Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway YH Zeidan, RW Jenkins, YA Hannun The Journal of cell biology 181 (2), 335-350, 2008 | 198 | 2008 |
Activation of acid sphingomyelinase by protein kinase Cδ-mediated phosphorylation YH Zeidan, YA Hannun Journal of Biological Chemistry 282 (15), 11549-11561, 2007 | 186 | 2007 |
Translational aspects of sphingolipid metabolism YH Zeidan, YA Hannun Trends in molecular medicine 13 (8), 327-336, 2007 | 172 | 2007 |
The acid sphingomyelinase/ceramide pathway: biomedical significance and mechanisms of regulation YH Zeidan, YA Hannun Current molecular medicine 10 (5), 454-466, 2010 | 166 | 2010 |
New insights on the use of desipramine as an inhibitor for acid ceramidase S Elojeimy, DH Holman, X Liu, A El-Zawahry, M Villani, JC Cheng, ... FEBS letters 580 (19), 4751-4756, 2006 | 137 | 2006 |
Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells J Jin, Q Hou, TD Mullen, YH Zeidan, J Bielawski, JM Kraveka, ... Journal of biological chemistry 283 (39), 26509-26517, 2008 | 108 | 2008 |
A novel role for protein kinase cδ‐mediated phosphorylation of acid sphingomyelinase in UV light‐induced mitochondrial injury YH Zeidan, BX Wu, RW Jenkins, LM Obeid, YA Hannun The FASEB Journal 22 (1), 183-193, 2008 | 103 | 2008 |
Isc1 regulates sphingolipid metabolism in yeast mitochondria H Kitagaki, LA Cowart, N Matmati, SV de Avalos, SA Novgorodov, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (11), 2849-2861, 2007 | 101 | 2007 |
Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells DH Holman, LS Turner, A El-Zawahry, S Elojeimy, X Liu, J Bielawski, ... Cancer chemotherapy and pharmacology 61, 231-242, 2008 | 98 | 2008 |
SMPDL3b modulates insulin receptor signaling in diabetic kidney disease A Mitrofanova, SK Mallela, GM Ducasa, TH Yoo, E Rosenfeld-Gur, ... Nature communications 10 (1), 2692, 2019 | 92 | 2019 |
Molecular targeting of acid ceramidase: implications to cancer therapy YH Zeidan, RW Jenkins, JB Korman, X Liu, LM Obeid, JS Norris, ... Current drug targets 9 (8), 653-661, 2008 | 88 | 2008 |
Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-α-induced PGE2 production YH Zeidan, BJ Pettus, S Elojeimy, T Taha, LM Obeid, T Kawamori, ... Journal of Biological Chemistry 281 (34), 24695-24703, 2006 | 82 | 2006 |
Defective Acid Sphingomyelinase Pathway with Pseudomonas aeruginosa Infection in Cystic Fibrosis H Yu, YH Zeidan, BX Wu, RW Jenkins, TR Flotte, YA Hannun, ... American journal of respiratory cell and molecular biology 41 (3), 367-375, 2009 | 65 | 2009 |
Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes A Ahmad, A Mitrofanova, J Bielawski, Y Yang, B Marples, A Fornoni, ... The FASEB Journal 31 (2), 771, 2017 | 61 | 2017 |
Postmastectomy radiation therapy in women with T1-T2 tumors and 1 to 3 positive lymph nodes: analysis of the breast international group 02-98 trial YH Zeidan, JG Habib, L Ameye, M Paesmans, E de Azambuja, RD Gelber, ... International Journal of Radiation Oncology* Biology* Physics 101 (2), 316-324, 2018 | 58 | 2018 |
Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma A Shamseddine, YH Zeidan, Z El Husseini, M Kreidieh, M Al Darazi, ... Radiation Oncology 15, 1-7, 2020 | 55 | 2020 |
Integrin-associated Lyn Kinase Promotes Cell Survival by Suppressing Acid Sphingomyelinase Activity∗ DA Chudakova, YH Zeidan, BW Wheeler, J Yu, SA Novgorodov, ... Journal of Biological Chemistry 283 (43), 28806-28816, 2008 | 54 | 2008 |
Involvement of sphingolipids in apoptin-induced cell killing X Liu, YH Zeidan, S Elojeimy, DH Holman, AM El-Zawahry, G Guo, ... Molecular Therapy 14 (5), 627-636, 2006 | 54 | 2006 |
Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation BX Wu, YH Zeidan, YA Hannun Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2009 | 50 | 2009 |
Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities P Azzam, M Mroueh, M Francis, A Abou Daher, YH Zeidan ecancermedicalscience 14, 2020 | 40 | 2020 |