关注
Zhijian Chen
Zhijian Chen
在 utsouthwestern.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
L Sun, J Wu, F Du, X Chen, ZJ Chen
Science 339 (6121), 786-791, 2013
41952013
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
RB Seth, L Sun, CK Ea, ZJ Chen
Cell 122 (5), 669-682, 2005
37762005
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
C Wang, L Deng, M Hong, GR Akkaraju, J Inoue, ZJ Chen
Nature 412 (6844), 346-351, 2001
26792001
Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
L Deng, C Wang, E Spencer, L Yang, A Braun, J You, C Slaughter, ...
Cell 103 (2), 351-361, 2000
24142000
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
J Wu, L Sun, X Chen, F Du, H Shi, C Chen, ZJ Chen
Science 339 (6121), 826-830, 2013
22412013
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
MU Gack, YC Shin, CH Joo, T Urano, C Liang, L Sun, O Takeuchi, S Akira, ...
Nature 446 (7138), 916-920, 2007
18512007
STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors
L Deng, H Liang, M Xu, X Yang, B Burnette, A Arina, XD Li, H Mauceri, ...
Immunity 41 (5), 843-852, 2014
17782014
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
Z Chen, J Hagler, VJ Palombella, F Melandri, D Scherer, D Ballard, ...
Genes & development 9 (13), 1586-1597, 1995
17611995
Ubiquitin signalling in the NF-κB pathway
ZJ Chen
Nature cell biology 7 (8), 758-765, 2005
16672005
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
Q Chen, L Sun, ZJ Chen
Nature immunology 17 (10), 1142-1149, 2016
16592016
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
S Liu, X Cai, J Wu, Q Cong, X Chen, T Li, F Du, J Ren, YT Wu, NV Grishin, ...
Science 347 (6227), aaa2630, 2015
15732015
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
YH Chiu, JB MacMillan, ZJ Chen
Cell 138 (3), 576-591, 2009
14162009
Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity
ZJ Chen, L Parent, T Maniatis
Cell 84 (6), 853-862, 1996
13181996
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
F Hou, L Sun, H Zheng, B Skaug, QX Jiang, ZJ Chen
Cell 146 (3), 448-461, 2011
13112011
Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
CK Ea, L Deng, ZP Xia, G Pineda, ZJ Chen
Molecular cell 22 (2), 245-257, 2006
12272006
Innate immune sensing and signaling of cytosolic nucleic acids
J Wu, ZJ Chen
Annual review of immunology 32, 461-488, 2014
12122014
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
Y Tanaka, ZJ Chen
Science signaling 5 (214), ra20-ra20, 2012
12082012
Nonproteolytic functions of ubiquitin in cell signaling
ZJ Chen, LJ Sun
Molecular cell 33 (3), 275-286, 2009
10902009
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
A Kanayama, RB Seth, L Sun, CK Ea, M Hong, A Shaito, YH Chiu, L Deng, ...
Molecular cell 15 (4), 535-548, 2004
10892004
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
XD Li, J Wu, D Gao, H Wang, L Sun, ZJ Chen
Science 341 (6152), 1390-1394, 2013
10732013
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