How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models MW Van Gisbergen, AM Voets, MHW Starmans, IFM de Coo, R Yadak, ... Mutation Research/Reviews in Mutation Research 764, 16-30, 2015 | 217 | 2015 |
Decision support systems for personalized and participative radiation oncology P Lambin, J Zindler, BGL Vanneste, L Van De Voorde, D Eekers, ... Advanced drug delivery reviews 109, 131-153, 2017 | 162 | 2017 |
New ways to image and target tumour hypoxia and its molecular responses LJ Dubois, R Niemans, SJA van Kuijk, KM Panth, NK Parvathaneni, ... Radiotherapy and Oncology 116 (3), 352-357, 2015 | 62 | 2015 |
HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells E Moreno Roig, AJ Groot, A Yaromina, TC Hendrickx, LMO Barbeau, ... Cells 8 (1), 45, 2019 | 53 | 2019 |
Mitochondrial neurogastrointestinal encephalomyopathy caused by thymidine phosphorylase enzyme deficiency: from pathogenesis to emerging therapeutic options R Yadak, P Sillevis Smitt, MW van Gisbergen, NP van Til, IFM de Coo Frontiers in cellular neuroscience 11, 31, 2017 | 53 | 2017 |
Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer TWH Meijer, WJM Peeters, LJ Dubois, MW van Gisbergen, R Biemans, ... Lung Cancer 126, 32-40, 2018 | 47 | 2018 |
Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans EBM Nascimento, LM Sparks, A Divoux, MW van Gisbergen, ... Obesity 26 (1), 135-140, 2018 | 35 | 2018 |
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs BF Côrte-Real, I Hamad, RA Hornero, S Geisberger, J Roels, ... Cell Metabolism 35 (2), 299-315. e8, 2023 | 28 | 2023 |
Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets MW van Gisbergen, K Offermans, AM Voets, NG Lieuwes, R Biemans, ... Frontiers in Oncology 10, 770, 2020 | 26 | 2020 |
New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs SJA van Kuijk, NK Parvathaneni, R Niemans, MW van Gisbergen, F Carta, ... European journal of medicinal chemistry 127, 691-702, 2017 | 26 | 2017 |
Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells MW van Gisbergen, M Cebula, J Zhang, A Ottosson-Wadlund, L Dubois, ... Molecular pharmaceutics 13 (6), 2010-25, 2016 | 26 | 2016 |
Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells D Grasso, HCD Medeiros, LX Zampieri, V Bol, P Danhier, ... Frontiers in Pharmacology 11, 263, 2020 | 24 | 2020 |
ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer TG Keulers, A Koch, MW van Gisbergen, LMO Barbeau, MI Zonneveld, ... Autophagy 18 (8), 1898-1914, 2022 | 22 | 2022 |
An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoHER and quercetin H Jacobs, M Moalin, MW van Gisbergen, A Bast, WJF van der Vijgh, ... Free Radical Biology and Medicine 51 (11), 2118-2123, 2011 | 22 | 2011 |
Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress MW van Gisbergen, AM Voets, R Biemans, RF Hoffmann, ... PloS one 12 (8), e0182508, 2017 | 19 | 2017 |
Metabolic rewiring in radiation oncology toward improving the therapeutic ratio MW Van Gisbergen, E Zwilling, LJ Dubois Frontiers in Oncology 11, 653621, 2021 | 15 | 2021 |
Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy F Van Tienen, R Zelissen, E Timmer, M Van Gisbergen, P Lindsey, ... Stem cell research & therapy 10, 1-10, 2019 | 15 | 2019 |
Nitroglycerin as a radiosensitizer in non-small cell lung cancer: Results of a prospective imaging-based phase II trial BJT Reymen, MW van Gisbergen, AJG Even, CML Zegers, M Das, E Vegt, ... Clinical and Translational Radiation Oncology 21, 49-55, 2020 | 13 | 2020 |
Cachexia, Sarcopenia and Muscle Wasting, Maastricht, The Netherlands, 7–9 December 2018 RPG Hayhoe, MAH Lentjes, AA Mulligan, RN Luben, KT Khaw, AA Welch Journal of Cachexia, Sarcopenia and Muscle 9, 1121-1184, 2018 | 3 | 2018 |
SP-0597: Nitroglycerin as a sensitizer in the treatment of non small cell lung cancer: from cells in vitro to phase 3 trial B Reyman, M Van Gisbergen, K Zegers, L Dubois, P Lambin Radiotherapy and Oncology 115, S290-S291, 2015 | 2 | 2015 |