Novel mechanisms of G-protein-coupled receptors functions: AT1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk AD Tóth, G Turu, L Hunyady, A Balla Best Practice & Research Clinical Endocrinology & Metabolism 32 (2), 69-82, 2018 | 58 | 2018 |
Heterologous phosphorylation–induced formation of a stability lock permits regulation of inactive receptors by β-arrestins AD Tóth, S Prokop, P Gyombolai, P Várnai, A Balla, VV Gurevich, ... Journal of Biological Chemistry 293 (3), 876-892, 2018 | 53 | 2018 |
Mutations in the ‘DRY’motif of the CB1 cannabinoid receptor result in biased receptor variants P Gyombolai, AD Tóth, D Tímár, G Turu, L Hunyady Journal of molecular endocrinology 54 (1), 75-89, 2015 | 43 | 2015 |
Investigation of the fate of type I angiotensin receptor after biased activation G Szakadáti, AD Tóth, I Oláh, LS Erdélyi, T Balla, P Várnai, L Hunyady, ... Molecular pharmacology 87 (6), 972-981, 2015 | 38 | 2015 |
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells S Prokop, P Ábrányi-Balogh, B Barti, M Vámosi, M Zöldi, L Barna, ... Nature communications 12 (1), 6505, 2021 | 30 | 2021 |
Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization AD Tóth, P Gyombolai, B Szalai, P Várnai, G Turu, L Hunyady Molecular and cellular endocrinology 442, 113-124, 2017 | 30 | 2017 |
Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes AD Tóth, R Schell, M Lévay, C Vettel, P Theis, C Haslinger, F Alban, ... EMBO molecular medicine 10 (7), e8536, 2018 | 21 | 2018 |
Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors S Prokop, NA Perry, SA Vishnivetskiy, AD Toth, A Inoue, G Milligan, ... Cellular signalling 36, 98-107, 2017 | 18 | 2017 |
Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor G Turu, E Soltész-Katona, AD Tóth, C Juhász, M Cserző, Á Misák, A Balla, ... Frontiers in Endocrinology 12, 714561, 2021 | 13 | 2021 |
A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase AD Tóth, D Garger, S Prokop, E Soltész-Katona, P Várnai, A Balla, G Turu, ... Journal of Biological Chemistry 296, 2021 | 12 | 2021 |
Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones L Szalai, A Sziráki, LS Erdélyi, KB Kovács, M Tóth, AD Tóth, G Turu, ... Frontiers in Pharmacology 13, 811836, 2022 | 10 | 2022 |
Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells JB Gém, KB Kovács, L Szalai, G Szakadáti, E Porkoláb, B Szalai, G Turu, ... Cells 10 (12), 3538, 2021 | 9 | 2021 |
Soluble B-cell maturation antigen as a monitoring marker for multiple myeloma Á Wiedemann, VR Szita, R Horváth, A Szederjesi, A Sebő, AD Tóth, ... Pathology and Oncology Research 29, 1611171, 2023 | 7 | 2023 |
Cardiac Amyloidosis with Normal Wall Thickness: Prevalence, Clinical Characteristics and Outcome in a Retrospective Analysis D Nagy, K Révész, G Peskó, G Varga, L Horváth, P Farkas, AD Tóth, ... Biomedicines 10 (7), 1765, 2022 | 7 | 2022 |
Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB1) Receptor VB Horváth, E Soltész-Katona, É Wisniewski, A Rajki, E Halász, B Enyedi, ... Frontiers in Endocrinology 12, 740913, 2021 | 3 | 2021 |
An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression KB Kovács, L Szalai, P Szabó, JB Gém, S Barsi, B Szalai, B Perey-Simon, ... International Journal of Molecular Sciences 24 (4), 3968, 2023 | 2 | 2023 |
Beneficial Effect of Lenalidomide-Dexamethason Treatment in Relapsed/Refractory Multiple Myeloma Patients: Results of Real-Life Data From 11 Hungarian Centers G Varga, A Dávid Tóth, V Réka Szita, Z Csukly, A Hardi, J Gaál-Weisinger, ... Pathology & Oncology Research 27, 613264, 2021 | 2 | 2021 |
G protein–coupled receptor endocytosis generates spatiotemporal bias in β-arrestin signaling AD Tóth, B Szalai, OT Kovács, D Garger, S Prokop, E Soltész-Katona, ... Science Signaling 17 (842), eadi0934, 2024 | 1 | 2024 |
ArreSTick motif controls β-arrestin-binding stability and extends phosphorylation-dependent β-arrestin interactions to non-receptor proteins AD Tóth, E Soltész-Katona, K Kis, V Guti, S Gilzer, S Prokop, R Boros, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
Receptor endocytosis orchestrates the spatiotemporal bias of β-arrestin signaling AD Toth, B Szalai, OT Kovacs, D Garger, S Prokop, A Balla, A Inoue, ... bioRxiv, 2023.04. 27.538587, 2023 | 1 | 2023 |