Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer R Troisi, V Napolitano, V Spiridonova, I Russo Krauss, F Sica Nucleic acids research 46 (22), 12177-12185, 2018 | 62 | 2018 |
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers IR Krauss, V Napolitano, L Petraccone, R Troisi, V Spiridonova, CA Mattia, ... International journal of biological macromolecules 107, 1697-1705, 2018 | 41 | 2018 |
Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands R Troisi, N Balasco, I Autiero, L Vitagliano, F Sica International journal of molecular sciences 22 (19), 10803, 2021 | 32 | 2021 |
Antimicrobial Applications of Green Synthesized Bimetallic Nanoparticles from Ocimum basilicum PR More, C Zannella, V Folliero, F Foglia, R Troisi, A Vergara, G Franci, ... Pharmaceutics 14 (11), 2457, 2022 | 17 | 2022 |
Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12 I Smirnov, N Kolganova, R Troisi, F Sica, E Timofeev Molecular Therapy-Nucleic Acids 23, 863-871, 2021 | 17 | 2021 |
Structure–Activity Relationship Study of a Potent α‐Thrombin Binding Aptamer Incorporating Hexitol Nucleotides M De Fenza, E Eremeeva, R Troisi, H Yang, A Esposito, F Sica, ... Chemistry–A European Journal 26 (43), 9589-9597, 2020 | 17 | 2020 |
Molecular dynamics simulations of human α-thrombin in different structural contexts: Evidence for an aptamer-guided cooperation between the two exosites R Troisi, N Balasco, L Vitagliano, F Sica Journal of Biomolecular Structure and Dynamics 39 (6), 2199-2209, 2021 | 14 | 2021 |
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin R Troisi, N Balasco, A Santamaria, L Vitagliano, F Sica International Journal of Biological Macromolecules 181, 858-867, 2021 | 11 | 2021 |
Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide R Troisi, V Napolitano, E Rossitto, W Osman, M Nagano, K Wakui, ... Nucleic Acids Research 51 (16), 8880-8890, 2023 | 7 | 2023 |
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers R Troisi, C Riccardi, KP de Carvasal, M Smietana, F Morvan, ... Molecular Therapy-Nucleic Acids 30, 585-594, 2022 | 7 | 2022 |
Aptamers: Functional-Structural Studies and Biomedical Applications R Troisi, F Sica International Journal of Molecular Sciences 23 (9), 4796, 2022 | 7 | 2022 |
New insight into the traditional model of the coagulation cascade and its regulation: illustrated review of a three-dimensional view R Troisi, N Balasco, I Autiero, F Sica, L Vitagliano Research and Practice in Thrombosis and Haemostasis, 102160, 2023 | 6 | 2023 |
Structural Insights into Protein–Aptamer Recognitions Emerged from Experimental and Computational Studies R Troisi, N Balasco, I Autiero, L Vitagliano, F Sica International Journal of Molecular Sciences 24 (22), 16318, 2023 | 5 | 2023 |
Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases R Culurciello, A Bosso, R Troisi, V Barrella, I Di Nardo, M Borriello, ... International Journal of Molecular Sciences 23 (15), 8781, 2022 | 5 | 2022 |
The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima G Smaldone, A Ruggiero, N Balasco, A Abuhammad, I Autiero, D Caruso, ... Acta Crystallographica Section F: Structural Biology Communications 75 (11 …, 2019 | 5 | 2019 |
Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry G Tito, R Troisi, G Ferraro, A Geri, L Massai, L Messori, F Sica, A Merlino Dalton Transactions 52 (21), 6992-6996, 2023 | 4 | 2023 |
The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition F Sica, IR Krauss, R Troisi, A Bosso, R Culurciello, C Carluccio, M Trapani, ... International Journal of Biological Macromolecules 182, 659-668, 2021 | 3 | 2021 |
Tailoring the stress response of human skin cells by substantially limiting the nuclear localization of angiogenin R Culurciello, I Di Nardo, A Bosso, F Tortora, R Troisi, F Sica, A Arciello, ... Heliyon 10 (3), 2024 | 2 | 2024 |
Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study R Troisi, F Galardo, G Ferraro, F Sica, A Merlino Inorganic Chemistry 62 (2), 675-678, 2023 | 2 | 2023 |
Structural overview of DNA and RNA G-quadruplexes in their interaction with proteins R Troisi, F Sica Current Opinion in Structural Biology 87, 102846, 2024 | | 2024 |