Cryptic peroxisomal targeting via alternative splicing and stop codon read-through in fungi J Freitag, J Ast, M Bölker Nature 485 (7399), 522-525, 2012 | 197 | 2012 |
Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals AC Stiebler, J Freitag, KO Schink, T Stehlik, BAM Tillmann, J Ast, M Bölker PLoS genetics 10 (10), e1004685, 2014 | 140 | 2014 |
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... Nature Communications 11 (1), 467, 2020 | 99 | 2020 |
Dual targeting of peroxisomal proteins J Ast, AC Stiebler, J Freitag, M Bölker Frontiers in physiology 4, 297, 2013 | 74 | 2013 |
Crosstalk between the Unfolded Protein Response and Pathways That Regulate Pathogenic Development in Ustilago maydis K Heimel, J Freitag, M Hampel, J Ast, M Bölker, J Kämper The Plant Cell 25 (10), 4262-4277, 2013 | 69 | 2013 |
GLP1R attenuates sympathetic response to high glucose via carotid body inhibition AG Pauza, P Thakkar, T Tasic, I Felippe, P Bishop, MP Greenwood, ... Circulation research 130 (5), 694-707, 2022 | 48 | 2022 |
Peroxisomes contribute to biosynthesis of extracellular glycolipids in fungi J Freitag, J Ast, U Linne, T Stehlik, D Martorana, M Bölker, B Sandrock Molecular microbiology 93 (1), 24-36, 2014 | 42 | 2014 |
Fungal peroxisomes as biosynthetic organelles T Stehlik, B Sandrock, J Ast, J Freitag Current opinion in microbiology 22, 8-14, 2014 | 35 | 2014 |
Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates P Poc, VA Gutzeit, J Ast, J Lee, BJ Jones, E D'Este, B Mathes, M Lehmann, ... Chemical Science 11 (30), 7871-7883, 2020 | 32 | 2020 |
Conditional and reversible activation of class A and BG protein-coupled receptors using tethered pharmacology T Podewin, J Ast, J Broichhagen, NHF Fine, D Nasteska, P Leippe, ... ACS Central Science 4 (2), 166-179, 2018 | 30 | 2018 |
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone T Podewin, J Broichhagen, C Frost, D Groneberg, J Ast, H Meyer-Berg, ... Chemical Science 8 (6), 4644-4653, 2017 | 25 | 2017 |
Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding A Adriaenssens, J Broichhagen, A De Bray, J Ast, A Hasib, B Jones, ... JCI insight 8 (10), 2023 | 24 | 2023 |
Reagents and models for detecting endogenous GLP1R and GIPR J Ast, J Broichhagen, DJ Hodson EBioMedicine 74, 2021 | 18 | 2021 |
14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells Y Mugabo, C Zhao, JJ Tan, A Ghosh, SA Campbell, E Fadzeyeva, F Paré, ... JCI insight 7 (8), 2022 | 17 | 2022 |
Sulfonated red and far-red rhodamines to visualize SNAP-and Halo-tagged cell surface proteins R Birke, J Ast, DA Roosen, J Lee, K Roßmann, C Huhn, B Mathes, ... Organic & Biomolecular Chemistry 20 (30), 5967-5980, 2022 | 17 | 2022 |
Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds L Walker, L Baumgartner, KC Keller, J Ast, S Trettner, NI Zur Nieden Toxicology Reports 2, 165-174, 2015 | 16 | 2015 |
Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling J Ast, D Nasteska, NHF Fine, DJ Nieves, Z Koszegi, Y Lanoiselée, ... Nature communications 14 (1), 301, 2023 | 12 | 2023 |
Expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo J Ast, AN Novak, T Podewin, NHF Fine, B Jones, A Tomas, R Birke, ... JACS Au 2 (4), 1007-1017, 2022 | 12 | 2022 |
SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells OE Olaniru, J Cheng, J Ast, A Arvaniti, P Atanes, GC Huang, AJF King, ... Molecular metabolism 53, 101285, 2021 | 9 | 2021 |
Two Pex5 proteins with different cargo specificity are critical for peroxisome function in Ustilago maydis J Ast, N Bäcker, E Bittner, D Martorana, H Ahmad, M Bölker, J Freitag Frontiers in Cell and Developmental Biology 10, 858084, 2022 | 6 | 2022 |