Peroxisomes are signaling platforms for antiviral innate immunity E Dixit, S Boulant, Y Zhang, ASY Lee, C Odendall, B Shum, N Hacohen, ... Cell 141 (4), 668-681, 2010 | 941 | 2010 |
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity JK Nuñez, ASY Lee, A Engelman, JA Doudna Nature 519 (7542), 193-198, 2015 | 435 | 2015 |
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression ASY Lee, PJ Kranzusch, JHD Cate Nature 522 (7554), 111-114, 2015 | 419 | 2015 |
Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity PJ Kranzusch, ASY Lee, JM Berger, JA Doudna Cell reports 3 (5), 1362-1368, 2013 | 386 | 2013 |
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation ASY Lee, PJ Kranzusch, JA Doudna, JHD Cate Nature 536 (7614), 96-99, 2016 | 348 | 2016 |
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus Bacterial artificial chromosome clone KF Brulois, H Chang, ASY Lee, A Ensser, LY Wong, Z Toth, SH Lee, ... Journal of Virology 86 (18), 9708-9720, 2012 | 331 | 2012 |
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals AT Whiteley, JB Eaglesham, CC de Oliveira Mann, BR Morehouse, ... Nature 567 (7747), 194-199, 2019 | 322 | 2019 |
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′, 3′ cGAMP Signaling PJ Kranzusch, SC Wilson, ASY Lee, JM Berger, JA Doudna, RE Vance Molecular cell 59 (6), 891-903, 2015 | 266 | 2015 |
Modular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation CC de Oliveira Mann, MH Orzalli, DS King, JC Kagan, ASY Lee, ... Cell reports 27 (4), 1165-1175. e5, 2019 | 179 | 2019 |
A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs ASY Lee, R Burdeinick-Kerr, SPJ Whelan Proceedings of the National Academy of Sciences 110 (1), 324-329, 2013 | 165 | 2013 |
Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis Z Ge, AB Rogers, Y Feng, A Lee, S Xu, NS Taylor, JG Fox Cellular microbiology 9 (8), 2070-2080, 2007 | 165 | 2007 |
CBASS immunity uses CARF-related effectors to sense 3′–5′-and 2′–5′-linked cyclic oligonucleotide signals and protect bacteria from phage infection B Lowey, AT Whiteley, AFA Keszei, BR Morehouse, IT Mathews, ... Cell 182 (1), 38-49. e17, 2020 | 163 | 2020 |
Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses SR Radoshitzky, JH Kuhn, CF Spiropoulou, CG Albariño, DP Nguyen, ... Proceedings of the National Academy of Sciences 105 (7), 2664-2669, 2008 | 147 | 2008 |
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity PJ Kranzusch, ASY Lee, SC Wilson, MS Solovykh, RE Vance, JM Berger, ... Cell 158 (5), 1011-1021, 2014 | 136 | 2014 |
cGAS-like receptors sense RNA and control 3′ 2′-cGAMP signaling in Drosophila KM Slavik, BR Morehouse, AE Ragucci, W Zhou, X Ai, Y Chen, L Li, Z Wei, ... Nature, 1-8, 2021 | 128 | 2021 |
A phosphorylation-regulated eIF3d translation switch mediates cellular adaptation to metabolic stress AM Lamper, RH Fleming, KM Ladd, ASY Lee Science 370 (6518), 853-856, 2020 | 79 | 2020 |
A Genome-Wide Small Interfering RNA Screen Identifies Host Factors Required for Vesicular Stomatitis Virus Infection ASY Lee, R Burdeinick-Kerr, SPJ Whelan Journal of virology 88 (15), 8355-8360, 2014 | 38 | 2014 |
Helicobacter hepaticus urease is not required for intestinal colonization but promotes hepatic inflammation in male A/JCr mice Z Ge, A Lee, MT Whary, AB Rogers, KJ Maurer, NS Taylor, DB Schauer, ... Microbial pathogenesis 45 (1), 18-24, 2008 | 28 | 2008 |
A molecular filter for the cnidarian stinging response K Weir, C Dupre, L van Giesen, ASY Lee, NW Bellono Elife 9, e57578, 2020 | 27 | 2020 |
Repression of ferritin light chain translation by human eIF3 MC Pulos-Holmes, DN Srole, MG Juarez, ASY Lee, DT McSwiggen, ... Elife 8, e48193, 2019 | 27 | 2019 |