| Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization: biochemical and … S Chen, L Chen, J Tan, J Chen, L Du, T Sun, J Shen, K Chen, H Jiang, ... Journal of Biological Chemistry 280 (1), 164-173, 2005 | 107 | 2005 |
| Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal L Du, YJ Li, M Fakih, RL Wiatrek, M Duldulao, Z Chen, P Chu, ... Nature communications 7 (1), 12326, 2016 | 104 | 2016 |
| D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75 L Du, Y Zhao, J Chen, L Yang, Y Zheng, Y Tang, X Shen, H Jiang Biochemical and biophysical research communications 375 (1), 139-144, 2008 | 99 | 2008 |
| Structural basis for catalytic and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) L Zhang, W Liu, T Hu, L Du, C Luo, K Chen, X Shen, H Jiang Journal of Biological Chemistry 283 (9), 5370-5379, 2008 | 82 | 2008 |
| Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease L Du, M Bergsneider, L Mirsadraei, SH Young, JW Jonker, M Downes, ... Proceedings of the National Academy of Sciences 110 (21), 8555-8560, 2013 | 70 | 2013 |
| Regulation of adipose differentiation by fructose and GluT5 L Du, AP Heaney Molecular endocrinology 26 (10), 1773-1782, 2012 | 69 | 2012 |
| Allosteric inhibition of ubiquitin-like modifications by a class of inhibitor of SUMO-activating enzyme YJ Li, L Du, J Wang, R Vega, TD Lee, Y Miao, G Aldana-Masangkay, ... Cell chemical biology 26 (2), 278-288. e6, 2019 | 48 | 2019 |
| Hyrtiosal, from the Marine Sponge Hyrtios erectus, Inhibits HIV‐1 Integrase Binding to Viral DNA by a New Inhibitor Binding Site L Du, L Shen, Z Yu, J Chen, Y Guo, Y Tang, X Shen, H Jiang ChemMedChem: Chemistry Enabling Drug Discovery 3 (1), 173-180, 2008 | 39 | 2008 |
| Testicular receptor-4: novel regulator of glucocorticoid resistance D Zhang, L Du, AP Heaney The Journal of Clinical Endocrinology & Metabolism 101 (8), 3123-3133, 2016 | 38 | 2016 |
| Binding investigation of human 5-lipoxygenase with its inhibitors by SPR technology correlating with molecular docking simulation L Du, Z Zhang, X Luo, K Chen, X Shen, H Jiang Journal of biochemistry 139 (4), 715-723, 2006 | 37 | 2006 |
| Symmetrical 1‐pyrrolidineacetamide showing anti‐HIV activity through a new binding site on HIV‐1 integrase1 L Du, Y ZHAO, L YANG, Y ZHENG, Y Tang, X Shen, H JIANG Acta Pharmacologica Sinica 29 (10), 1261-1267, 2008 | 27 | 2008 |
| Targeting SUMOylation in cancer L Du, W Liu, ST Rosen Current opinion in oncology 33 (5), 520-525, 2021 | 22 | 2021 |
| SUMOylation inhibition enhances dexamethasone sensitivity in multiple myeloma L Du, W Liu, G Aldana-Masangkay, A Pozhitkov, F Pichiorri, Y Chen, ... Journal of Experimental & Clinical Cancer Research 41 (1), 8, 2022 | 20 | 2022 |
| Regulation of miR-34b/c-targeted gene expression program by SUMOylation YJ Li, L Du, G Aldana-Masangkay, X Wang, R Urak, SJ Forman, ... Nucleic acids research 46 (14), 7108-7123, 2018 | 20 | 2018 |
| Towards discovering dual functional inhibitors against both wild type and K103N mutant HIV-1 reverse transcriptases: molecular docking and QSAR studies on 4, 1-benzoxazepinone … Z Zhang, M Zheng, L Du, J Shen, X Luo, W Zhu, H Jiang Journal of computer-aided molecular design 20, 281-293, 2006 | 18 | 2006 |
| SUMOylation of E2F1 regulates expression of EZH2 L Du, MG Fakih, ST Rosen, Y Chen Cancer research 80 (19), 4212-4223, 2020 | 16 | 2020 |
| Helicobacter pylori acyl carrier protein: Expression, purification, and its interaction with β-hydroxyacyl-ACP dehydratase W Liu, L Du, L Zhang, J Chen, X Shen, H Jiang Protein expression and purification 52 (1), 74-81, 2007 | 15 | 2007 |
| SUMOylation inhibition enhances multiple myeloma sensitivity to lenalidomide L Du, W Liu, F Pichiorri, ST Rosen Cancer Gene Therapy 30 (4), 567-574, 2023 | 8 | 2023 |
| Mechanism of SUMOylation-mediated regulation of type I IFN expression L Du, W Liu, ST Rosen, Y Chen Journal of Molecular Biology 435 (5), 167968, 2023 | 8 | 2023 |
| 8-Cl-Ado and 8-NH2-Ado synergize with venetoclax to target the methionine-MAT2A-SAM axis in acute myeloid leukemia J Guo, R Buettner, L Du, Z Li, W Liu, R Su, Z Chen, Y Che, Y Zhang, R Ma, ... Leukemia, 1-10, 2024 | | 2024 |
