| Sarcoma treatment in the era of molecular medicine TGP Grünewald, M Alonso, S Avnet, A Banito, S Burdach, F Cidre‐Aranaz, ... EMBO molecular medicine 12 (11), e11131, 2020 | 196 | 2020 |
| Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets MC Baldauf, MF Orth, M Dallmayer, A Marchetto, JS Gerke, RA Rubio, ... Oncotarget 9 (2), 1587, 2018 | 86 | 2018 |
| Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes J Musa, F Cidre-Aranaz, MM Aynaud, MF Orth, MML Knott, O Mirabeau, ... Nature communications 10 (1), 4128, 2019 | 58 | 2019 |
| Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma A Marchetto, S Ohmura, MF Orth, MML Knott, MV Colombo, C Arrigoni, ... Nature communications 11 (1), 2423, 2020 | 42 | 2020 |
| Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies MML Knott, TLB Hölting, S Ohmura, T Kirchner, F Cidre-Aranaz, ... Cancer and Metastasis Reviews 38, 625-642, 2019 | 41 | 2019 |
| Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients G Sannino, A Marchetto, A Ranft, S Jabar, C Zacherl, R Alba-Rubio, ... EBioMedicine 47, 156-162, 2019 | 30 | 2019 |
| Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma S Ohmura, A Marchetto, MF Orth, J Li, S Jabar, A Ranft, E Vinca, ... Molecular Cancer 20, 1-7, 2021 | 29 | 2021 |
| Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma M Dallmayer, J Li, S Ohmura, R Alba Rubio, MC Baldauf, TLB Hölting, ... Cell death & disease 10 (2), 116, 2019 | 27 | 2019 |
| Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation MF Orth, D Surdez, T Faehling, AC Ehlers, A Marchetto, S Grossetête, ... Cell reports 41 (10), 2022 | 25 | 2022 |
| Detection of monoclonality in intestinal lymphoma with polymerase chain reaction for antigen receptor gene rearrangement analysis to differentiate from enteritis in dogs S Ohmura, M Leipig, I Schöpper, F Hergt, K Weber, BC Rütgen, ... Veterinary and comparative oncology 15 (1), 194-207, 2017 | 24 | 2017 |
| High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma MF Orth, TLB Hölting, M Dallmayer, FS Wehweck, T Paul, J Musa, ... Cancers 12 (3), 644, 2020 | 22 | 2020 |
| Systematic identification of cancer-specific MHC-binding peptides with RAVEN MC Baldauf, JS Gerke, A Kirschner, F Blaeschke, M Effenberger, ... Oncoimmunology 7 (9), e1481558, 2018 | 22 | 2018 |
| Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer J Li, S Ohmura, A Marchetto, MF Orth, R Imle, M Dallmayer, J Musa, ... Nature Communications 12 (1), 5356, 2021 | 13 | 2021 |
| Integrative clinical transcriptome analysis reveals TMPRSS2‐ERG dependency of prognostic biomarkers in prostate adenocarcinoma JS Gerke, MF Orth, Y Tolkach, L Romero‐Pérez, FS Wehweck, S Stein, ... International journal of cancer 146 (7), 2036-2046, 2020 | 13 | 2020 |
| Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma MF Orth, JS Gerke, T Knösel, A Altendorf‐Hofmann, J Musa, ... International journal of cancer 144 (4), 859-867, 2019 | 13 | 2019 |
| Tumor growth analysis of Ewing sarcoma cell lines using subcutaneous xenografts in mice F Cidre-Aranaz, S Ohmura Ewing Sarcoma: Methods and Protocols, 191-199, 2021 | 6 | 2021 |
| Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets. Oncotarget 9: 1587–1601 MC Baldauf, MF Orth, M Dallmayer, A Marchetto, JS Gerke, RA Rubio, ... | 6 | 2018 |
| Melting curve analysis in canine lymphoma by calculating maximum fluorescence decrease I Schöpper, S Ohmura, B Rütgen, H Tsujimoto, K Weber, J Hirschberger Veterinary and comparative oncology 15 (2), 563-575, 2017 | 5 | 2017 |
| Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma F Cidre-Aranaz, J Li, TLB Hölting, MF Orth, R Imle, S Kutschmann, ... Molecular Cancer 21, 1-7, 2022 | 3 | 2022 |
| Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma TLB Hölting, F Cidre-Aranaz, D Matzek, B Popper, SJ Jacobi, CM Funk, ... Molecular Cancer 21 (1), 199, 2022 | 2 | 2022 |
Thomas G. P. GrünewaldHopp-Children´s Cancer Center Heidelberg (KiTZ)在 kitz-heidelberg.de 的电子邮件经过验证
