High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli H Nozach, C Fruchart-Gaillard, F Fenaille, F Beau, OHP Ramos, B Douzi, ... Microbial cell factories 12, 1-16, 2013 | 77 | 2013 |
Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using 89Zr … VL Tran, A Novell, N Tournier, M Gerstenmayer, A Schweitzer-Chaput, ... Journal of Controlled Release 328, 304-312, 2020 | 44 | 2020 |
Fab is the most efficient format to express functional antibodies by yeast surface display C Sivelle, R Sierocki, K Ferreira-Pinto, S Simon, B Maillere, H Nozach MAbs 10 (5), 720-729, 2018 | 31 | 2018 |
Synthesis and in vitro and in vivo evaluation of MMP-12 selective optical probes T Bordenave, M Helle, F Beau, D Georgiadis, L Tepshi, M Bernes, Y Ye, ... Bioconjugate chemistry 27 (10), 2407-2417, 2016 | 31 | 2016 |
The 3D model of the lipase/acyltransferase from Candida parapsilosis, a tool for the elucidation of structural determinants in CAL-A lipase superfamily M Subileau, AH Jan, H Nozac'h, M Pérez-Gordo, V Perrier, E Dubreucq Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (10), 1400-1411, 2015 | 28 | 2015 |
High Therapeutic Efficacy of a New Survivin LSP-Cancer Vaccine Containing CD4+ and CD8+ T-Cell Epitopes F Onodi, C Maherzi-Mechalikh, A Mougel, N Ben Hamouda, C Taboas, ... Frontiers in Oncology 8, 517, 2018 | 23 | 2018 |
High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coli NJ Saez, H Nozach, M Blemont, R Vincentelli JoVE (Journal of Visualized Experiments), e51464, 2014 | 22 | 2014 |
The tumor antigen cyclin B1 hosts multiple CD4 T cell epitopes differently recognized by pre-existing naive and memory cells in both healthy and cancer donors C Chevaleyre, N Benhamouda, E Favry, E Fabre, A Mhoumadi, H Nozach, ... The Journal of Immunology 195 (4), 1891-1901, 2015 | 20 | 2015 |
Optimizing Immuno-PET imaging of tumor PD-L1 expression: pharmacokinetic, Biodistribution, and Dosimetric comparisons of 89Zr-labeled anti-PD-L1 antibody formats A Bouleau, H Nozach, S Dubois, D Kereselidze, C Chevaleyre, CI Wang, ... Journal of Nuclear Medicine 63 (8), 1259-1265, 2022 | 19 | 2022 |
Grafting of functional motifs onto protein scaffolds identified by PDB screening–an efficient route to design optimizable protein binders R Tlatli, H Nozach, G Collet, F Beau, L Vera, E Stura, V Dive, P Cuniasse The FEBS Journal 280 (1), 139-159, 2013 | 18 | 2013 |
An antibody targeting type III secretion system induces broad protection against Salmonella and Shigella infections R Sierocki, B Jneid, ML Orsini Delgado, M Plaisance, B Maillère, ... PLoS neglected tropical diseases 15 (3), e0009231, 2021 | 9 | 2021 |
Pegylation reduces the uptake of certolizumab pegol by dendritic cells and epitope presentation to T-cells M de Bourayne, S Meunier, S Bitoun, E Correia, X Mariette, H Nozach, ... Frontiers in Immunology 13, 808606, 2022 | 8 | 2022 |
Deep mutational engineering of broadly-neutralizing nanobodies accommodating SARS-CoV-1 and 2 antigenic drift A Laroche, ML Orsini Delgado, B Chalopin, P Cuniasse, S Dubois, ... MAbs 14 (1), 2076775, 2022 | 7 | 2022 |
Monitoring In Vivo Performances of Protein–Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging H Cahuzac, A Sallustrau, C Malgorn, F Beau, P Barbe, V Babin, S Dubois, ... Journal of medicinal chemistry 65 (9), 6953-6968, 2022 | 6 | 2022 |
Impact of radiolabeling strategies on the pharmacokinetics and distribution of an anti-PD-L1 PET ligand VL Tran, A Bouleau, H Nozach, M Richard, C Chevaleyre, S Dubois, ... Molecular Pharmaceutics 19 (10), 3673-3680, 2022 | 5 | 2022 |
Efficient PD-L1 imaging of murine glioblastoma with FUS-aided immunoPET by leveraging FcRn-antibody interaction C Chevaleyre, A Novell, N Tournier, A Dauba, S Dubois, D Kereselidze, ... Theranostics 13 (15), 5584, 2023 | 4 | 2023 |
Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels CF Gaillard, ABD Ouadda, L Ciccone, E Girard, S Mikaeeli, A Evagelidis, ... Molecular metabolism 67, 101662, 2023 | 4 | 2023 |
Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold T Pruvost, M Mathieu, S Dubois, B Maillère, E Vigne, H Nozach MAbs 15 (1), 2175311, 2023 | 3 | 2023 |
Fluorine-18 and Radiometal Labeling of Biomolecules via Disulfide Rebridging M Richard, S Martin Aubert, C Denis, S Dubois, H Nozach, C Truillet, ... Bioconjugate Chemistry 34 (11), 2123-2132, 2023 | 2 | 2023 |
Broad Sarbecovirus Neutralization by Combined Memory B-cell Antibodies to Ancestral SARS-CoV-2 C Planchais, I Fernández, B Chalopin, T Bruel, P Rosenbaum, M Beretta, ... iScience, 2024 | | 2024 |