| Activity-dependent spatially localized miRNA maturation in neuronal dendrites S Sambandan, G Akbalik, L Kochen, J Rinne, J Kahlstatt, C Glock, ... Science 355 (6325), 634-637, 2017 | 206 | 2017 |
| Cell-type-specific metabolic labeling of nascent proteomes in vivo B Alvarez-Castelao, CT Schanzenbächer, C Hanus, C Glock, S tom Dieck, ... Nature biotechnology 35 (12), 1196-1201, 2017 | 173 | 2017 |
| Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain M Díaz‐Hernández, AG Valera, MA Morán, P Gómez‐Ramos, ... Journal of neurochemistry 98 (5), 1585-1596, 2006 | 126 | 2006 |
| The regulation of synaptic protein turnover B Alvarez-Castelao, EM Schuman Journal of Biological Chemistry 290 (48), 28623-28630, 2015 | 125 | 2015 |
| Unconventional secretory processing diversifies neuronal ion channel properties C Hanus, H Geptin, G Tushev, S Garg, B Alvarez-Castelao, S Sambandan, ... elife 5, e20609, 2016 | 103 | 2016 |
| Constitutive/hypoxic degradation of HIF-α proteins by the proteasome is independent of von Hippel Lindau protein ubiquitylation and the transactivation activity of the protein X Kong, B Alvarez-Castelao, Z Lin, JG Castano, J Caro Journal of Biological Chemistry 282 (21), 15498-15505, 2007 | 99 | 2007 |
| Proteome dynamics during homeostatic scaling in cultured neurons AR Dörrbaum, B Alvarez-Castelao, B Nassim-Assir, JD Langer, ... Elife 9, e52939, 2020 | 85 | 2020 |
| Mechanism of direct degradation of IκBα by 20S proteasome B Alvarez-Castelao, JG Castaño FEBS letters 579 (21), 4797-4802, 2005 | 80 | 2005 |
| The integrated stress response contributes to tRNA synthetase–associated peripheral neuropathy EL Spaulding, TJ Hines, P Bais, ALD Tadenev, R Schneider, D Jewett, ... Science 373 (6559), 1156-1161, 2021 | 78 | 2021 |
| Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines B Alvarez-Castelao, M Goethals, J Vandekerckhove, JG Castaño Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (2), 352-365, 2014 | 62 | 2014 |
| Cell-type-specific metabolic labeling, detection and identification of nascent proteomes in vivo B Alvarez-Castelao, CT Schanzenbächer, JD Langer, EM Schuman Nature protocols 14 (2), 556-575, 2019 | 60 | 2019 |
| α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines B Martìn-Clemente, B Alvarez-Castelao, I Mayo, AB Sierra, V Dìaz, ... Journal of Biological Chemistry 279 (51), 52984-52990, 2004 | 60 | 2004 |
| Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons JD Perez, ST Dieck, B Alvarez-Castelao, G Tushev, ICW Chan, ... Elife 10, e63092, 2021 | 53 | 2021 |
| Synphilin-1 inhibits alpha-synuclein degradation by the proteasome B Alvarez-Castelao, JG Castaño Cellular and Molecular Life Sciences 68, 2643-2654, 2011 | 44 | 2011 |
| Proteostatic regulation in neuronal compartments SL Giandomenico, B Alvarez-Castelao, EM Schuman Trends in Neurosciences 45 (1), 41-52, 2022 | 41 | 2022 |
| The switch-like expression of heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition B Alvarez-Castelao, S tom Dieck, CM Fusco, P Donlin-Asp, JD Perez, ... Elife 9, e52714, 2020 | 40 | 2020 |
| A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis B Alvarez-Castelao, C Ruiz-Rivas, JG Castaño Biochemistry research international 2012 (1), 823597, 2012 | 39 | 2012 |
| Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome B Alvarez-Castelao, C Muñoz, I Sánchez, M Goethals, J Vandekerckhove, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (2), 524-533, 2012 | 33 | 2012 |
| P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies C Di Lauro, C Bianchi, Á Sebastián-Serrano, L Soria-Tobar, ... Progress in Neurobiology 208, 102173, 2022 | 24 | 2022 |
| The N-terminal region of Nurr1 (aa 1–31) is essential for its efficient degradation by the ubiquitin proteasome pathway B Alvarez-Castelao, F Losada, P Ahicart, JG Castano PLoS One 8 (2), e55999, 2013 | 20 | 2013 |
