BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 946 | 2015 |
Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch N Liu, VV Hargreaves, Q Zhu, JV Kurland, J Hong, W Kim, F Sher, ... Cell 173 (2), 430-442. e17, 2018 | 422 | 2018 |
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ... Science 351 (6270), 285-289, 2016 | 350 | 2016 |
Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2 F Sher, R Rößler, N Brouwer, V Balasubramaniyan, E Boddeke, S Copray Stem cells 26 (11), 2875-2883, 2008 | 216 | 2008 |
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis F Sher, M Hossain, D Seruggia, VAC Schoonenberg, Q Yao, P Cifani, ... Nature genetics 51 (7), 1149-1159, 2019 | 97 | 2019 |
Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging S Copray, JL Huynh, F Sher, P Casaccia‐Bonnefil, E Boddeke Glia 57 (15), 1579-1587, 2009 | 88 | 2009 |
Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes F Sher, E Boddeke, M Olah, S Copray PloS one 7 (7), e40399, 2012 | 81 | 2012 |
An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility S Lessard, ES Gatof, M Beaudoin, PG Schupp, F Sher, A Ali, S Prehar, ... The Journal of clinical investigation 127 (8), 3065-3074, 2017 | 68 | 2017 |
Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells F Sher, E Boddeke, S Copray Cellular Reprogramming (Formerly" Cloning and Stem Cells") 13 (1), 1-6, 2011 | 67 | 2011 |
Oligodendrocyte differentiation and implantation: new insights for remyelinating cell therapy F Sher, V Balasubramaniyan, E Boddeke, S Copray Current opinion in neurology 21 (5), 607-614, 2008 | 60 | 2008 |
Strict in vivo specificity of the Bcl11a erythroid enhancer EC Smith, S Luc, DM Croney, MB Woodworth, LC Greig, Y Fujiwara, ... Blood, The Journal of the American Society of Hematology 128 (19), 2338-2342, 2016 | 49 | 2016 |
Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model F Sher, G van Dam, E Boddeke, S Copray Stem Cells 27 (7), 1582-1591, 2009 | 46 | 2009 |
Intraventricularly injected Olig2-NSCs attenuate established relapsing–remitting EAE in mice F Sher, S Amor, W Gerritsen, D Baker, SL Jackson, E Boddeke, S Copray Cell transplantation 21 (9), 1883-1897, 2012 | 41 | 2012 |
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ... Nature methods 15 (12), 992-993, 2018 | 37 | 2018 |
CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis VAC Schoonenberg, MA Cole, Q Yao, C Macias-Treviño, F Sher, ... Genome biology 19, 1-19, 2018 | 33 | 2018 |
Crispr-Cas9 saturating mutagenesis reveals an Achilles heel in the BCL11A erythroid enhancer for fetal hemoglobin induction (by genome editing) DE Bauer, MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, ... Blood 126 (23), 638, 2015 | 7 | 2015 |
Rö ssler F Sher R., Brouwer, N., Balasubramaniyan, V., Boddeke, E., and Copray, S, 2875-2883, 2008 | 6 | 2008 |
Fetal hemoglobin (HbF) silencer BCL11A acts through a novel DNA-motif in the gamma-globin promoters, simplifying the model for hemoglobin switching N Liu, VV Hargreaves, J Hong, W Kim, J Kurland, Q Zhu, F Sher, ... Blood 130, 283, 2017 | 3 | 2017 |
An Essential Erythroid-Specific Enhancer of ATP2B4 Associated with Red Blood Cell Traits and Malaria Susceptibility EN Stern, S Lessard, PG Schupp, F Sher, G Lettre, DE Bauer Blood, The Journal of the American Society of Hematology 128 (22), 1250-1250, 2016 | 2 | 2016 |
Rational Targeting of a NuRD Sub-Complex for Fetal Hemoglobin Induction Following Comprehensive in Situ Mutagenesis M Hossain, F Sher, D Seruggia, V Schoonenberg, MA Cole, P Cifani, ... Blood 132, 2342, 2018 | 1 | 2018 |