TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis A Bafica, CA Scanga, CG Feng, C Leifer, A Cheever, A Sher The Journal of experimental medicine 202 (12), 1715-1724, 2005 | 854 | 2005 |
Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology VP Mohan, CA Scanga, K Yu, HM Scott, KE Tanaka, E Tsang, MC Tsai, ... Infection and immunity 69 (3), 1847-1855, 2001 | 751 | 2001 |
Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells CA Scanga, J Aliberti, D Jankovic, F Tilloy, S Bennouna, EY Denkers, ... The Journal of Immunology 168 (12), 5997-6001, 2002 | 623 | 2002 |
Prevention of tuberculosis in macaques after intravenous BCG immunization PA Darrah, JJ Zeppa, P Maiello, JA Hackney, MH Wadsworth, TK Hughes, ... Nature 577 (7788), 95-102, 2020 | 557 | 2020 |
Depletion of Cd4+ T Cells Causes Reactivation of Murine Persistent Tuberculosis despite Continued Expression of Interferon γ and Nitric Oxide Synthase 2 CA Scanga, VP Mohan, K Yu, H Joseph, K Tanaka, J Chan, JAL Flynn The Journal of experimental medicine 192 (3), 347-358, 2000 | 510 | 2000 |
Reactivation of latent tuberculosis: variations on the Cornell murine model CA Scanga, VP Mohan, H Joseph, K Yu, J Chan, JAL Flynn Infection and immunity 67 (9), 4531-4538, 1999 | 331 | 1999 |
Effects of aminoguanidine on latent murine tuberculosis JAL Flynn, CA Scanga, KE Tanaka, J Chan The Journal of Immunology 160 (4), 1796-1803, 1998 | 318 | 1998 |
Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase–dependent lipoxin production A Bafica, CA Scanga, C Serhan, F Machado, S White, A Sher, J Aliberti The Journal of clinical investigation 115 (6), 1601-1606, 2005 | 313 | 2005 |
Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like … CG Feng, CA Scanga, CM Collazo-Custodio, AW Cheever, S Hieny, ... The Journal of immunology 171 (9), 4758-4764, 2003 | 269 | 2003 |
MyD88-Deficient Mice Display a Profound Loss in Resistance to Mycobacterium tuberculosis Associated with Partially Impaired Th1 Cytokine and Nitric Oxide … CA Scanga, A Bafica, CG Feng, AW Cheever, S Hieny, A Sher Infection and immunity 72 (4), 2400-2404, 2004 | 268 | 2004 |
CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages NV Serbina, CC Liu, CA Scanga, JAL Flynn The Journal of Immunology 165 (1), 353-363, 2000 | 252 | 2000 |
The inducible nitric oxide synthase locus confers protection against aerogenic challenge of both clinical and laboratory strains of Mycobacterium tuberculosis in mice CA Scanga, VP Mohan, K Tanaka, D Alland, JAL Flynn, J Chan Infection and immunity 69 (12), 7711-7717, 2001 | 232 | 2001 |
Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge … R Sun, YAW Skeiky, A Izzo, V Dheenadhayalan, Z Imam, E Penn, ... Vaccine 27 (33), 4412-4423, 2009 | 209 | 2009 |
Radiologic responses in cynomolgus macaques for assessing tuberculosis chemotherapy regimens PL Lin, T Coleman, JPJ Carney, BJ Lopresti, J Tomko, D Fillmore, ... Antimicrobial agents and chemotherapy 57 (9), 4237-4244, 2013 | 194 | 2013 |
Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production CG Feng, D Jankovic, M Kullberg, A Cheever, CA Scanga, S Hieny, ... The Journal of Immunology 174 (7), 4185-4192, 2005 | 191 | 2005 |
Modeling tuberculosis in nonhuman primates CA Scanga, JAL Flynn Cold Spring Harbor perspectives in medicine 4 (12), a018564, 2014 | 162 | 2014 |
CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection V Lazarevic, AJ Myers, CA Scanga, JAL Flynn Immunity 19 (6), 823-835, 2003 | 160 | 2003 |
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ... Immunity 55 (5), 827-846. e10, 2022 | 150 | 2022 |
PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis MT Coleman, RY Chen, M Lee, PL Lin, LE Dodd, P Maiello, LE Via, Y Kim, ... Science translational medicine 6 (265), 265ra167-265ra167, 2014 | 147 | 2014 |
SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and … AL Hartman, S Nambulli, CM McMillen, AG White, NL Tilston-Lunel, ... PLoS pathogens 16 (9), e1008903, 2020 | 144 | 2020 |