Functional insights revealed by the kinetic mechanism of CRISPR/Cas9 AT Raper, AA Stephenson, Z Suo Journal of the American Chemical Society 140 (8), 2971-2984, 2018 | 148 | 2018 |
Bidirectional degradation of DNA cleavage products catalyzed by CRISPR/Cas9 AA Stephenson, AT Raper, Z Suo Journal of the American Chemical Society 140 (10), 3743-3750, 2018 | 73 | 2018 |
Sharpening the scissors: Mechanistic details of CRISPR/Cas9 improve functional understanding and inspire future research AT Raper, AA Stephenson, Z Suo Journal of the American Chemical Society 140 (36), 11142-11152, 2018 | 16 | 2018 |
Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma AA Stephenson, S Cao, DJ Taggart, VP Vyavahare, Z Suo European Journal of Medicinal Chemistry 213, 113135, 2021 | 14 | 2021 |
Gene editing and modulation for Duchenne muscular dystrophy AA Stephenson, KM Flanigan Progress in Molecular Biology and Translational Science 182, 225-255, 2021 | 13 | 2021 |
The inhibitor of κB kinase β (IKKβ) phosphorylates IκBα twice in a single binding event through a sequential mechanism AA Stephenson, DJ Taggart, G Xu, JD Fowler, H Wu, Z Suo Journal of Biological Chemistry 299 (1), 2023 | 8 | 2023 |
CRISPR-Cas9 homology-independent targeted integration of exons 1–19 restores full-length dystrophin in mice AA Stephenson, S Nicolau, TA Vetter, GP Dufresne, EC Frair, JE Sarff, ... Molecular Therapy-Methods & Clinical Development 30, 486-499, 2023 | 6 | 2023 |
Noncatalytic, N-terminal domains of DNA polymerase lambda affect its cellular localization and DNA damage response AA Stephenson, DJ Taggart, Z Suo Chemical research in toxicology 30 (5), 1240-1249, 2017 | 6 | 2017 |
Direct Incorporation of Exogenous Glycerol Leads to Increased Triacylglycerol Formation in Chlorella vulgaris AL Smythers, EG Napier, EL Higginbotham, AT Holland, AA Stephenson, ... Energy & fuels 33 (11), 11125-11134, 2019 | 4 | 2019 |
Conformational transitions of Streptococcus pyogenes Cas9 induced by salt and single-guide RNA binding Y He, N Zalenski, AA Stephenson, AT Raper, C Ghimire, Z Suo Journal of Biological Chemistry, 108120, 2024 | | 2024 |
435P Correction of a common Duchenne muscular dystrophy mutation by CRISPR/Cas9 gene editing using homology-independent targeted integration S Nicolau, J Sarff, T Vetter, A Stephenson, K Flanigan Neuromuscular Disorders 43, 104441.306, 2024 | | 2024 |
Products and methods for treatment of dystrophin-based myopathies using crispr-cas9 to correct dmd exon duplications K Flanigan, AA Stephenson US Patent App. 18/279,169, 2024 | | 2024 |
Aav-mediated homology-independent targeted integration gene editing for correction of diverse dmd mutations in patients with muscular dystrophy K Flanigan, AA Stephenson, J Havens US Patent App. 18/245,025, 2023 | | 2023 |
Aav-mediated homology-independent targeted integration gene editing for correction of diverse dmd mutations in patients with muscular dystrophy K FLANIGAN, AA STEPHENSON, J HAVENS | | 2023 |
Correction of DMD Proximal Hotspot Mutations Using Homology-Independent Targeted Integration AA Stephenson, S Nicolau, T Vetter, K Flanigan MOLECULAR THERAPY 30 (4), 273-273, 2022 | | 2022 |
Aav-mediated homology-independent targeted integration gene editing for correction of diverse dmd mutations in patients with muscular dystrophy K FLANIGAN, AA Stephenson, J HAVENS | | 2022 |
Homology-Independent Targeted Integration for Correction of DMD Distal Hotspot Mutations AA Stephenson, JR Havens, S Nicolau, T Vetter, KM Flanigan MOLECULAR THERAPY 29 (4), 190-190, 2021 | | 2021 |
CRISPR/Cas9 Correction of Single and Multi-Exon Duplications in Duchenne Muscular Dystrophy S Nicolau, AA Stephenson, TA Vetter, J Havens, LV Gushchina, ... MOLECULAR THERAPY 29 (4), 198-198, 2021 | | 2021 |
Gene Editing with CRISPR/Cas9 to Correct DMD Exon Duplication Mutations in Patient-Derived Cells and Mice AA Stephenson, JR Havens, KM Flanigan MOLECULAR THERAPY 28 (4), 104-104, 2020 | | 2020 |
Enhancement of Algal Biofeedstocks in a Mixotrophic Batch Culture Supplemented with Exogenous Glycerol AL Smythers, E Higginbotham, A Holland, A Stephenson, DRJ Kolling The FASEB Journal 33 (S1), 653.2-653.2, 2019 | | 2019 |