Reducing astrocyte calcium signaling in vivo alters striatal microcircuits and causes repetitive behavior X Yu, AMW Taylor, J Nagai, P Golshani, CJ Evans, G Coppola, BS Khakh Neuron 99 (6), 1170-1187. e9, 2018 | 288 | 2018 |
Hyperactivity with disrupted attention by activation of an astrocyte synaptogenic cue J Nagai, AK Rajbhandari, MR Gangwani, A Hachisuka, G Coppola, ... Cell 177 (5), 1280-1292. e20, 2019 | 276 | 2019 |
A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP MA Lobas, R Tao, J Nagai, MT Kronschläger, PM Borden, JS Marvin, ... Nature communications 10 (1), 711, 2019 | 235 | 2019 |
Improved tools to study astrocytes X Yu*, J Nagai*, BS Khakh Nature Reviews Neuroscience 21 (3), 121-138, 2020 | 223 | 2020 |
Behaviorally consequential astrocytic regulation of neural circuits J Nagai*, X Yu*, T Papouin, E Cheong, MR Freeman, KR Monk, ... Neuron 109 (14), 2256-2274.e9, 2021 | 178 | 2021 |
Context-specific striatal astrocyte molecular responses are phenotypically exploitable X Yu*, J Nagai*, M Marti-Solano, JS Soto, G Coppola, MM Babu, ... Neuron 108 (6), 1146-1162. e10, 2020 | 83 | 2020 |
CRMP4 suppresses apical dendrite bifurcation of CA1 pyramidal neurons in the mouse hippocampus E Niisato, J Nagai, N Yamashita, T Abe, H Kiyonari, Y Goshima, ... Developmental neurobiology 72 (11), 1447-1457, 2012 | 66 | 2012 |
Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats W Wang, PJ Schuette, J Nagai, BC Tobias, FMCV Reis, S Ji, ... Neuron 109 (11), 1848-1860. e8, 2021 | 60 | 2021 |
Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK J Nagai, A Bellafard, Z Qu, X Yu, M Ollivier, MR Gangwani, B Diaz-Castro, ... Neuron 109 (14), 2256-2274. e9, 2021 | 55 | 2021 |
Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses J Nagai, K Owada, Y Kitamura, Y Goshima, T Ohshima Experimental neurology 277, 283-295, 2016 | 53 | 2016 |
Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation J Nagai, Y Kitamura, K Owada, N Yamashita, K Takei, Y Goshima, ... Scientific reports 5 (1), 8269, 2015 | 45 | 2015 |
Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons E Niisato, J Nagai, N Yamashita, F Nakamura, Y Goshima, T Ohshima Developmental neurobiology 73 (2), 142-151, 2013 | 45 | 2013 |
Phosphorylation of CRMP2 by Cdk5 regulates dendritic spine development of cortical neuron in the mouse hippocampus X Jin, K Sasamoto, J Nagai, Y Yamazaki, K Saito, Y Goshima, T Inoue, ... Neural Plasticity 2016, 2016 | 37 | 2016 |
CRMPs function in neurons and glial cells: potential therapeutic targets for neurodegenerative diseases and CNS injury J Nagai, R Baba, T Ohshima Molecular Neurobiology 54, 4243-4256, 2017 | 33 | 2017 |
CRMP4 mediates MAG-induced inhibition of axonal outgrowth and protection against Vincristine-induced axonal degeneration J Nagai, Y Goshima, T Ohshima Neuroscience Letters 519 (1), 56-61, 2012 | 27 | 2012 |
Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury S Kondo, K Takahashi, Y Kinoshita, J Nagai, S Wakatsuki, T Araki, ... Scientific reports 9 (1), 7188, 2019 | 21 | 2019 |
Lanthionine ketimine ester promotes locomotor recovery after spinal cord injury by reducing neuroinflammation and promoting axon growth K Kotaka, J Nagai, K Hensley, T Ohshima Biochemical and biophysical research communications 483 (1), 759-764, 2017 | 21 | 2017 |
CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain R Takaya, J Nagai, W Piao, E Niisato, T Nakabayashi, Y Yamazaki, ... Brain Research 1655, 161-167, 2017 | 18 | 2017 |
Deletion of Crmp4 attenuates CSPG-induced inhibition of axonal growth and induces nociceptive recovery after spinal cord injury J Nagai, R Takaya, W Piao, Y Goshima, T Ohshima Molecular and Cellular Neuroscience 74, 42-48, 2016 | 16 | 2016 |
Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine‐induced Parkinson’s model mice K Togashi, M Hasegawa, J Nagai, A Tonouchi, D Masukawa, K Hensley, ... Genes to Cells 24 (1), 31-40, 2019 | 10 | 2019 |