| p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload M Sano, T Minamino, H Toko, H Miyauchi, M Orimo, Y Qin, H Akazawa, ... Nature 446 (7134), 444-448, 2007 | 1030 | 2007 |
| Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes K Matsuura, T Nagai, N Nishigaki, T Oyama, J Nishi, H Wada, M Sano, ... Journal of Biological Chemistry 279 (12), 11384-11391, 2004 | 865 | 2004 |
| Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II Y Zou, H Akazawa, Y Qin, M Sano, H Takano, T Minamino, N Makita, ... Nature cell biology 6 (6), 499-506, 2004 | 787 | 2004 |
| G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes M Harada, Y Qin, H Takano, T Minamino, Y Zou, H Toko, M Ohtsuka, ... Nature medicine 11 (3), 305-311, 2005 | 748 | 2005 |
| Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis AT Naito, I Shiojima, H Akazawa, K Hidaka, T Morisaki, A Kikuchi, ... Proceedings of the National Academy of Sciences 103 (52), 19812-19817, 2006 | 632 | 2006 |
| Roles of cardiac transcription factors in cardiac hypertrophy H Akazawa, I Komuro Circulation research 92 (10), 1079-1088, 2003 | 539 | 2003 |
| Angiogenesis and cardiac hypertrophy: maintenance of cardiac function and causative roles in heart failure T Oka, H Akazawa, AT Naito, I Komuro Circulation research 114 (3), 565-571, 2014 | 461 | 2014 |
| Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo T Oyama, T Nagai, H Wada, AT Naito, K Matsuura, K Iwanaga, ... The Journal of cell biology 176 (3), 329-341, 2007 | 413 | 2007 |
| Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes AT Naito, T Sumida, S Nomura, ML Liu, T Higo, A Nakagawa, K Okada, ... Cell 149 (6), 1298-1313, 2012 | 330 | 2012 |
| Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases H Akazawa, I Komuro Pharmacology & therapeutics 107 (2), 252-268, 2005 | 325 | 2005 |
| Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization M Ohtsuka, H Takano, Y Zou, H Toko, H Akazawa, Y Qin, M Suzuki, ... The FASEB journal 18 (7), 851-853, 2004 | 281 | 2004 |
| Integrins play a critical role in mechanical stress–induced p38 MAPK activation R Aikawa, T Nagai, S Kudoh, Y Zou, M Tanaka, M Tamura, H Akazawa, ... Hypertension 39 (2), 233-238, 2002 | 272 | 2002 |
| Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases H Takano, Y Zou, H Hasegawa, H Akazawa, T Nagai, I Komuro Antioxidants and Redox Signaling 5 (6), 789-794, 2003 | 258 | 2003 |
| Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents I Shimizu, T Minamino, H Toko, S Okada, H Ikeda, N Yasuda, K Tateno, ... The Journal of clinical investigation 120 (5), 1506-1514, 2010 | 253 | 2010 |
| Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure T Kamo, H Akazawa, W Suda, A Saga-Kamo, Y Shimizu, H Yagi, Q Liu, ... PloS one 12 (3), e0174099, 2017 | 252 | 2017 |
| Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization K Tateno, T Minamino, H Toko, H Akazawa, N Shimizu, S Takeda, ... Circulation research 98 (9), 1194-1202, 2006 | 248 | 2006 |
| Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease S Koyama, K Ito, C Terao, M Akiyama, M Horikoshi, Y Momozawa, ... Nature genetics 52 (11), 1169-1177, 2020 | 244 | 2020 |
| Cardiac mast cells cause atrial fibrillation through PDGF-A–mediated fibrosis in pressure-overloaded mouse hearts C Liao, H Akazawa, M Tamagawa, K Ito, N Yasuda, Y Kudo, R Yamamoto, ... The Journal of clinical investigation 120 (1), 242-253, 2010 | 235 | 2010 |
| Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure S Nomura, M Satoh, T Fujita, T Higo, T Sumida, T Ko, T Yamaguchi, ... Nature communications 9 (1), 4435, 2018 | 223 | 2018 |
| Conformational switch of angiotensin II type 1 receptor underlying mechanical stress‐induced activation N Yasuda, S Miura, H Akazawa, T Tanaka, Y Qin, Y Kiya, S Imaizumi, ... EMBO reports 9 (2), 179-186, 2008 | 216 | 2008 |
