Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates P García-Huerta, P Troncoso-Escudero, D Wu, A Thiruvalluvan, ... Acta neuropathologica 140, 737-764, 2020 | 53 | 2020 |
AAV-mediated gene therapy halts retinal degeneration in PDE6β-deficient dogs V Pichard, N Provost, A Mendes-Madeira, L Libeau, P Hulin, KT Tshilenge, ... Molecular Therapy 24 (5), 867-876, 2016 | 45 | 2016 |
Vitrectomy before intravitreal injection of AAV2/2 vector promotes efficient transduction of retinal ganglion cells in dogs and nonhuman primates KT Tshilenge, B Ameline, M Weber, A Mendes-Madeira, S Nedellec, ... Human gene therapy methods 27 (3), 122-134, 2016 | 38 | 2016 |
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels BJ Bailus, SM Scheeler, J Simons, MA Sanchez, KT Tshilenge, ... Autophagy 17 (12), 4119-4140, 2021 | 34 | 2021 |
Restriction of replication of oncolytic herpes simplex virus with a deletion of γ34. 5 in glioblastoma stem-like cells C Peters, M Paget, KT Tshilenge, D Saha, S Antoszczyk, A Baars, T Frost, ... Journal of Virology 92 (15), 10.1128/jvi. 00246-18, 2018 | 32* | 2018 |
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase J Voisin, F Farina, S Naphade, M Fontaine, KT Tshilenge, ... Aging Cell 19 (11), e13226, 2020 | 20 | 2020 |
Modeling polyglutamine expansion diseases with induced pluripotent stem cells S Naphade, KT Tshilenge, LM Ellerby Neurotherapeutics 16 (4), 979-998, 2019 | 20 | 2019 |
Nuclear receptor Nr4a1 regulates striatal striosome development and dopamine D1 receptor signaling MD Cirnaru, C Melis, T Fanutza, S Naphade, KT Tshilenge, BS Muntean, ... eneuro 6 (5), 2019 | 17 | 2019 |
Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina B Ameline, KT Tshilenge, M Weber, M Biget, L Libeau, R Caplette, ... Gene therapy 24 (11), 735-741, 2017 | 15 | 2017 |
Proteomic analysis of Huntington’s disease medium spiny neurons identifies alterations in lipid droplets KT Tshilenge, CG Aguirre, J Bons, AA Gerencser, N Basisty, S Song, ... Molecular & Cellular Proteomics 22 (5), 2023 | 11 | 2023 |
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation MD Cirnaru, S Song, KT Tshilenge, C Corwin, J Mleczko, CG Aguirre, ... Elife 10, e65979, 2021 | 11 | 2021 |
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease S Song, J Creus Muncunill, C Galicia Aguirre, KT Tshilenge, BW Hamilton, ... Biomedicines 10 (10), 2377, 2022 | 3 | 2022 |
PNA microprobe for label-free detection of expanded trinucleotide repeats N Asefifeyzabadi, G Durocher, KT Tshilenge, T Alam, LM Ellerby, ... RSC advances 12 (13), 7757-7761, 2022 | 3 | 2022 |
Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing KT Tshilenge, J Bons, CG Aguirre, C Geronimo-Olvera, S Shah, J Rose, ... Neurobiology of Disease 190, 106367, 2024 | 1 | 2024 |
Transcriptomic Characterization Reveals Disrupted Medium Spiny Neuron Trajectories in Huntington's Disease and Possible Therapeutic Avenues K Tshilenge, E Battistoni, A Lopez-Ramirez, S Naphade, K Perez, S Song, ... | | 2023 |
Transcriptomic characterization reveals disrupted medium spiny neuron trajectories in Huntington’s disease and possible therapeutic avenues CG Aguirre, KT Tshilenge, E Battistoni, A Lopez-Ramirez, S Naphade, ... bioRxiv, 2023.04. 30.538872, 2023 | | 2023 |
PNA Microprobe for Label-Free Detection of Nucleic Acid Repeat Mutations M Shamsi, N Asefifeyzabadi, G Durocher, KT Tshilenge, L Ellerby | | 2021 |
Optimisation du transfert de gène dans les cellules ganglionnaires rétiniennes de chien et de primate non-humain avec un vecteur AAV2: implications pour le traitement par une … K tshitoko Tshilenge Nantes, 2016 | | 2016 |
Vitreous body: A barrier for AAV-mediated gene transfer to inner retinal neurons of macaque TK Tshilenge, B Ameline, M Weber, G Le Meur, JY Deschamps, ... Investigative Ophthalmology & Visual Science 57 (12), 100-100, 2016 | | 2016 |
Evaluation of AAV-based optogene transfer for the treatment of canine models of inherited retinal dystrophies B Ameline, KT Tshilenge, L Libeau, A Mendes-Madeira, N Provost, ... Investigative Ophthalmology & Visual Science 57 (12), 118-118, 2016 | | 2016 |