PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer A Herzog, Y Bian, R Vander Broek, B Hall, J Coupar, H Cheng, ... Clinical Cancer Research 19 (14), 3808-3819, 2013 | 87 | 2013 |
Integrated genomic and functional microRNA analysis identifies miR-30-5p as a tumor suppressor and potential therapeutic nanomedicine in head and neck cancer AD Saleh, H Cheng, SE Martin, H Si, P Ormanoglu, S Carlson, PE Clavijo, ... Clinical Cancer Research 25 (9), 2860-2873, 2019 | 79 | 2019 |
Genomic and transcriptomic characterization links cell lines with aggressive head and neck cancers H Cheng, X Yang, H Si, AD Saleh, W Xiao, J Coupar, SM Gollin, RL Ferris, ... Cell reports 25 (5), 1332-1345. e5, 2018 | 78 | 2018 |
MEK inhibitor PD-0325901 overcomes resistance to PI3K/mTOR inhibitor PF-5212384 and potentiates antitumor effects in human head and neck squamous cell carcinoma S Mohan, R Vander Broek, S Shah, DF Eytan, ML Pierce, SG Carlson, ... Clinical Cancer Research 21 (17), 3946-3956, 2015 | 75 | 2015 |
SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2 DF Eytan, GE Snow, S Carlson, A Derakhshan, A Saleh, S Schiltz, ... Cancer Research 76 (18), 5442-5454, 2016 | 69 | 2016 |
Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma M Anne Conti, AD Saleh, LR Brinster, H Cheng, Z Chen, S Cornelius, ... Scientific reports 5 (1), 14068, 2015 | 62 | 2015 |
MEK inhibitor PD-0325901 overcomes resistance to CK2 inhibitor CX-4945 and exhibits anti-tumor activity in head and neck cancer Y Bian, J Han, V Kannabiran, S Mohan, H Cheng, J Friedman, L Zhang, ... International journal of biological sciences 11 (4), 411, 2015 | 51 | 2015 |
Attenuated TRAF3 fosters activation of alternative NF-κB and reduced expression of antiviral interferon, TP53, and RB to promote HPV-positive head and neck cancers J Zhang, T Chen, X Yang, H Cheng, SS Späth, PE Clavijo, J Chen, ... Cancer research 78 (16), 4613-4626, 2018 | 38 | 2018 |
Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV− and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy R Xiao, Y An, W Ye, A Derakhshan, H Cheng, X Yang, C Allen, Z Chen, ... Clinical Cancer Research 25 (21), 6463-6474, 2019 | 33 | 2019 |
Head and neck cancers promote an inflammatory transcriptome through coactivation of classic and alternative NF-κB pathways X Yang, H Cheng, J Chen, R Wang, A Saleh, H Si, S Lee, ... Cancer immunology research 7 (11), 1760-1774, 2019 | 25 | 2019 |
Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC) EL Morgan, T Toni, R Viswanathan, Y Robbins, X Yang, H Cheng, S Gunti, ... Cell Death & Differentiation 30 (5), 1382-1396, 2023 | 12 | 2023 |
Inhibiting WEE1 and IKK-RELA crosstalk overcomes TNFα resistance in head and neck cancers Z Hu, R Viswanathan, H Cheng, J Chen, X Yang, A Huynh, P Clavijo, ... Molecular Cancer Research 20 (6), 867-882, 2022 | 8 | 2022 |
Synaptic plasticity of inhibitory synapses onto medial olivocochlear efferent neurons L Torres Cadenas, H Cheng, CJC Weisz The Journal of physiology 600 (11), 2747-2763, 2022 | 7 | 2022 |
592P Bipolar androgen therapy (BAT) plus olaparib in men with metastatic castration-resistant prostate cancer (mCRPC) M Schweizer, R Gulati, T Yezefski, H Cheng, C Sievers, R Dumpit, ... Annals of Oncology 32, S639-S640, 2021 | 6 | 2021 |
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck N Nigam, B Bernard, S Sevilla, S Kim, MS Dar, D Tsai, Y Robbins, ... Cell reports 42 (7), 2023 | 5 | 2023 |
Combined inhibition of IAPs and WEE1 enhances TNFα-and radiation-induced cell death in head and neck squamous carcinoma T Toni, R Viswanathan, Y Robbins, S Gunti, X Yang, A Huynh, H Cheng, ... Cancers 15 (4), 1029, 2023 | 4 | 2023 |
Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas Y An, J Jeon, L Sun, A Derakhshan, J Chen, S Carlson, H Cheng, C Silvin, ... Scientific reports 11 (1), 6392, 2021 | 3 | 2021 |
Targeted therapy for head and neck squamous cell carcinoma using the novel SMAC-mimetic birinapant A Derakhshan, D Eytan, G Snow, S Carlson, A Saleh, H Cheng, S Schiltz, ... Cancer Research 76 (14_Supplement), 3821-3821, 2016 | 2 | 2016 |
Integrated functional RNAi screening and structural genomics identifies inverse co-modulators of TP53 family and NF-kB transitional activation as potential therapeutic targets … AD Saleh, S Cornelius, H Cheng, S Martin, P Ormanoglu, X Yang, Z Chen, ... Cancer Research 74 (19_Supplement), 3400-3400, 2014 | 2 | 2014 |
SUV420H1 as a novel target in HPV-negative head and neck squamous cell carcinoma A Moshiri, H Cheng, S Kim, V Saloura Cancer Research 83 (7_Supplement), 6284-6284, 2023 | 1 | 2023 |