A validated regulatory network for Th17 cell specification M Ciofani, A Madar, C Galan, ML Sellars, K Mace, F Pauli, A Agarwal, ... Cell 151 (2), 289-303, 2012 | 1284 | 2012 |
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ... Nature medicine 13 (10), 1203-1210, 2007 | 1044 | 2007 |
Notch promotes survival of pre–T cells at the β-selection checkpoint by regulating cellular metabolism M Ciofani, JC Zuniga-Pflücker Nature immunology 6 (9), 881-888, 2005 | 609 | 2005 |
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ... Nature 472 (7344), 486-490, 2011 | 599 | 2011 |
Maintenance of T cell specification and differentiation requires recurrent notch receptor–ligand interactions TM Schmitt, M Ciofani, HT Petrie, JC Zúñiga-Pflücker The Journal of experimental medicine 200 (4), 469-479, 2004 | 418 | 2004 |
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ... Science 338 (6109), 975-980, 2012 | 373 | 2012 |
Stage-specific and differential notch dependency at the αβ and γδ T lineage bifurcation M Ciofani, GC Knowles, DL Wiest, H von Boehmer, JC Zúñiga-Pflücker Immunity 25 (1), 105-116, 2006 | 329 | 2006 |
The thymus as an inductive site for T lymphopoiesis M Ciofani, JC Zúñiga-Pflücker Annu. Rev. Cell Dev. Biol. 23 (1), 463-493, 2007 | 325 | 2007 |
Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation M Ciofani, TM Schmitt, A Ciofani, AM Michie, N Cuburu, A Aublin, ... The Journal of Immunology 172 (9), 5230-5239, 2004 | 325 | 2004 |
Determining γδ versus αβ T cell development M Ciofani, JC Zúñiga-Pflücker Nature Reviews Immunology 10 (9), 657-663, 2010 | 214 | 2010 |
Marked induction of the helix-loop-helix protein Id3 promotes the γδ T cell fate and renders their functional maturation Notch independent JPH Lauritsen, GW Wong, SY Lee, JM Lefebvre, M Ciofani, M Rhodes, ... Immunity 31 (4), 565-575, 2009 | 190 | 2009 |
The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival M Mandal, C Borowski, T Palomero, AA Ferrando, P Oberdoerffer, F Meng, ... The Journal of experimental medicine 201 (4), 603-614, 2005 | 172 | 2005 |
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ... The Journal of experimental medicine 199 (3), 399-410, 2004 | 169 | 2004 |
JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation TM Carr, JD Wheaton, GM Houtz, M Ciofani Nature communications 8 (1), 301, 2017 | 119 | 2017 |
Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells ER Miraldi, M Pokrovskii, A Watters, DM Castro, N De Veaux, JA Hall, ... Genome research 29 (3), 449-463, 2019 | 113 | 2019 |
The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells MK Zuberbuehler, ME Parker, JD Wheaton, JR Espinosa, HR Salzler, ... Nature immunology 20 (1), 73-85, 2019 | 110 | 2019 |
Regulation of γδ T cell effector diversification in the thymus ME Parker, M Ciofani Frontiers in immunology 11, 42, 2020 | 104 | 2020 |
Dynamic microRNA gene transcription and processing during T cell development FF Kirigin, K Lindstedt, M Sellars, M Ciofani, SL Low, L Jones, F Bell, ... The Journal of Immunology 188 (7), 3257-3267, 2012 | 99 | 2012 |
Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents PR Juvvadi, D Fox III, BG Bobay, MJ Hoy, SMC Gobeil, RA Venters, ... Nature Communications 10 (1), 4275, 2019 | 97 | 2019 |
Transgenic mice for in vivo epigenome editing with CRISPR-based systems MP Gemberling, K Siklenka, E Rodriguez, KR Tonn-Eisinger, A Barrera, ... Nature methods 18 (8), 965-974, 2021 | 78 | 2021 |