| Thousands of chemical starting points for antimalarial lead identification FJ Gamo, LM Sanz, J Vidal, C De Cozar, E Alvarez, JL Lavandera, ... Nature 465 (7296), 305-310, 2010 | 1192 | 2010 |
| Fueling open‐source drug discovery: 177 small‐molecule leads against tuberculosis L Ballell, RH Bates, RJ Young, D Alvarez‐Gomez, E Alvarez‐Ruiz, ... ChemMedChem 8 (2), 313-321, 2013 | 375 | 2013 |
| Cheminformatic models to predict binding affinities to human serum albumin G Colmenarejo, A Alvarez-Pedraglio, JL Lavandera Journal of medicinal chemistry 44 (25), 4370-4378, 2001 | 329 | 2001 |
| Three‐dimensional cryo‐electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution MG Gomez‐Lorenzo, CMT Spahn, RK Agrawal, RA Grassucci, P Penczek, ... The EMBO journal, 2000 | 202 | 2000 |
| Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity A Cameron, J Read, R Tranter, VJ Winter, RB Sessions, RL Brady, ... Journal of Biological Chemistry 279 (30), 31429-31439, 2004 | 188 | 2004 |
| Structure-guided discovery of phenyl-diketo acids as potent inhibitors of M. tuberculosis malate synthase IV Krieger, JS Freundlich, VB Gawandi, JP Roberts, VB Gawandi, Q Sun, ... Chemistry & biology 19 (12), 1556-1567, 2012 | 130 | 2012 |
| Synthesis and physicochemical studies on 1, 2‐bisazolylethanes J Torres, JL Lavandera, P Cabildo, RM Claramunt, J Elguero Journal of heterocyclic chemistry 25 (3), 771-782, 1988 | 108 | 1988 |
| Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives ML López-Rodríguez, E Porras, MJ Morcillo, B Benhamú, LJ Soto, ... Journal of medicinal chemistry 46 (26), 5638-5650, 2003 | 98 | 2003 |
| An invitation to open innovation in malaria drug discovery: 47 quality starting points from the TCAMS F Calderón, D Barros, JM Bueno, JM Coterón, E Fernández, FJ Gamo, ... ACS Medicinal Chemistry Letters 2 (10), 741-746, 2011 | 94 | 2011 |
| Curcumin and curcuminoids: chemistry, structural studies and biological properties J González-Albadalejo, D Sanz, RM Claramunt, JL Lavandera, I Alkorta, ... An. Real Acad. Nac. Farm 81, 278-310, 2015 | 87 | 2015 |
| Translation elongation factor 2 is part of the target for a new family of antifungals L Capa, A Mendoza, JL Lavandera, F Gómez de las Heras, ... Antimicrobial agents and chemotherapy 42 (10), 2694-2699, 1998 | 84 | 1998 |
| First pharmacophoric hypothesis for 5-HT7 antagonism ML López-Rodrı́guez, E Porras, B Benhamú, JA Ramos, MJ Morcillo, ... Bioorganic & Medicinal Chemistry Letters 10 (10), 1097-1100, 2000 | 80 | 2000 |
| Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor M Martínez-Hoyos, E Perez-Herran, G Gulten, L Encinas, ... EBioMedicine 8, 291-301, 2016 | 72 | 2016 |
| IGF-I increases markers of osteoblastic activity and reduces bone resorption via osteoprotegerin and RANK-ligand L Guerra-Menéndez, MC Sádaba, JE Puche, JL Lavandera, LF de Castro, ... Journal of translational medicine 11, 1-12, 2013 | 69 | 2013 |
| Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase L Vivas, A Easton, H Kendrick, A Cameron, JL Lavandera, D Barros, ... Experimental parasitology 111 (2), 105-114, 2005 | 64 | 2005 |
| Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs D Blanco, E Perez-Herran, M Cacho, L Ballell, J Castro, ... Antimicrobial Agents and Chemotherapy 59 (4), 1868-1875, 2015 | 52 | 2015 |
| Optimization of the separation of a group of antifungals by capillary zone electrophoresis AL Crego, ML Marina, JL Lavandera Journal of Chromatography A 917 (1-2), 337-345, 2001 | 50 | 2001 |
| Potent antimalarial 4-pyridones with improved physico-chemical properties JM Bueno, P Manzano, MC García, J Chicharro, M Puente, M Lorenzo, ... Bioorganic & medicinal chemistry letters 21 (18), 5214-5218, 2011 | 46 | 2011 |
| Carbonic anhydrase activators. VII. Isozyme II activation by bisazolyl-methanes,-ethanes and related azoles CT Supuran, AT Balaban, P Cabildo, RM Claramunt, JL LAvANDERA, ... Biological and Pharmaceutical Bulletin 16 (12), 1236-1239, 1993 | 43 | 1993 |
| Carbonic Anhydrase Activators. XV. A Kinetic Study of the Interaction of Bovine Isozyme II with Pyrazoles, Bis-and Tris-azolyl-methanse CT SUPURAN, RM Claramunt, JL LAvANDERA, J Elguero Biological and Pharmaceutical Bulletin 19 (11), 1417-1422, 1996 | 40 | 1996 |
