Zhang, SB Del Cardayre, JD Keasling Nature 488 (7411), 320-328, 2012 | 1247 | 2012 |
Engineering cellular metabolism J Nielsen, JD Keasling Cell 164 (6), 1185-1197, 2016 | 1185 | 2016 |
Manufacturing molecules through metabolic engineering JD Keasling Science 330 (6009), 1355-1358, 2010 | 962 | 2010 |
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids F Zhang, JM Carothers, JD Keasling Nature biotechnology 30 (4), 354-359, 2012 | 929 | 2012 |
Precise and reliable gene expression via standard transcription and translation initiation elements VK Mutalik, JC Guimaraes, G Cambray, C Lam, MJ Christoffersen, QA Mai, ... Nature methods 10 (4), 354-360, 2013 | 850 | 2013 |
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin PJ Westfall, DJ Pitera, JR Lenihan, D Eng, FX Woolard, R Regentin, ... Proceedings of the National Academy of Sciences 109 (3), E111-E118, 2012 | 818 | 2012 |
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development CJ Paddon, JD Keasling Nature reviews microbiology 12 (5), 355-367, 2014 | 783 | 2014 |
Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels SK Lee, H Chou, TS Ham, TS Lee, JD Keasling Current opinion in biotechnology 19 (6), 556-563, 2008 | 753 | 2008 |
Identification and microbial production of a terpene-based advanced biofuel PP Peralta-Yahya, M Ouellet, R Chan, A Mukhopadhyay, JD Keasling, ... Nature communications 2 (1), 483, 2011 | 649 | 2011 |
Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol EJ Steen, R Chan, N Prasad, S Myers, CJ Petzold, A Redding, M Ouellet, ... Microbial cell factories 7, 1-8, 2008 | 648 | 2008 |
Complete biosynthesis of cannabinoids and their unnatural analogues in yeast X Luo, MA Reiter, L d’Espaux, J Wong, CM Denby, A Lechner, Y Zhang, ... Nature 567 (7746), 123-126, 2019 | 624 | 2019 |
Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes BF Pfleger, DJ Pitera, CD Smolke, JD Keasling Nature biotechnology 24 (8), 1027-1032, 2006 | 618 | 2006 |
Engineering microbial biofuel tolerance and export using efflux pumps MJ Dunlop, ZY Dossani, HL Szmidt, HC Chu, TS Lee, JD Keasling, ... Molecular systems biology 7 (1), 487, 2011 | 592 | 2011 |
Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli DJ Pitera, CJ Paddon, JD Newman, JD Keasling Metabolic engineering 9 (2), 193-207, 2007 | 539 | 2007 |
Designed divergent evolution of enzyme function Y Yoshikuni, TE Ferrin, JD Keasling Nature 440 (7087), 1078-1082, 2006 | 537 | 2006 |