Riluzole: A neuroprotective drug with potential as a novel anti‑cancer agent A Blyufer, S Lhamo, C Tam, I Tariq, T Thavornwatanayong, SS Mahajan International journal of oncology 59 (5), 1-11, 2021 | 45 | 2021 |
Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B TS Mehlman, JT Biel, SM Azeem, ER Nelson, S Hossain, L Dunnett, ... Elife 12, e84632, 2023 | 36 | 2023 |
AI is a viable alternative to high throughput screening: a 318-target study Scientific reports 14 (1), 7526, 2024 | 21 | 2024 |
Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase M Raghubir, SM Azeem, R Hasnat, CN Rahman, L Wong, S Yan, ... Scientific reports 11 (1), 20974, 2021 | 12 | 2021 |
Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors SM Azeem, AN Muwonge, N Thakkar, KW Lam, KM Frey Journal of Molecular Graphics and Modelling 79, 133-139, 2018 | 5 | 2018 |
Application of Structure-based Methods to Analyze Resistance Mutations for Chemically Diverse Non-Nucleoside Reverse Transcriptase Inhibitors T Tabassum, SM Azeem, AN Muwonge, KM Frey Current HIV Research 18 (4), 283-291, 2020 | 1 | 2020 |
Perturbing Protein and Ligand Conformational Landscapes to Link Dynamics and Function in Protein Tyrosine Phosphatases T Mehlman, L Margent, A Ebrahim, V Woods, N Singh, B Riley, SM Azeem, ... PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Hydrogen-Deuterium Exchange (HDX) and X-ray Crystallography Reveal Novel Mechanisms of Allosteric Modulation in PTP1B V Woods, T Mehlman, S Azeem, S Hossain, N Singh, D Keedy PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Remote control of a dynamic enzyme by leveraging small-molecule fragments T Skaist, S Azeem, D Keedy ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Predicting Resistance To Investigational Microbicide MIV‐150 Using Structure‐based methods and Fluorescence Enzyme Inhibition AN Muwonge, SM Azeem, KM Frey The FASEB Journal 32, 830.1-830.1, 2018 | | 2018 |
Exploiting the Components Leading to Mutational Resistance in Rigid and Flexible Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) SM Azeem, AN Muwonge, M Ivatarov, M Yunayev, KM Frey FASEB JOURNAL 32 (1), 2018 | | 2018 |