Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages M Kratz, BR Coats, KB Hisert, D Hagman, V Mutskov, E Peris, ... Cell metabolism 20 (4), 614-625, 2014 | 789 | 2014 |
Metabolically activated adipose tissue macrophages perform detrimental and beneficial functions during diet-induced obesity BR Coats, KQ Schoenfelt, VC Barbosa-Lorenzi, E Peris, C Cui, A Hoffman, ... Cell reports 20 (13), 3149-3161, 2017 | 270 | 2017 |
Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea I Almendros, Y Wang, L Becker, FE Lennon, J Zheng, BR Coats, ... American journal of respiratory and critical care medicine 189 (5), 593-601, 2014 | 192 | 2014 |
Augmented protein kinase C-α–induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure RJ Belin, MP Sumandea, EJ Allen, K Schoenfelt, H Wang, RJ Solaro, ... Circulation research 101 (2), 195-204, 2007 | 187 | 2007 |
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis C Cui, K Chakraborty, XA Tang, G Zhou, KQ Schoenfelt, KM Becker, ... Cell 184 (12), 3163-3177. e21, 2021 | 167 | 2021 |
Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer P Tiwari, A Blank, C Cui, KQ Schoenfelt, G Zhou, Y Xu, G Khramtsova, ... Journal of Experimental Medicine 216 (6), 1345-1358, 2019 | 101 | 2019 |
Myosin head orientation: a structural determinant for the Frank-Starling relationship GP Farman, D Gore, E Allen, K Schoenfelt, TC Irving, PP de Tombe American Journal of Physiology-Heart and Circulatory Physiology 300 (6 …, 2011 | 90 | 2011 |
Obesity and insulin resistance promote atherosclerosis through an IFNγ-regulated macrophage protein network CA Reardon, A Lingaraju, KQ Schoenfelt, G Zhou, C Cui, H Jacobs-El, ... Cell reports 23 (10), 3021-3030, 2018 | 85 | 2018 |
The role of thin filament cooperativity in cardiac length-dependent calcium activation GP Farman, EJ Allen, KQ Schoenfelt, PH Backx, PP De Tombe Biophysical Journal 99 (9), 2978-2986, 2010 | 65 | 2010 |
Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling H Singhal, ME Greene, AL Zarnke, M Laine, R Al Abosy, YF Chang, ... Oncotarget 9 (4), 4282, 2018 | 61 | 2018 |
A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours C Cui, K Chakraborty, XA Tang, KQ Schoenfelt, A Hoffman, A Blank, ... Nature nanotechnology 16 (12), 1394-1402, 2021 | 57 | 2021 |
Ivacaftor-induced proteomic changes suggest monocyte defects may contribute to the pathogenesis of cystic fibrosis KB Hisert, KQ Schoenfelt, G Cooke, B Grogan, JL Launspach, ... American journal of respiratory cell and molecular biology 54 (4), 594-597, 2016 | 43 | 2016 |
Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia LE Risner, A Kuntimaddi, AA Lokken, NJ Achille, NW Birch, K Schoenfelt, ... Journal of Biological Chemistry 288 (41), 29901-29910, 2013 | 39 | 2013 |
Contextualised urinary biomarker analysis facilitates diagnosis of paediatric obstructive sleep apnoea L Becker, L Kheirandish-Gozal, E Peris, KQ Schoenfelt, D Gozal Sleep medicine 15 (5), 541-549, 2014 | 33 | 2014 |
CFTR modulator therapy enhances peripheral blood monocyte contributions to immune responses in people with cystic fibrosis KB Hisert, TP Birkland, KQ Schoenfelt, ME Long, B Grogan, S Carter, ... Frontiers in pharmacology 11, 1219, 2020 | 29 | 2020 |
Isolation of polymorphonuclear neutrophils and monocytes from a single sample of human peripheral blood C Cui, KQ Schoenfelt, KM Becker, L Becker STAR protocols 2 (4), 100845, 2021 | 24 | 2021 |
Ivacaftor decreases monocyte sensitivity to interferon-γ in people with cystic fibrosis KB Hisert, TP Birkland, KQ Schoenfelt, ME Long, B Grogan, S Carter, ... ERJ open research 6 (2), 2020 | 20 | 2020 |
An iron refractory phenotype in obese adipose tissue macrophages leads to adipocyte iron overload MK Ameka, WN Beavers, CM Shaver, LB Ware, VE Kerchberger, ... International journal of molecular sciences 23 (13), 7417, 2022 | 9 | 2022 |
SMRT regulates metabolic homeostasis and adipose tissue macrophage phenotypes in tandem JH Kahn, A Goddi, A Sharma, J Heiman, A Carmona, Y Li, A Hoffman, ... Endocrinology 161 (10), bqaa132, 2020 | 3 | 2020 |
Metabolically activated macrophages in mammary adipose tissue link obesity to triple-negative breast cancer P Tiwari, A Blank, C Cui, KQ Schoenfelt, G Zhou, Y Xu, AM Shah, ... bioRxiv, 370627, 2018 | 3 | 2018 |