Obesity-associated variants within FTO form long-range functional connections with IRX3 S Smemo, JJ Tena, KH Kim, ER Gamazon, NJ Sakabe, C Gómez-Marín, ... Nature 507 (7492), 371-375, 2014 | 1446 | 2014 |
A pliable mediator acts as a functional rather than an architectural bridge between promoters and enhancers L El Khattabi, H Zhao, J Kalchschmidt, N Young, S Jung, P Van Blerkom, ... Cell 178 (5), 1145-1158. e20, 2019 | 216 | 2019 |
DNA methylation in lung cells is associated with asthma endotypes and genetic risk J Nicodemus-Johnson, RA Myers, NJ Sakabe, DR Sobreira, DK Hogarth, ... JCI insight 1 (20), 2016 | 169 | 2016 |
A promoter interaction map for cardiovascular disease genetics LE Montefiori, DR Sobreira, NJ Sakabe, I Aneas, AC Joslin, GT Hansen, ... Elife 7, e35788, 2018 | 142 | 2018 |
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5 DR Sobreira, AC Joslin, Q Zhang, I Williamson, GT Hansen, KM Farris, ... Science 372 (6546), 1085-1091, 2021 | 88 | 2021 |
Time course and side‐by‐side analysis of mesodermal, pre‐myogenic, myogenic and differentiated cell markers in the chicken model for skeletal muscle formation F Berti, JM Nogueira, S Wöhrle, DR Sobreira, K Hawrot, S Dietrich Journal of anatomy 227 (3), 361-382, 2015 | 61 | 2015 |
Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development CJ Boogerd, X Zhu, I Aneas, N Sakabe, L Zhang, DR Sobreira, ... Circulation research 123 (4), 428-442, 2018 | 53 | 2018 |
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region I Aneas, DC Decker, CL Howard, DR Sobreira, NJ Sakabe, KM Blaine, ... Nature Communications 12 (1), 6115, 2021 | 43 | 2021 |
Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth NJ Sakabe, I Aneas, N Knoblauch, DR Sobreira, N Clark, C Paz, C Horth, ... Science advances 6 (49), eabc8696, 2020 | 37 | 2020 |
Evolutionarily conserved morphogenetic movements at the vertebrate head–trunk interface coordinate the transport and assembly of hypopharyngeal structures C Lours-Calet, LE Alvares, AS El-Hanfy, S Gandesha, EH Walters, ... Developmental biology 390 (2), 231-246, 2014 | 34 | 2014 |
Genome‐wide association and multi‐omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women J Chung, A Das, X Sun, DR Sobreira, YY Leung, C Igartua, S Mozaffari, ... Alzheimer's & Dementia 19 (3), 896-908, 2023 | 33 | 2023 |
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci AC Joslin, DR Sobreira, GT Hansen, NJ Sakabe, I Aneas, LE Montefiori, ... Nature communications 12 (1), 5253, 2021 | 32 | 2021 |
Dactgenes are chordate specific regulators at the intersection of Wnt and Tgf-β signaling pathways FR Schubert, DR Sobreira, RG Janousek, LE Alvares, S Dietrich BMC Evolutionary Biology 14, 1-20, 2014 | 24 | 2014 |
Genetics of sexually dimorphic adipose distribution in humans GT Hansen, DR Sobreira, ZT Weber, AG Thornburg, I Aneas, L Zhang, ... Nature Genetics 55 (3), 461-470, 2023 | 23 | 2023 |
Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF‐β signaling pathways during chicken limb development LA Sensiate, DR Sobreira, FC Da Veiga, DJ Peterlini, AV Pedrosa, ... Developmental Dynamics 243 (3), 428-439, 2014 | 23 | 2014 |
Elastic fiber assembly in the adult mouse pubic symphysis during pregnancy and postpartum SR Consonni, CC Werneck, DR Sobreira, F Kühne, SG Moraes, ... Biology of reproduction 86 (5), 151, 1-10, 2012 | 21 | 2012 |
Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma BA Helling, DR Sobreira, GT Hansen, NJ Sakabe, K Luo, C Billstrand, ... Communications Biology 3 (1), 678, 2020 | 15 | 2020 |
Chicken dapper genes are versatile markers for mesodermal tissues, embryonic muscle stem cells, neural crest cells, and neurogenic placodes LE Alvares, FL Winterbottom, D Rodrigues Sobreira, J Xavier‐Neto, ... Developmental dynamics: an official publication of the American Association …, 2009 | 13 | 2009 |
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes V Glunk, S Laber, N Sinnott-Armstrong, DR Sobreira, SM Strobel, ... Nature Metabolism 5 (5), 861-879, 2023 | 11 | 2023 |
A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans OA Gray, J Yoo, DR Sobreira, J Jousma, D Witonsky, NJ Sakabe, YJ Peng, ... Science Advances 8 (47), eade1942, 2022 | 10 | 2022 |